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CDK2AP1 (NM_004642) Human Untagged Clone
CAT＃: SC117244
CDK2AP1 (untagged)-Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | doc-1; DOC1; DORC1; p12DOC-1; ST19 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117244 sequence for NM_004642 edited (data generated by NextGen Sequencing)
ATGTCTTACAAACCGAACTTGGCCGCGCACATGCCCGCCGCCGCCCTCAACGCCGCTGGG AGTGTCCACTCGCCTTCCACCAGCATGGCAACGTCTTCACAGTACCGCCAGCTGCTCAGT GACTACGGGCCACCGTCCCTAGGCTACACCCAGGGAACTGGGAACAGCCAGGTGCCCCAA AGCAAATACGCGGAGCTGCTGGCCATCATTGAAGAGCTGGGGAAGGAGATCAGACCCACG TACGCAGGGAGCAAGAGTGCCATGGAGAGGCTGAAGCGCGGCATCATTCACGCTAGAGGA CTGGTTCGGGAGTGCTTGGCAGAAACGGAACGGAATGCCAGATCCTAG Clone variation with respect to NM_004642.2 >OriGene 5' read for NM_004642 unedited
GGTTCAAAATTGTAAACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCCTCGTGCC GAATTCGGCACGAGGGCCGCCCGGGGGGATGTCTTACAAACCGAACTTGGCCGCGCACAT GCCCGCCGCCGCCCTCAACGCCGCTGGGAGTGTCCACTCGCCTTCCACCAGCATGGCAAC GTCTTCACAGTACCGCCAGCTGCTCAGTGACTACGGGCCACCGTCCCTAGGCTACACCCA GGGAACTGGGAACAGCCAGGTGCCCCAAAGCAAATACGCGGAGCTGCTGGCCATCATTGA AGAGCTGGGGAAGGAGATCAGACCCACGTACGCAGGGAGCAAGAGTGCCATGGAGAGGCT GAAGCGCGGCATCATTCACGCTAGAGGACTGGTTCGGGAGTGCTTGGCAGAAACGGAACG GAATGCCAGATCCTAGCTGCCTTGTTGGTTTTGAAGGATTTCCATCTTTTTACAAGATGA GAAGTTACAGTTCATCTCCCCTGTTCAGATGAAACCCTTGTTTTCAAAATGGTTACAGTT TCGTTTTTCCTCCCATGGTTCACTTGGCTCTGAACCTACAGTCTCAAAGATTGAGAAAAG ATTTTGCAGTTAATTAGGATTTGCATTTTAAGTAGTTAGGAACTGCCCNAGTTTTTTTTG TTTTTTAAGCATTGATTTAAAAGATGCACGGGAAAGTATCTTACAGCANACTGTAGTTTG CCTCCAAGACACCCATGTCTCCCCTTAAAATCTCTCTTTGGATACATTTTGTACCCATGG GGTGTCTTGNTCCNTTTCATAGCTAATACACTGTAGGGTNATTTGTTTTGACGCATATTG ACAGCACGCTTTACTTAGTAGCCGGTTCCCATTTGCCATACAATGTAAGGNTCTGCTAAT GTACTNCTTTTTTGGCTAAGCATTGCATGACTATTAATGGCTTCAAGTCAATTTT >OriGene 3' read for NM_004642 unedited
NNNNNAAAANNNNNTTTTCTTTAGGANCGCGGNNCCGCATTCTANNGATCGGTTTTTTTT TTTTTTTTTTTTTTTAATAAAAATAAGCTTTATTACATCAAGTAATAAATACATACAAAG ATGCAAACAGTTTTAGTCATTTTCTTCCAGATGTTTTTATCAACTTACAATAAACGCAGA ACTGAGATCTACTTACAGTCTTAGTATGAAAGTGTTCGGGGGTCCTTGTTAGGTTTGGTG GGTTGCTCTTTCTTCTGTATTTATAACTTGTGCATTTTTAAAAATTGACTTTGAAGCACT AATAGTCATGCAAATGCTTAAGCAAAAAAGAAGTACATTAAGCAGAACCTACATTGTATG GCAAATGGGAACCCGCTACTAAGTAAAGCGTGCTGTCAATATGCGTTCAAAACAAAATCC CTACAGTGGTATTTAGCTTATGAAAGGGACAAAGANCACCNTGGGTAACAAATGTTTTCC AAAAGAGAAGATAAAGGGAGACCATGTTGTCTTGGAGCAAACTACCGTTTGCTGTAAAAT AACTTTCCGGGCATCTTTTAAATCAATGCTTAAAAAACAAAAAAACCTGGGCAAGTCCCT ACTTACTAAATGGCAATCCTAATATACCGCAAAACTTTTTTAATCTTTTAACTTGAGGGT CAAAGCCAGTAACCTTGGGAGGAAAAACAAACTGTGACCCTTTGAAAACAAGGTTTATTT TAACGGGGGAAAGAACTGGACCTCTTATTTGGAAAAGAGGGAACCTTTAAAACCCCAGGG CGTAGGATTGGGGTTCCGTCCCTTTTTGGGAAACCTCCCCACAAGCCTTTTAGGGAAAGG CCCCGGTTAACCTCTCAGGGGCTTGGCCCCGTGGACGGGGGGTAATCCTTTCCCCTTTTA AAAGGGGCCCCCTCCCTTTTTTTTTTGGGCCCGGGGGTCCCCACCTGGGGGAACCGGGAG GGGGGCCCTAATTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004642 |
| Insert Size | 1180 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004642.2, NP_004633.1 |
| RefSeq Size | 1627 bp |
| RefSeq ORF | 348 bp |
| Locus ID | 8099 |
| UniProt ID | O14519 |
| Gene Summary | The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer protein (isoform 1). |
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Resources
Other Versions
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| RC204442L2 | Lenti ORF clone of Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), mGFP tagged |
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| RC204442L3 | Lenti ORF clone of Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), Myc-DDK-tagged |
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| RC204442L4 | Lenti ORF clone of Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), mGFP tagged |
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| RG204442 | CDK2AP1 (tGFP-tagged) - Human cyclin-dependent kinase 2 associated protein 1 (CDK2AP1) |
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