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FADD (NM_003824) Human Untagged Clone
CAT＃: SC117739
FADD (untagged)-Human Fas (TNFRSF6)-associated via death domain (FADD)
CNY 2,400.00
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GIG3; MORT1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003824 edited
GAATTCGGCACGAGGCGCTCTTGTCGATTTCCTGTAGTGAATCAGGCACCGGAGTGCAGG TTCGGGGGTGGAATCCTTGGGCCGCTGGGCAAGCGGCGAGACCTGGCCAGGGCCAGCGAG CCGAGGACAGAGGGCGCGCGGAGGGCCGGGCCGCAGCCCCGGCCGCTTGCAGACCCCGCC ATGGACCCGTTCCTGGTGCTGCTGCACTCGGTGTCGTCCAGCCTGTCGAGCAGCGAGCTG ACCGAGCTCAAGTTCCTATGCCTCGGGCGCGTGGGCAAGCGCAAGCTGGAGCGCGTGCAG AGCGGCCTAGACCTCTTCTCCATGCTGCTGGAGCAGAACGACCTGGAGCCCGGGCACACC GAGCTCCTGCGCGAGCTGCTCGCCTCCCTGCGGCGCCACGACCTGCTGCGGCGCGTCGAC GACTTCGAGGCGGGGGCGGCGGCCGGGGCCGCGCCTGGGGAAGAAGACCTGTGTGCAGCA TTTAACGTCATATGTGATAATGTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAA GTCTCAGACACCAAGATCGACAGCATCGAGGACAGATACCCCCGCAACCTGACAGAGCGT GTGCGGGAGTCACTGAGAATCTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCCCAC CTGGTGGGGGCTCTCAGGTCCTGCCAGATGAACCTGGTGGCTGACCTGGTACAAGAGGTT CAGCAGGCCCGTGACCTCCAGAACAGGAGTGGGGCCATGTCCCCGATGTCATGGAACTCA GACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACAGGC ATCTACACAGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCA GCAGGAAGCCAGGCTGAGTGAGCCACAGACCACCTGCTTCTGAACTCAAGCTGCGTTTAT TAATGCCTCTCCCGCACCAGGCCGGGCTTGGGCCCTGCACAGATATTTCCATTTCTTCCT CACTATGACACTGAGCAAGATCTTGTCTCCACTAAATGAGCTCCTGCGGGAGTAGTTGGA AAGTTGGAACCGTGTCCAGCACAGAAGGAATCTGTGCAGATGAGCAGTCACACTGTTACT CCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAGAGGTGGAGA ACTGGGATTTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTC TGCTGCCCCTGCAGTTGGCAGAAAGGATGTTTTGTCCCATTTCCTTGGAGGCCACCGGGA CAGACCTGGACACTAGGGTCAGGCGGGGTGCTGTTGTGGTGGGGAGAGGCATGGCTGGGG TGGGGGTGGGGAGACCTGGTTGGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTC TCCTCTCTGAGACTGCTAAGTAGGGGCAGTGATGGTTGCCAGGACGAATTGAGATAATAT CTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTCTAAATCTTCCTTGTGAGGATT ATGGGTCCTGCAATTCTACAGTTTCTTACTGTTTTGTATCAAAATCACTATCTTTCTGAT AACAGAATTGCCAAGGCAGCGGGATCTCGTATCTTTAAAAAGCAGTCCTCTTATTCCTAA GGTAATCCTATTAAAACACAGCTTTACAACTTCAAAAAAAAAAAAAAAAAAAAAAAAAAA CTCGAC >OriGene 5' read for NM_003824 unedited
TTCAAAATTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCGCTCTT GTCGATTTCCTGTAGTGAATCAGGCACCGGAGTGCAGGTTCGGGGGTGGAATCCTTGGGC CGCTGGGCAAGCGGCGAGACCTGGCCAGGGCCAGCGAGCCGAGGACAGAGGGCGCGCGGA GGGCCGGGCCGCAGCCCCGGCCGCTTGCAGACCCCGCCATGGACCCGTTCCTGGTGCTGC TGCACTCGGTGTCGTCCAGCCTGTCGAGCAGCGAGCTGACCGAGCTCAAGTTCCTATGCC TCGGGCGCGTGGGCAAGCGCAAGCTGGAGCGCGTGCAGAGCGGCCTAGACCTCTTCTCCA TGCTGCTGGAGCAGAACGACCTGGAGCCCGGGCACACCGAGCTCCTGCGCGAGCTGCTCG CCTCCCTGCGGCGCCACGACCTGCTGCGGCGCGTCGACGACTTCGAGGCGGGGGGCGGCG GCCGGNGCCGCGCCTGGGGAAGAAGACCTGTGTGCAGCATTTAACGTCATATGTGATAAT GTGGGGAAAGATTGGAGAAGGCTGGCTCGTCAGCTCAAAGTCTCAGACACCAAGATCGAC AGCATCGAGGACAGATACCCCCGCAACCTGACAGAGCGTGTGCGGGGAGTCACTGAGAAT CTGGAAGAACACAGAGAAGGAGAACGCAACAGTGGCCACCTGGGTGGGGGCTTCTCAGGT CCTGCCAGATGAACCTGGNTGGCTGACCTGGACCCAAGAGGTTCCAGCAGGGCCCGTGAC CTCAGACAGGAGGATTGGGGCCATGTCCCCCGATGTCATGGGACTCAGACGCATCACCTC CCAACGCCCCTGATGGGCCGCTGCTTTGGCCCTGGTGGACCACAGCATCTACCAGNCGGC ATTTTTGGTCTCTCCCAGGAAGGGTACCCACCCTTGGGAAGACCCAGCAGAGCC >OriGene 3' read for NM_003824 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTGAAGTTG TAAAGCTGTGTTTTAATAGGATTACCTTAGGAATAAGAGGACTGCTTTTTAAAGATACGA GATCCCGCTGCCTTGGCAATTCTGTTATCAGAAAGATAGTGATTTTGATACAAAACAGTA AGAAACTGTAGAATTGCAGGACCCATAATCCTCACAAGGAAGATTTAAAGAGTGCTGTGT GTCAATCACTCATCAGCACCTCACAGATATTATCTCAATTCGTCCTGGCAACCATCACTG CCCCTACTTAGCAGTCTCAGAGAGGAGACTCAACTCACACAGGGGCCAAGAGCTGGACCA CGGCCAACCAGGTCTCCCCACCCCCACCCCAGCCATGCCTTTCCCCACCACAACAGCACC CCGCCTGACCCTAGTGTCCAGGTCTGTCCCGGTGGCCTCCAAGGAAATGGGACAAAACAT CCTTTCTGCCAACTGCAGGGGCAGCAGAACGCCACAGTGGTTGAGCATGGGCTCTGGTGA AGGATGGCGGGGGTTCAAATCCCAGTTCTCCACCTCTCTGCTTCGCTCCGATTCCTGGGC CTCTGAGCTGGTCTCCTCCGCTGTGGAGTAACAGTGTGACTGCTTATCTGCACAGATTCC CTTTGTGCTGGACACGGTTCCAACTTTCCAACTACTCCCGCCAGAGCTTATTTATTGGAA ACCAGATCTTGGCTCAATGGCTTAGTGAGGGAGAAATGGAAATTTTTGTGCAGGGCCCAA CCCCGGCCTGGTGCGGGGAAGGGCTTTTATAAACCCAGCTTGATTTCAAAACAGGGGGGC TGTGGCTCACTTACACCGGCTTTCTGCTGGGGCTTACAAGGGCTGGGCTCCTTCTGGAAA AAACCCAATCCCAGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003824 |
| Insert Size | 1970 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003824.2, NP_003815.1 |
| RefSeq Size | 1873 bp |
| RefSeq ORF | 627 bp |
| Locus ID | 8772 |
| UniProt ID | Q13158 |
| Domains | DEATH, DED |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Apoptosis, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201805 | FADD (Myc-DDK-tagged)-Human Fas (TNFRSF6)-associated via death domain (FADD) |
CNY 2,400.00 |
|
| RC201805L1 | Lenti ORF clone of Human Fas (TNFRSF6)-associated via death domain (FADD), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201805L2 | Lenti ORF clone of Human Fas (TNFRSF6)-associated via death domain (FADD), mGFP tagged |
CNY 5,890.00 |
|
| RC201805L3 | Lenti ORF clone of Human Fas (TNFRSF6)-associated via death domain (FADD), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201805L4 | Lenti ORF clone of Human Fas (TNFRSF6)-associated via death domain (FADD), mGFP tagged |
CNY 4,800.00 |
|
| RG201805 | FADD (tGFP-tagged) - Human Fas (TNFRSF6)-associated via death domain (FADD) |
CNY 4,000.00 |
