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CDH12 (NM_004061) Human Untagged Clone
CAT＃: SC117606
CDH12 (untagged)-Human cadherin 12, type 2 (N-cadherin 2) (CDH12)
CNY 8,736.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDHB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004061, the custom clone sequence may differ by one or more nucleotides
ATGCTTACAAGGAACTGTTTATCCCTGCTTCTCTGGGTTCTGTTTGATGGAGGTCTCCTAACACCACTAC AACCACAGCCACAGCAGACTTTAGCCACAGAGCCAAGAGAAAATGTTATCCATCTGCCAGGACAACGGTC ACATTTCCAACGTGTTAAACGTGGCTGGGTATGGAATCAATTTTTTGTGCTGGAAGAATACGTGGGCTCC GAGCCTCAGTATGTGGGAAAGCTCCATTCCGACTTAGACAAGGGAGAGGGCACTGTGAAATACACCCTCT CAGGAGATGGCGCTGGCACCGTTTTTACCATTGATGAAACCACAGGGGACATTCATGCAATAAGGAGCCT AGATAGAGAAGAGAAACCTTTCTACACTCTTCGTGCTCAGGCTGTGGACATAGAAACCAGAAAGCCCCTG GAGCCTGAATCAGAATTCATCATCAAAGTGCAGGATATTAATGATAATGAGCCAAAGTTTTTGGATGGAC CTTATGTTGCTACTGTTCCAGAAATGTCTCCTGTGGGTGCATATGTACTCCAGGTCAAGGCCACAGATGC AGATGACCCGACCTATGGAAACAGTGCCAGAGTCGTTTACAGCATTCTTCAGGGACAACCTTATTTCTCT ATTGATCCCAAGACAGGTGTTATTAGAACAGCTTTGCCAAACATGGACAGAGAAGTCAAAGAACAATATC AAGTACTCATCCAAGCCAAGGATATGGGAGGACAGCTTGGAGGATTAGCCGGAACAACAATAGTCAACAT CACTCTCACCGATGTCAATGACAATCCACCTCGATTCCCCAAAAGCATCTTCCACTTGAAAGTTCCTGAG TCTTCCCCTATTGGTTCAGCTATTGGAAGAATAAGAGCTGTGGATCCTGATTTTGGACAAAATGCAGAAA TTGAATACAATATTGTTCCAGGAGATGGGGGAAATTTGTTTGACATCGTCACAGATGAGGATACACAAGA GGGAGTCATCAAATTGAAAAAGCCTTTAGATTTTGAAACAAAGAAGGCATACACTTTCAAAGTTGAGGCT TCCAACCTTCACCTTGACCACCGGTTTCACTCGGCGGGCCCTTTCAAAGACACAGCTACGGTGAAGATCA GCGTGCTGGACGTAGATGAGCCACCGGTTTTCAGCAAGCCGCTCTACACCATGGAGGTTTATGAAGACAC TCCGGTAGGGACCATCATTGGCGCTGTCACTGCTCAAGACCTGGATGTAGGCAGCAGTGCTGTTAGGTAC TTCATAGATTGGAAGAGTGATGGGGACAGCTACTTTACAATAGATGGAAATGAAGGAACCATCGCCACTA ATGAATTACTAGACAGAGAAAGCACTGCGCAGTATAATTTCTCCATAATTGCGAGTAAAGTTAGTAACCC TTTATTGACCAGCAAAGTCAATATACTGATTAATGTCTTAGATGTAAATGAATTTCCTCCAGAAATATCT GTGCCATATGAGACAGCCGTGTGTGAAAATGCCAAGCCAGGACAGATAATTCAGATAGTCAGTGCTGCAG ACCGAGATCTTTCACCTGCTGGGCAACAATTCTCCTTTAGATTATCACCTGAGGCTGCTATCAAACCAAA TTTTACAGTTCGTGACTTCAGAAACAACACAGCGGGGATTGAAACCCGAAGAAATGGATACAGCCGCAGG CAGCAAGAGTTGTATTTCCTCCCTGTTGTAATAGAAGACAGCAGCTACCCTGTCCAGAGCAGCACAAACA CAATGACTATTCGAGTCTGTAGATGTGACTCTGATGGCACCATCCTGTCTTGTAATGTGGAAGCAATTTT TCTACCTGTAGGACTTAGCACTGGGGCGTTGATTGCAATTCTACTATGCATTGTTATACTCTTAGCCATA GTTGTACTGTATGTAGCACTGCGAAGGCAGAAGAAAAAAGACACCCTGATGACCTCTAAAGAAGACATCA GAGACAACGTCATCCATTACGATGATGAAGGAGGTGGGGAGGAAGATACCCAGGCTTTCGACATCGGGGC TCTGAGAAACCCAAAAGTGATTGAGGAGAACAAAATTCGCAGGGATATAAAACCAGACTCTCTCTGTTTA CCTCGTCAGAGACCACCCATGGAAGATAACACAGACATAAGGGATTTCATTCATCAAAGGCTACAGGAAA ATGATGTGGATCCAACTGCCCCACCATACGATTCACTGGCCACATATGCCTACGAAGGGAGTGGGTCCGT GGCAGAGTCCCTCAGCTCTATAGACTCTCTCACCACAGAAGCCGACCAGGACTATGACTATCTGACAGAC TGGGGACCCCGCTTTAAAGTCTTGGCAGACATGTTTGGCGAAGAAGAGAGTTATAACCCTGATAAAGTCA CTTAA >OriGene 5' read for NM_004061 unedited
NGGGTCATATATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGCTTTA TCCGGGTGACTGCATGGCACTGAATTTCTGCATTGAAAGTTCTAACTGACTAAACTGACA TTCTGCACTGCAGCAAGTGACTGTGTCAGGAAAAGCTTAATTTATAAGCAAGTTTCCTGG AGTGAAAACGGCGTTGGAGATAATGATATCTCAGGGCAATTTCTTCTGAAATACATTCAT TCTGCCTTGTATCCAGAGAAAATAAAAGGGAACATGAAAAGATAGTTAATTTCTCATTTT ACCTTTTTAATAATCTATTTGGAGAGTTGTGCATTGCCAAGGCCCCTTTAGATGGAATAT AATACAGCAGAAGCCTTTTCATCAAAAGGATTAATGCCTGCATCATCATTTCTGCAATAA AACAAGAAGCTAAGTGGTGGAGGCCACAGACACCTCAAACCTGGATTCCACAATTCTACG TTAAGTGTTGGAGTTTTTATTACTCTGCTGTAGGAAAGCCTTTGCCAATGCTTACAAGGA ACTGTTTATCCCTGCTTCTCTGGGTTCTGTTTGATGGAGGTCTCCTAACACCACTACAAC CACAGCCACAGCAGACTTTAGCCACAGAGCCAAGAGAAAATGTTATCCATCTGCCAGGAC AACGGTCACATTTCCAACGTGTTAAACGTGGCTGGGTATGGAATCAATTTTTTGTGCTGG AAAGATACGTGGGCTCCGAGCCTCAGTATGTGGGAAAGCTCCATTCCGACTTAGACAAGG NAGAGGNCACTGTGAAATACACCCTCTCCAGAGATGCGCTGGCACCGTTTTTACATTGAT GAAACACAGGGGACATTCATGCCATTAAGAGCCTAGATAGAGAAGAGAAACTTCT >OriGene 3' read for NM_004061 unedited
GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTCTTTTTTTTTTGGAAAAGAAAG TAACATTTTAATGAACAGCTTTAATGTGAACTAATGTTAAGATCAAACATTGTTTCTAGA ATTTGGGACTTACATATTGAACTTGATATTTTCATATTTATTTCAATTTTCTGAAAGGAT AGGATAAACAAATACGTTTTAGCATACAGTTTAAAAAAGAAAAAGAAAACCTTTTGAATT AGAAGAAGGTGGAGATCAGAAAGTGTTCTTCTTTTGTTCTCAAAAGGAATGAGGAGAGTC AGAGTGTCGCTATTGCTTCTTGACATAAAGACGGAGTCTGTTTTATGTCTTTATCTCTGA ATCCCGCAATACCATCACAGCAGAGTGTACTGTACACCACTTTAAATGATAAGAGTTTCA ATAGGCACTTTAGTGGAATTAAGAAAAATCTAACACTCTTCCACCGTGATGCCACATAGC TATCTTCGTTCTAGGTTGTCATGTCAGTAAATTGTATTGAATAGGCCTGAGCTTGTCTCA GTGTGATTGTGAAAAAACAAAACAACAAAACAAAGCAAGTCACATTATAGGATGTATCTC TTGTTGGCAGAATAAACCAAAACTGACACTATGATTAATTTAGTAACTTACTAGAAACCA GGTAATCAAAGGAATCTTGTCCCAAAANAATGTGTGTGTGTGTGTGTGTGTTTGTGTGTG TGTGTGTGTGTGTGTGTGTCTAAAAAAAATTTCTATTAATATTTGGGGTTTCTTTTCCTT TTTAAAAAACCTCCCTCTCGGGTGTATTTAGCCTNCACGACTNCCTTAGTGACTTTACAA GGGTATTACTCTCTTCTTCGNCAACATGTCTGCCAAGACTTAAAGCGGGTCCCCAGTCTG CAGATATNCATAGCCTGGCCGGTTTGGGGGAGAAGAGTCTTAGAGCTGAGGACTCTGCAC GGACCACTCCCTTTAGCTATGTGGCATAATCNTTGTGGGGCATTGGCCCCTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004061 |
| Insert Size | 3850 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004061.2, NP_004052.2 |
| RefSeq Size | 4164 bp |
| RefSeq ORF | 2385 bp |
| Locus ID | 1010 |
| UniProt ID | P55289 |
| Domains | Cadherin_C_term, CA |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1, 2, and 4-8 all encode the same isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208156 | CDH12 (Myc-DDK-tagged)-Human cadherin 12, type 2 (N-cadherin 2) (CDH12) |
CNY 8,720.00 |
|
| RC208156L1 | Lenti ORF clone of Human cadherin 12, type 2 (N-cadherin 2) (CDH12), Myc-DDK-tagged |
CNY 11,120.00 |
|
| RC208156L2 | Lenti ORF clone of Human cadherin 12, type 2 (N-cadherin 2) (CDH12), mGFP tagged |
CNY 11,120.00 |
|
| RC208156L3 | Lenti ORF clone of Human cadherin 12, type 2 (N-cadherin 2) (CDH12), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC208156L4 | Lenti ORF clone of Human cadherin 12, type 2 (N-cadherin 2) (CDH12), mGFP tagged |
CNY 7,700.00 |
|
| RG208156 | CDH12 (tGFP-tagged) - Human cadherin 12, type 2 (N-cadherin 2) (CDH12) |
CNY 6,370.00 |
