SCAP2 (SKAP2) (NM_003930) Human Untagged Clone
CAT#: SC117697
SKAP2 (untagged)-Human src kinase associated phosphoprotein 2 (SKAP2)
CNY 3,656.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC117697 sequence for NM_003930 edited (data generated by NextGen Sequencing)
ATGCCCAACCCCAGCAGCACCTCCTCTCCCTACCCCCTCCCTGAGGAAATTAGGAACCTG TTGGCAGATGTTGAAACATTTGTAGCAGATATACTGAAAGGAGAAAATTTATCCAAGAAA GCAAAGGAAAAGAGAGAATCCCTTATTAAGAAGATAAAAGATGTAAAGTCTATCTATCTT CAGGAATTTCAAGACAAAGGTGATGCAGAAGATGGGGAAGAATATGATGACCCTTTTGCT GGGCCTCCAGACACTATTTCATTAGCCTCAGAACGATATGATAAAGACGATGAAGCCCCC TCTGATGGAGCCCAGTTTCCTCCAATTGCAGCACAAGACCTTCCTTTTGTTCTAAAGGCT GGCTACCTTGAAAAACGCAGAAAAGATCACAGCTTTCTGGGATTTGAATGGCAGAAACGG TGGTGTGCTCTCAGTAAAACGGTATTCTATTATTATGGAAGTGATAAAGACAAACAACAG AAAGGTGAATTTGCAATAGATGGCTACAGTGTCAGAATGAATAACACTCTAAGAAAGGAT GGAAAGAAAGATTGCTGTTTTGAAATCTCTGCTCCTGATAAACGTATATATCAGTTTACA GCAGCTTCTCCCAAAGATGCTGAAGAATGGGTACAGCAGCTGAAATTTGTATTGCAAGAT ATGGAATCTGATATTATTCCTGAGGATTATGATGAGAGAGGAGAATTATATGATGATGTT GATCATCCTCTACCAATAAGCAATCCACTAACAAGCAGTCAACCAATAGATGATGAAATT TATGAAGAACTTCCAGAAGAAGAAGAGGACAGTGCTCCAGTGAAAGTGGAAGAACAAAGG AAGATGAGTCAGGATAGTGTCCATCACACCTCAGGGGATAAGAGCACTGATTATGCTAAT TTTTACCAGGGATTGTGGGATTGTACTGGAGCTTTTTCTGATGAGTTGTCATTTAAGCGT GGTGATGTGATTTACATTCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAA ATGAAGGGAGCCATTGGCTTGGTGCCTAAAGCCTACATAATGGAGATGTATGATATTTGA Clone variation with respect to NM_003930.3 >OriGene 5' read for NM_003930 unedited
CGTCAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCTCGCTGG AGATTCAGTGACTTCCTTGTTGTGAGCCCCGGCCCGGCAGTGTCCCGACTCGTAGCCCCG CTGTTCTTAATCCGGGCCGCTAGCCTGAGTCTAGGTCGCAGCCGCAGCCCCACCCCGTCG GTCACCTTTTCAGCGCAGGTCCTTTCCCCGCACGCCCTGCGCTCCCTAACATGCCCAACC CCAGCAGCACCTCCTCTCCCTACCCCCTCCCTGAGGAAATTAGGAACCTGTTGGCAGATG TTGAAACATTTGTAGCAGATATACTGAAAGGAGAAAATTTATCCAAGAAAGCAAAGGAAA AGAGAGAATCCCTTATTAAGAAGATAAAAGATGTAAAGTCTATCTATCTTCAGGAATTTC AAGACAAAGGTGATGCAGAAGATGGGGAAGAATATGATGACCCTTTTGCTGGGCCTCCAG ACACTATTTCATTAGCCTCAGAACGATATGATAAAGACGATGAAGCCCCCTCTGATGGAG CCCAGTTTCCTCCAATTGCAGCACAAGACCTTCCTTTTGTTCTAAAGGCTGGCTACCTTG AAAAACGCAGAAAAGATCACAGCTTTCTGGGATTTGAATGGCAGAAACGGNTGGGTGTGC TCTCAGTAAAACGGTATTCTATTATTATGGAAGTGATAAAGACAAACAACAGAAAGGTGA ATTTGCAATAGATGGCTACAGTGTCAGAATGAATAACACTCTAAGAAAGGGATGGAAAGA AGATTGCTGTTNTGAAATCTCTGCTCCTGATNAACGTATATATCAGTTTACAGCAGCTTC TCCCAAGATGCTNGAGAATGGGTACAGCAGCTGAAAATTGTATTGCAGATATGGAATCTG ATATTATTCCTGAGGATATGATGAGAGAGGAGAATATTGG >OriGene 3' read for NM_003930 unedited
GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTGAGAGGAGTCTCACTCTGTCG CCCAGGCTGGAGTGCAAAGGAGCGATCTTGGCTAACTGCAACCTCTGCCTACCTTGTTCA AGCATTTCTCGTGCCTTGGCCTCCCAATTACCTGGGACTGCAGGTGAACATTACCACACT TGGCTAATTTTTATTACATACAGGGTTTTACCATGTTGGCCTGGCTGGGAGATTCTTTAT ACCATTTTGTTAGTGGCAGGGTGGTATTTCTTAAGAATTTTTTGCTTCATTAAATTTAAA CCTAAGTCCTGTATAAAATGTTGCCAGGCCCATCATCGCACCAGGATATTTGTACCGTAA AATGCTTTGCATGAGTCATACTTCTGGTACGCACTTCTGTTGCAGGCGACAGCTCACTGC CATTTGCAACTTCATCATTTTTTCTTTCTTGCGGCTGTACTTAATACGAATCAAATGTGT GAAAATACCTAATGACAATACAGTCGTCTATAACGTTTGAACATTCTTTTACATTCTTTG GTTATCAACCACATTCTTCAGCATCTACCAAAAAAGACTCGCATGATACACTAAATTTAA AATGCTATGAATTAACTCCTTACTCTCTAAAAATATTCGATGTCCAATGATCAAGAAACT TAGCAATCACCCCGGATTACCTTAGTGCCTACTATGCTTAGCAGACTCTTTGTACCCCTA AAATTGGGATGAATTCTTCCCCCAAATAAATGGGTAAATAAAAACCTTGATTTTTTCTTT GCAAAAACCACAGGTTTAACTTACCGGGCTGGCTTAACTTTACCTAATTTCCCTCCTTAA TTTCACACCAAAGCATTCCTTTACCCCCGTCCGCTCCAAAACGCCTAACCTCATCAATGT TTATAATAAAAGGAAAGGTAGGAGCGGCCACGCGTGCTTAAGACCTCCTTAATCAAGGCT GTGGAATACACAAGATAATCTTTCCAAACT |
Restriction Sites | NotI-NotI |
ACCN | NM_003930 |
Insert Size | 2500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_003930.3, NP_003921.2 |
RefSeq Size | 3984 bp |
RefSeq ORF | 1080 bp |
Locus ID | 8935 |
UniProt ID | O75563 |
Domains | SH3, PH |
Gene Summary | The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206119 | SKAP2 (Myc-DDK-tagged)-Human src kinase associated phosphoprotein 2 (SKAP2) |
CNY 3,656.00 |
|
RC206119L1 | Lenti ORF clone of Human src kinase associated phosphoprotein 2 (SKAP2), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC206119L2 | Lenti ORF clone of Human src kinase associated phosphoprotein 2 (SKAP2), mGFP tagged |
CNY 5,890.00 |
|
RC206119L3 | Lenti ORF clone of Human src kinase associated phosphoprotein 2 (SKAP2), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC206119L4 | Lenti ORF clone of Human src kinase associated phosphoprotein 2 (SKAP2), mGFP tagged |
CNY 5,890.00 |
|
RG206119 | SKAP2 (tGFP-tagged) - Human src kinase associated phosphoprotein 2 (SKAP2) |
CNY 5,256.00 |