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PCSK7 (NM_004716) Human Untagged Clone
CAT＃: SC117224
PCSK7 (untagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7)
CNY 5,760.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LPC; PC7; PC8; SPC7 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117224 sequence for NM_004716 edited (data generated by NextGen Sequencing)
ATGCCGAAGGGGAGGCAGAAAGTGCCACACTTGGATGCCCCCCTGGGCCTGCCCACCTGC CTCTGGCTGGAATTAGCCGGGCTCTTCTTACTGGTTCCCTGGGTCATGGGCCTGGCAGGG ACAGGTGGGCCTGATGGCCAGGGCACAGGGGGGCCGAGCTGGGCTGTGCACCTGGAAAGC CTGGAAGGTGACGGGGAGGAAGAGACTCTGGAGCAGCAGGCGGATGCCTTGGCCCAGGCA GCAGGGCTGGTGAATGCTGGACGCATCGGAGAGCTTCAGGGGCACTACCTCTTTGTCCAG CCTGCTGGGCACAGGCCGGCCCTGGAGGTGGAGGCCATCCGGCAGCAGGTGGAGGCTGTG TTGGCTGGGCATGAAGCTGTGCGCTGGCACTCAGAGCAGAGGCTGCTAAGGCGGGCCAAG CGCAGCGTCCACTTCAACGACCCCAAGTACCCGCAGCAATGGCACCTGAATAACCGACGG AGCCCGGGCAGGGACATCAACGTGACGGGTGTGTGGGAACGCAATGTGACTGGGCGAGGG GTGACGGTGGTGGTAGTGGATGACGGAGTGGAACACACCATCCAGGACATTGCACCCAAC TATAGCCCTGAGGGTAGCTATGACCTCAACTCTAATGACCCTGACCCCATGCCCCACCCG GATGTGGAGAATGGCAACCACCATGGCACGCGATGTGCAGGAGAGATCGCGGCTGTGCCC AACAACAGCTTCTGTGCCGTGGGCGTGGCCTACGGGAGCCGCATCGCAGGTATCCGGGTA CTGGATGGACCTCTCACAGACAGCATGGAGGCAGTGGCGTTCAACAAGCACTATCAGATC AATGACATCTACAGCTGCAGCTGGGGACCAGATGACGATGGGAAGACAGTGGATGGCCCC CATCAGCTTGGAAAGGCTGCCTTACAACATGGGGTGATTGCTGGTCGCCAGGGCTTTGGG AGCATCTTTGTGGTAGCCAGTGGCAACGGAGGCCAACACAACGACAACTGCAACTACGAT GGCTACGCCAACTCCATCTACACCGTCACCATAGGAGCTGTGGATGAGGAGGGACGCATG CCTTTCTATGCAGAAGAATGTGCCTCCATGCTGGCAGTCACCTTCAGTGGTGGGGACAAG ATGCTTCGGAGCATTGTGACCACTGACTGGGACCTTCAGAAGGGCACTGGCTGCACTGAG GGCCACACAGGGACCTCAGCTGCAGCGCCTCTGGCAGCTGGCATGATAGCCTTAATGCTG CAGGTGCGGCCCTGCCTCACGTGGCGTGACGTCCAGCACATCATTGTCTTCACAGCCACC CGGTATGAGGATCGCCGTGCAGAGTGGGTCACCAACGAGGCAGGCTTCAGCCATAGCCAC CAGCACGGTTTCGGCCTCCTCAACGCCTGGAGGCTCGTGAATGCAGCCAAGATCTGGACA TCTGTCCCTTACTTAGCATCCTACGTCAGTCCCGTGTTAAAAGAAAACAAGGCGATTCCG CAGTCCCCCCGTTCCCTGGAGGTCCTGTGGAATGTCAGCAGGATGGACCTGGAGATGTCA GGGCTGAAGACCCTGGAGCATGTGGCAGTGACAGTCTCCATCACTCACCCACGGCGCGGC AGCTTGGAGCTGAAGCTGTTCTGCCCCAGTGGCATGATGTCCCTCATCGGCGCCCCCCGC AGCATGGACTCGGATCCCAACGGCTTCAATGACTGGACCTTCTCCACTGTGCGATGCTGG GGGGAGAGAGCCCGAGGGACCTACAGGCTGGTCATCAGGGATGTCGGGGATGAGTCATTC CAGGTCGGCATCCTCCGGCAATGGCAGCTGACCCTATATGGCTCTGTGTGGAGTGCAGTA GACATCAGGGACAGACAAAGGCTGTTAGAGAGTGCCATGAGTGGAAAATACCTGCACGAT GACTTCGCCCTGCCCTGCCCACCGGGGCTGAAAATTCCTGAGGAAGATGGTTACACCATC ACCCCCAACACCCTCAAGACCCTGGTGCTGGTAGGCTGTTTCACCGTCTTCTGGACCGTT TACTACATGCTGGAAGTATATTTGAGCCAGAGGAATGTGGCTTCCAATCAAGTTTGTAGG AGTGGACCCTGCCACTGGCCCCATCGGAGCCGGAAAGCCAAGGAGGAAGGGACAGAGCTA GAATCAGTGCCACTTTGCAGCAGCAAGGATCCAGACGAAGTGGAAACAGAGAGCAGGGGC CCTCCCACCACCTCTGACCTCCTTGCCCCAGACCTGCTGGAGCAAGGGGACTGGAGCCTG TCCCAGAACAAGAGCGCCCTGGACTGCCCTCATCAGCACCTAGACGTACCGCACGGGAAG GAGGAGCAGATCTGCTGA Clone variation with respect to NM_004716.2 1770 t=>g;2037 t=>c >OriGene 5' read for NM_004716 unedited
TCCCCGCCCTGTTGNCGCAAAGGGCGGTATGCGTGTACGGTGGGAGGTCTATATAAGCAG AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA TTCGGCACGAGGGCGGCGGCAGCTGCGGCGGGGCCGGTCTGTAGCCTTTGCTGAGTCAAC ACTACTCACAGTGAAAGTGATGCCTTTTCTCCATTTGCACAACATGAGTGTGACGTGGTT AGCCAGACCAGGAGCTCAACCTCATGTAGAATCCAGTCCACTGCTCTGATGCCGAAGGGG AGGCAGAAAGTGCCACACTTGGATGCCCCCCTGGGCCTGCCCACCTGCCTCTGGCTGGAA TTAGCCGGGCTCTTCTTACTGGTTCCCTGGGTCATGGGCCTGGCAGGGACAGGTGGGCCT GATGGCCAGGGCACAGGGGGGCCGAGCTGGGCTGTGCACCTGGAAAGCCTGGAAGGTGAC GGGGAGGAAGAGACTCTGGAGCAGCAGGCGGATGCCTTGGCCCAGGCAGCAGGGCTGGTG AATGCTGGACGCATCGGAGAGCTTCAGGGGCACTACCTCTTTGTCCAGCCTGCTGGGCAC AGGCCGGCCCTGGAGGTGGAGGCCATCCGGCAGCAGGTGGAGGCTGTGTTGGCTGGGCAT GAAGCTGTGCGCTGGCACTCAGAGCAGANGCTGCTAAGGCGGGCCAAGCGCAGCGTTCAC TTCAACGACCCCAAGTACCCGCAGCAATGGCACCTGAATAACCGACGGAGCCCGGGCAGG GACATCAACGTGACGGGTGTGTGGGAAACGCATGTGACTGGGCGAAGGGTGACCGTGGTG GTATTGGATGACCGAGTGGAACACACATCCAGGACATGCACCCAACTTAGCCCTGAGGTA GCTATGACCTCACTCTATGACCCTGACCCTGCCCCACCCGGTGTGGAGGATGGNCACCCC ATGCCCCCG >OriGene 3' read for NM_004716 unedited
GTATAGCTATGNNACCGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTTGTTT GGAAGGTTTTTATTTTGGAAAAGCTGTGCAGAAAAAAATCAAGAAAATGTTGCTGTGAAA AGAGAAAAACAAATCTTAAGCATTAAAAAAAATTCAACCAACTAGCTCAGAAGAGGGGAG AAGGCCAAGGTTGAGAGAAGAGTCACAGCCTGTCAGGCAGATAGCTGGCCTCCGGCGGGA AGGCCATTTCCCTGAGCACTTGCAGAGGAAGACAGGGTGGTGGCAGGACTGGAGTGGCAG TGGCTCCCAAGGCTCTCTCCTCCAACATGTGCATCTGCCATCTGCTCTGCAGTCCTGCCG CAGGATTCCCTAGTGAAGCAGCTCAAGCCTGGGGGAGCCGTGTGTATCCCAGCTGTGCCG GCAGCATCATACCAATCGTGGGGGTGGTGAAGGAGCCAGGGGTTCATTCATGGGTGGTTT CTGATCAGGCATCTTGGGAATGGATAATGGAGGCAGCCGCTTTCAGGACAGGCATGTTCA GGGGCTCCTCCCAGCCTCTACCCCGAAGTCCTCTTTCCAAGTGACCCCAGTGATGTTTCC CTTGAGATGCGCTCCTGGCTATGGGAAGGACCCTCTCAACTTATATGTGGAAGGGGGTCC CCCCTGCTTGGGGGACCAAGCACCTGGCTTGGCCCCAAAAAATGAGGGTGGGGGGCAAAC CAAAGGGGGGGCCCAATCCCCGTGCAAACCCTCTTACCAAAACGCCCCGTTGGGTGGGGG CGGAACCTGGGGTCTGAACCACATCTCTTGGGGGAAATCCCCCCCCTTTTTGTTTTAAAA AGGCCCTCACCCCTTTTTGGTGGGGCCCAGGAAGGCCCCCACTTCCCCGAGGTTAGGCCC TCCAAACG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_004716 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004716.2, NP_004707.2 |
| RefSeq Size | 3497 bp |
| RefSeq ORF | 2358 bp |
| Locus ID | 9159 |
| UniProt ID | Q16549 |
| Domains | Peptidase_S8, P_proprotein |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Feb 2014] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203896 | PCSK7 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7) |
CNY 5,752.00 |
|
| RC203896L1 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC203896L2 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), mGFP tagged |
CNY 7,700.00 |
|
| RC203896L3 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), Myc-DDK-tagged |
CNY 8,152.00 |
|
| RC203896L4 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 7 (PCSK7), mGFP tagged |
CNY 8,152.00 |
|
| RG203896 | PCSK7 (tGFP-tagged) - Human proprotein convertase subtilisin/kexin type 7 (PCSK7) |
CNY 7,352.00 |
|
| SC323814 | PCSK7 (untagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7) |
CNY 5,760.00 |
