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beta 2 Microglobulin (B2M) (NM_004048) Human Untagged Clone
CAT＃: SC117632
B2M (untagged)-Human beta-2-microglobulin (B2M)
CNY 1,200.00
CNY 2,950.00
| Cited in 7 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMD43 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117632 sequence for NM_004048 edited (data generated by NextGen Sequencing)
ATGTCTCGCTCCGTGGCCTTAGCTGTGCTCGCGCTACTCTCTCTTTCTGGCCTGGAGGCT ATCCAGCGTACTCCAAAGATTCAGGTTTACTCACGTCATCCAGCAGAGAATGGAAAGTCA AATTTCCTGAATTGCTATGTGTCTGGGTTTCATCCATCCGACATTGAAGTTGACTTACTG AAGAATGGAGAGAGAATTGAAAAAGTGGAGCATTCAGACTTGTCTTTCAGCAAGGACTGG TCTTTCTATCTCTTGTACTACACTGAATTCACCCCCACTGAAAAAGATGAGTATGCCTGC CGTGTGAACCATGTGACTTTGTCACAGCCCAAGATAGTTAAGTGGGATCGAGACATGTAA Clone variation with respect to NM_004048.2 >OriGene 5' read for NM_004048 unedited
AGATTTCGGATTTTGTAAATCCGNACTTCACTATAGGGCGGCACGCCAATTCGGCACGAG GCAGCATTCGGGCCGAGATGTCTCGCTCCGTGGCCTTAGCTGTGCTCGCGCTACTCTCTC TTTCTGGCCTGGAGGCTATCCAGCGTACTCCAAAGATTCAGGTTTACTCACGTCATCCAG CAGAGAATGGAAAGTCAAATTTCCTGAATTGCTATGTGTCTGTGTTTCATCCATCCGACA TTGAAGTTGACTTACTGAAGAATGGAGAGAGAATTGAAAAAGTGGAGCATTCAGACTTGT CTTTCAGCAAGGACTGGTCTTTCTATCTCTTGTACTACACTGAATTCACCCCCACTGAAA AAGATGAGTATGCCTGCCGTGTGAACCATGTGACTTTGTCACAGCCCAAGATAGTTAAGT GGGATCGAGACATGTAAGCAGCATCATGGAGGTTTGAAGATGCCGCATTTGGATTGGATG AATTCCAAATTCTGCTTGCTTGCTTTTTAATATTGATATGCTTATACACTTACACTTTAT GCACAAAATGTAGGGTTATAATAATGTTAACATGGACATGATCTTCTTTATAATTCTACT TTGAGTGCTGTCTCCATGTTTGATGTATCTGAGCAGGTTGCTCCACAGGTAGCTCTAGGA GGGCTGGCAACTTAGAGGTGGGGAGCAGAGAATTCTCTTATCCAACATCAACATCTTGGT CAGATTTGAACTCTTCAATCTCTTGCACTCAAAGCTTGTTAAGATAGTTAAGCGTGCATA AGTTAACTTCCAATTTACATACTCTGCTTAGAATTTGGGGAAAATTTTAGAAATATATTG ACAGGATTATTGGAAATTTGTTATAATGAATGAAACATTTTGTCATATNAGATTCATATT TACTTTCTAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004048 |
| Insert Size | 360 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004048.2, NP_004039.1 |
| RefSeq Size | 987 bp |
| RefSeq ORF | 360 bp |
| Locus ID | 567 |
| UniProt ID | P61769 |
| Domains | ig, IGc1 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Antigen processing and presentation |
| Gene Summary | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014] |
Citations (7)
| The use of this cDNA Clones has been cited in the following citations: |
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Gemcitabine alters the proteasome composition and immunopeptidome of tumour cells
,Gravett, A;Trautwein, N;Stevanović, S;Dalgleish, A;Copier, J;,
OncoImmunology
[B2M]
|
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Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12
,Ball, AK;Beilstein, K;Wittmann, S;Sürün, D;Saul, MJ;Schnütgen, F;Flamand, N;Capelo, R;Kahnt, AS;Frey, H;Schaefer, L;Marschalek, R;Häfner, AK;Steinhilber, D;,
Biochim. Biophys. Acta
,PubMed ID 28257804
[B2M]
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Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase
,Häfner, AK;Beilstein, K;Graab, P;Ball, AK;Saul, MJ;Hofmann, B;Steinhilber, D;,
PLoS ONE
,PubMed ID 27855198
[B2M]
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Position 97 of HLA-B, a residue implicated in pathogenesis of ankylosing spondylitis, plays a key role in cell surface free heavy chain expression
,Chen, L;Shi, H;Yuan, J;Bowness, P;,
Ann. Rheum. Dis.
,PubMed ID 27515058
[B2M]
|
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Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor
,Burvenich, IJ;Farrugia, W;Lee, FT;Catimel, B;Liu, Z;Makris, D;Cao, D;O'Keefe, GJ;Brechbiel, MW;King, D;Spirkoska, V;Allan, LC;Ramsland, PA;Scott, AM;,
MAbs
,PubMed ID 27030023
[B2M]
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IgG1 Allotypes Influence the Pharmacokinetics of Therapeutic Monoclonal Antibodies through FcRn Binding
,Ternant, D;Arnoult, C;Pugnière, M;Dhommée, C;Drocourt, D;Perouzel, E;Passot, C;Baroukh, N;Mulleman, D;Tiraby, G;Watier, H;Paintaud, G;Gouilleux-Gruart, V;,
J. Immunol.
,PubMed ID 26685205
[B2M]
|
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Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia
,Rodrigo T. Calado, Joshua A. Regal, Mark Hills, William T. Yewdell, Leandro F. Dalmazzo, Marco A. Zago, Peter M. Lansdorp, Donna Hogge, Stephen J. Chanock, Elihu H. Estey, Roberto P. Falcão, and Neal S. Young,
PNAS, Jan 2009; 106: 1187 - 1192.
[B2M]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207587 | B2M (Myc-DDK-tagged)-Human beta-2-microglobulin (B2M) |
CNY 1,200.00 |
|
| RC207587L1 | Lenti ORF clone of Human beta-2-microglobulin (B2M), Myc-DDK-tagged |
CNY 3,600.00 |
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| RC207587L2 | Lenti ORF clone of Human beta-2-microglobulin (B2M), mGFP tagged |
CNY 5,890.00 |
|
| RC207587L3 | Lenti ORF clone of Human beta-2-microglobulin (B2M), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC207587L4 | Lenti ORF clone of Human beta-2-microglobulin (B2M), mGFP tagged |
CNY 3,600.00 |
|
| RG207587 | B2M (tGFP-tagged) - Human beta-2-microglobulin (B2M) |
CNY 2,800.00 |
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