Cyclophilin 40 (PPID) (NM_005038) Human Untagged Clone
CAT#: SC116955
PPID (untagged)-Human peptidylprolyl isomerase D (PPID)
CNY 3,656.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CYP-40; CYPD |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC116955 sequence for NM_005038 edited (data generated by NextGen Sequencing)
ATGTCGCACCCGTCCCCCCAAGCCAAGCCCTCCAACCCCAGTAACCCTCGAGTCTTCTTT GACGTGGACATCGGAGGGGAGCGAGTTGGTCGAATTGTCTTAGAATTGTTTGCAGATATC GTACCCAAAACTGCGGAAAATTTTCGTGCACTGTGTACAGGAGAAAAAGGCATTGGACAC ACGACTGGGAAACCTCTCCATTTCAAAGGATGCCCTTTTCATCGAATTATTAAGAAATTT ATGATTCAGGGTGGAGACTTCTCAAATCAGAATGGGACAGGTGGAGAAAGTATTTATGGT GAAAAATTTGAAGATGAAAATTTCCATTACAAGCATGATCGGGAGGGTTTACTGAGCATG GCAAATGCAGGCCGCAACACAAACGGTTCTCAGTTTTTTATCACAACAGTTCCAACTCCT CATTTGGATGGGAAACATGTGGTGTTTGGCCAAGTAATTAAAGGAATAGGAGTGGCAAGG ATATTGGAAAATGTGGAAGTGAAAGGTGAAAAACCTGCTAAATTGTGCGTTATTGCAGAA TGTGGAGAATTGAAGGAAGGAGATGACGGGGGAATATTCCCAAAAGATGGCTCTGGCGAC AGTCATCCAGATTTCCCTGAGGATGCGGATATAGATTTAAAAGATGTAGATAAAATTTTA TTAATAACAGAAGACTTAAAAAACATTGGAAATACTTTTTTCAAATCCCAGAACTGGGAG ATGGCTATTAAAAAATATGCAGAAGTTTTAAGATACGTGGACAGTTCAAAGGCTGTTATT GAGACAGCAGATAGAGCCAAGCTGCAACCTATAGCTTTAAGCTGTGTACTGAATATTGGT GCTTGTAAACTGAAGATGTCAAATTGGCAGGGAGCAATTGACAGTTGTTTAGAGGCTCTT GAACTAGACCCATCAAATACCAAAGCATTGTACCGCAGAGCTCAAGGATGGCAAGGATTA AAAGAATATGATCAAGCATTGGCTGATCTTAAGAAAGCTCAGGGGATAGCACCAGAAGAT AAAGCTATCCAGGCAGAATTGCTGAAAGTCAAACAAAAGATAAAGGCACAGAAAGATAAA GAGAAGGCAGTATATGCAAAAATGTTTGCTTAG Clone variation with respect to NM_005038.2 >OriGene 5' read for NM_005038 unedited
NGTACGAATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGGAGACGG ACTCTGGAGTTTGGGCGGCCCGGGCGGCCACTAGGTACTCTGATATTCCGTACTAAACAC GTCTGCAAGTCAAGATGTCGCACCCGTCCCCCCAAGCCAAGCCCTCCAACCCCAGTAACC CTCGAGTCTTCTTTGACGTGGACATCGGAGGGGAGCGAGTTGGTCGAATTGTCTTAGAAT TGTTTGCAGATATCGTACCCAAAACTGCGGAAAATTTTCGTGCACTGTGTACAGGAGAAA AAGGCATTGGACACACGACTGGGAAACCTCTCCATTTCAAAGGATGCCCTTTTCATCGAA TTATTAAGAAATTTATGATTCAGGGTGGAGACTTCTCAAATCAGAATGGGACAGGTGGAG AAAGTATTTATGGTGAAAAATTTGAAGATGAAAATTTCCATTACAAGCATGATCGGGAGG GTTTACTGAGCATGGCAAATGCAGGCCGCAACACAAACGGTTCTCAGTTTTTTATCACAA CAGTTCCAACTCCTCATTTGGATGGGAAACATGTGGTGTTTGGCCAAGTAATTAAAGGAA TAGGAGTGGCAAGGATATTGGAAAATGTGGAAGTGAAAGGTGAAAAACCTGCTAAATTGT GCGTTATTGCAGAATGTGGAGAATTGAAGGAAGGAGATGACGGNGGAATATTCCCAAAAG ATGGCTCTGGCGACAGTCATCCAGATTTCCCTGAGGATGCNGATATAGATNTAAAAGATG TAGATAAAATTTTATTAATAACAGAAGACTTANAAACATTGGAAATACTTTNTTCAATNC CAGAACTGGAGATGGCTATTAAAAAATGCAGAGNTTAAAGATCGTGGACAGTCAAAGCTG TTATGAGACGCANAAGAGCAGCTGCACTATACTTAAGCTGGTCTGAAATTGGGGCTTGA >OriGene 3' read for NM_005038 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAGCTCTCATCTCTTTATTCAATA AGATGTGTCTTTACAAGTTTAAAAAGACTGGACACCATTATTTTTTATGAATAATGCACA TAACCATTTTAAAAAACATTTTACTTGGCCGGGCACGGTGGCTCACACCTGTAATCCCAG CACTTTGGGAGGCCAAGGCGGGGTGGATCACAAGGTCAGGAGTTCAAGACCAACGTGACG TGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGG CACGTGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGCAGGAGAATTGCTTGAACCCGGG AGGCAGAGGATGCAGTGAGCCGAGATTGCGCCACCGCACTCCAGCCTGGGTGACAGAGCA AGACTCCATCTCAAAGAAACAAACAAAACCACTTTACTTACTGTATTGTGACATGTGTAT TAAGCATGAACCCCTATCAGTACTCCTAAACTGTAAACAGTAAGGAACTAAGGTGTCAAA AGAAACACATTAGGGATCATATTCATAGACAAAAACCTTTACATTTTCTTATTGCATTTA TACAATCAACACACAATAAGCAAACCTGAATCCTTTCTCAGCAAACATTTTTGCCTATAC TGCCCTCCCTTTATCTTTCCGCGCCTTTATCTTTTGTTTGACTTTCACCAATTCCGCCTC GATAGCTCTATCCTCCTGGGGCACCCNCCTGAGCTTTCTTAAGAACACCCCACGCTCGAC CACTTTTCTTTTATCCCTTGCATCCCTTGACCCGCGCGGCCACCGCTCCGGCCTCCGACG GGGCTCATCCAATAGCCTTTAAACTACGGTAACTGTTACCGGCCAATTGAAAGTTTGGCG GACAGGCCCAACTCCCGGCCCACCTCAACCATCGTGTTGCCCTGCCCATATGGCGGCCCA CAAACGCTCCCCCGGTCCTCTTCGCAATCCCCCGTTCCTT |
Restriction Sites | NotI-NotI |
ACCN | NM_005038 |
Insert Size | 1880 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_005038.2, NP_005029.1 |
RefSeq Size | 1851 bp |
RefSeq ORF | 1113 bp |
Locus ID | 5481 |
UniProt ID | Q08752 |
Domains | TPR, pro_isomerase |
Protein Families | Stem cell - Pluripotency |
Protein Pathways | Calcium signaling pathway, Huntington's disease, Parkinson's disease |
Gene Summary | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma
,L Wei, Y Zhou, Q Dai, C Qiao, L Zhao, + et al.,
Cell Death and Disease 4, e601 doi:10.1038/cddis.2013.131
,PubMed ID 23598413
[PPID]
|
Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore
,Tiffany T. Nguyen, Mark V. Stevens, Mark Kohr, Charles Steenbergen, Michael N. Sack, and Elizabeth Murphy,
J. Biol. Chem., Oct 2012; 287: 34496 - 34498.
[PPID]
|
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Other Versions
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RC206039 | PPID (Myc-DDK-tagged)-Human peptidylprolyl isomerase D (PPID) |
CNY 3,656.00 |
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RC206039L3 | Lenti ORF clone of Human peptidylprolyl isomerase D (PPID), Myc-DDK-tagged |
CNY 5,890.00 |
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RC206039L4 | Lenti ORF clone of Human peptidylprolyl isomerase D (PPID), mGFP tagged |
CNY 5,890.00 |
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RG206039 | PPID (tGFP-tagged) - Human peptidylprolyl isomerase D (PPID) |
CNY 5,256.00 |
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