United States
Germany
Japan
United Kingdom
China
EAAT3 (SLC1A1) (NM_004170) Human Untagged Clone
CAT＃: SC117563
SLC1A1 (untagged)-Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1)
CNY 3,912.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DCBXA; EAAC1; EAAT3; SCZD18 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117563 sequence for NM_004170 edited (data generated by NextGen Sequencing)
ATGGGGAAACCGGCGAGGAAAGGATGCGAGTGGAAGCGCTTCCTGAAGAATAACTGGGTG TTGCTGTCCACCGTGGCCGCGGTGGTGCTAGGCATTACCACAGGAGTCTTGGTTCGAGAA CACAGCAACCTCTCAACTCTAGAGAAATTCTACTTTGCTTTTCCTGGAGAAATTCTAATG CGGATGCTGAAACTCATCATTTTGCCATTAATTATATCCAGCATGATTACAGGTGTTGCT GCACTGGATTCCAACGTATCCGGAAAAATTGGTCTGCGCGCTGTCGTGTATTATTTCTGT ACCACTCTCATTGCTGTTATTCTAGGTATTGTGCTGGTGGTGAGCATCAAGCCTGGTGTC ACCCAGAAAGTGGGTGAAATTGCGAGGACAGGCAGCACCCCTGAAGTCAGTACGGTGGAT GCCATGTTAGATCTCATCAGGAATATGTTCCCTGAGAATCTTGTCCAGGCCTGTTTTCAG CAGTACAAAACTAAGCGTGAAGAAGTGAAGCCTCCCAGCGATCCAGAGATGAACATGACA GAAGAGTCCTTCACAGCTGTCATGACAACTGCAATTTCCAAGAACAAAACAAAGGAATAC AAAATTGTTGGCATGTATTCAGATGGCATAAACGTCCTGGGCTTGATTGTCTTTTGCCTT GTCTTTGGACTTGTCATTGGAAAAATGGGAGAAAAGGGACAAATTCTGGTGGATTTCTTC AATGCTTTGAGTGATGCAACCATGAAAATCGTTCAGATCATCATGTGTTATATGCCACTA GGTATTTTGTTCCTGATTGCTGGGAAGATCATAGAAGTTGAAGACTGGGAAATATTCCGC AAGCTGGGCCTTTACATGGCCACAGTCCTGACTGGGCTTGCAATCCACTCCATTGTAATT CTCCCGCTGATATATTTCATAGTCGTACGAAAGAACCCTTTCCGATTTGCCATGGGAATG GCCCAGGCTCTCCTGACAGCTCTCATGATCTCTTCCAGTTCAGCAACACTGCCTGTCACC TTCCGCTGTGCTGAAGAAAATAACCAGGTGGACAAGAGGATCACTCGATTCGTGTTACCC GTTGGTGCAACAATCAACATGGATGGGACCGCGCTCTATGAAGCAGTGGCAGCGGTGTTT ATTGCACAGTTGAATGACCTGGACTTGGGCATTGGGCAGATCATCACCATCAGTATCACG GCCACATCTGCCAGCATCGGAGCTGCTGGCGTGCCCCAGGCTGGCCTGGTGACCATGGTG ATTGTGCTGAGTGCCGTGGGCCTGCCCGCCGAGGATGTCACCCTGATCATTGCTGTCGAC TGGCTCCTGGACCGGTTCAGGACCATGGTCAACGTCCTTGGTGATGCTTTTGGGACGGGC ATTGTGGAAAAGCTCTCCAAGAAGGAGCTGGAGCAGATGGATGTTTCATCTGAAGTCAAC ATTGTGAATCCCTTTGCCTTGGAATCCACAATCCTTGACAACGAAGACTCAGACACCAAG AAGTCTTATGTCAATGGAGGCTTTGCAGTAGACAAGTCTGACACCATCTCATTCACCCAG ACCTCACAGTTCTAG Clone variation with respect to NM_004170.5 1110 t=>c >OriGene 5' read for NM_004170 unedited
AGCTCTGGATTTTGTAATACGACTCACTATAGGGCGGCCGACGAATTCGCACGAGGCGAC AGCCATGGNGGAAACCGGCGAGGAAAGGATGCGAGTGGAAGCGCTTCCTGAAGAATAACT GGGTGTTGCTGTCCACCGTGGCCGCGGTGGTGCTAGGCATTACCACAGGAGTCTTGGTTC GAGAACACAGCAACCTCTCAACTCTAGAGAAATTCTACTTTGCTTTTCCTGGAGAAATTC TAATGCGGATGCTGAAACTCATCATTTTGCCATTAATTATATCCAGCATGATTACAGGTG TTGCTGCACTGGATTCCAACGTATCCGGAAAAATTGGTCTGCGCGCTGTCGTGTATTATT TCTGTACCACTCTCATTGCTGTTATTCTAGGTATTGTGCTGGTGGTGAGCATCAAGCCTG GTGTCACCCAGAAAGTGGGTGAAATTGCGAGGACAGGCAGCACCCCTGAAGTCAGTACGG TGGATGCCATGTTAGATCTCATCAGGAATATGTTCCCTGAGAATCTTGTCCAGGCCTGTT TTCAGCAGTACAAAACTAAGCGTGAAGAAGTGAAGCCTCCCAGCGATCCAGAGATGAACA TGACAGAAGAGTCCTTCACAGCTGTCATGACAACTGCAATTTCCAAGAACAAAACAAAGG AATACAAAATTGTTGGCATGTATTCAGATGGCATAAACGTCCTGNGCTTGATTGTCTTTT GCCTTGTCTTTGGACTTGTCATTGGAAAAATGGGAGAAAAGGGACAAATTCTGGTGGATT TCTTCATGCTTTGAGTGATGCAACCATGAAAATCGTTCAGATCATCATGTGTTATATGCC ACTANGTATTTTGTTCCTGATTGCTGGGAAGATCATAGAAGTTNGAGACTGGGGAATATT NCGCAAGCTGGGCCTTTACATGGCC >OriGene 3' read for NM_004170 unedited
CGCGGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTAATTTATATTTAGATTTA TTTCCTATAAACAATAGCAATATTTGCATTTTAAAATTCACATTGAATCATTATTTACTA TTTATGATGTTTACATAACAATTCAGTATCATTATGTTGTAGATTTCAGATGTAGGTCGT CAATACTGAGCACTTATCTACTCTTCTGCTATCTTTGGCACAATTTCTCATTTCTTAAAC ATGAAAGCACAGGTTTAAGTTGGCTACAGAATACTGCAGAAACATGACTATTTTGGATTT CAGTGTAAGTACAAGTTTATGTTAAGCATTATTTACACGATGAGAACTGAAGTACAGACT ATAATAAACTATCTTCATAAATTACCAGAATGACAAGCAGAGGATGTAATGAATAGGGCC AAGATTACTAGTTAGAACAGTCCTCCTGGAGGAGGAGACAAGAGTCTTAGAATGGAACTA TTTCCCCCGGACCACTCATACCAGCTTATGTCGTGGGATTTACTCTGCAACAACCCAGGT TATGGGGAAGCTCTTTTTNTTGCAACGCGGCTTGTTCCACCCATGTGATCTTTATTAAAA CACATTTTACTTGTTACCTTGCCACTGCTATTCCGCGCCTGATAACACATCTGAAGGCAG GCAAAGAACTCGCCTCTTTGAGTTGAATGAACTGGGAACATAAAGCCTTCATCTGGATGA AGCCCCTCCGCCTTTCGTGGAGGCCAGCTTCTTATCCACCCTACGCCAACCGTATTGGGT CCCCCCCAGCCCCCCAATTTTGAACCCTGTAAAGATGGCTAAGCCACCTCGGGTCACACC CTATTACTCTTTGTCTTAAGTCCCTACCTCTGGAAACCTTTACCACTGATTCTTTTCTAG TGGCTATAAAAGGCACCTCTTACATTTACCCACCTGGCTGGATACGGTCTTTATACATTC GAGACCCCTCCTTTCCCCTCGGTTTTTTCCCTTCCTCGCACCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004170 |
| Insert Size | 3370 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004170.4, NP_004161.4 |
| RefSeq Size | 3730 bp |
| RefSeq ORF | 1575 bp |
| Locus ID | 6505 |
| UniProt ID | P43005 |
| Domains | SDF |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Brief Report: Functional Studies and Rare Variant Screening of SLC1A1 /EAAC1 in Males with Obsessive-Compulsive Disorder
,null,
Psychiatric genetics
,PubMed ID 22617815
[SLC1A1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206281 | SLC1A1 (Myc-DDK-tagged)-Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1) |
CNY 3,904.00 |
|
| RC206281L1 | Lenti ORF clone of Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1), Myc-DDK-tagged |
CNY 6,304.00 |
|
| RC206281L2 | Lenti ORF clone of Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1), mGFP tagged |
CNY 5,890.00 |
|
| RC206281L3 | Lenti ORF clone of Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206281L4 | Lenti ORF clone of Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1), mGFP tagged |
CNY 5,890.00 |
|
| RG206281 | SLC1A1 (tGFP-tagged) - Human solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 (SLC1A1) |
CNY 5,504.00 |
