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Integrin Linked Kinase (ILK) (NM_004517) Human Untagged Clone
CAT＃: SC117313
ILK (untagged)-Human integrin-linked kinase (ILK), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEL-S-28; ILK-1; ILK-2; P59; p59ILK |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004517 edited
ATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTG GACAACACGGAGAACGACCTCAACCAGGGGGACGATCATGGCTTCTCCCCCTTGCACTGG GCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATC AATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGT GATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACATGGG AATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTG GCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCC AAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAAC CGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGA ACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAAC GAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAG GTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCC CGGCTCAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCA CCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCATATGGATCCCTCTACAATGTA CTACATGAAGGCACCAATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGAC ATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTC AATAGCCGTAGTGTAATGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTC AAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGCT CTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTG CTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATT GGAATGAAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCAT GTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGAC ATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAG >OriGene 5' read for NM_004517 unedited
GGTTCANGATTATGTAATCCGATTTCACTATAGGGCGGACGCCCAATTCGCACGAGGCTC AGGCTTTCCCATCCAGGGACTCGGGGCCCCGACGCTGCTATGGACGACATTTTCACTCAG TGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTC AACCAGGGGGACGATCATGGCTTCTCCCCCTTTTTTTGGGCCTGCCGAGAGGGCCGCTCT GCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGAT GACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTATTG CAGTACAAGGCAGACATCAATGCAGTGAATGAACATGGGAATGTGCCCCTGCACTATGCC TGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGC ATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTT CTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCCATACAAGGACAC ATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGG CATTGACTTCAAACAGCTTAACTTTCTGACGAAGCTCAACGAGAATCACTCCTGGAGAGC TATGGAAAGGGCCGCTTGCCAGGTCAATGACATTGTCGCGAAAGTGCTGAAGGTTCCAGC ACTGGAGTACAAGGAAACACCAGGGCCTTCAATGAAAAGTGTCCCCGGCTTCAAGATTTT CTCGCTTCCAATGTGCTCCCAGCGCTAGGTGCCTGCCAATCTCCACCTGGTTCTCATCCT ATCTCATACACACTGGATGCCTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004517 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004517.2, NP_004508.1 |
| RefSeq Size | 1817 bp |
| RefSeq ORF | 1359 bp |
| Locus ID | 3611 |
| UniProt ID | Q13418 |
| Domains | pkinase, TyrKc, ANK, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Endometrial cancer, Focal adhesion, PPAR signaling pathway |
| Gene Summary | This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] Transcript Variant: This variant (1) encodes isoform 1. Variants 1, 2, and 3 encode the same isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Preservation of human limbal epithelial progenitor cells on carbodiimide cross-linked amniotic membrane via integrin-linked kinase-mediated Wnt activation
,Ma, DH;Chen, HC;Ma, KS;Lai, JY;Yang, U;Yeh, LK;Hsueh, YJ;Chu, WK;Lai, CH;Chen, JK;,
Acta Biomater
,PubMed ID 26612415
[ILK]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201544 | ILK (Myc-DDK-tagged)-Human integrin-linked kinase (ILK), transcript variant 1 |
CNY 5,488.00 |
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| RC201544L1 | Lenti ORF clone of Human integrin-linked kinase (ILK), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
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| RC201544L2 | Lenti ORF clone of Human integrin-linked kinase (ILK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
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| RC201544L3 | Lenti ORF clone of Human integrin-linked kinase (ILK), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201544L4 | Lenti ORF clone of Human integrin-linked kinase (ILK), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG201544 | ILK (tGFP-tagged) - Human integrin-linked kinase (ILK), transcript variant 1 |
CNY 7,088.00 |
|
| SC323933 | ILK (untagged)-Human integrin-linked kinase (ILK), transcript variant 1 |
CNY 5,488.00 |
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