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S1P (MBTPS1) (NM_003791) Human Untagged Clone
CAT＃: SC117763
MBTPS1 (untagged)-Human membrane-bound transcription factor peptidase, site 1 (MBTPS1)
CNY 7,336.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PCSK8; S1P; SEDKF; SKI-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003791, the custom clone sequence may differ by one or more nucleotides
ATGAAGCTTGTCAACATCTGGCTGCTTCTGCTCGTGGTTTTGCTCTGTGGGAAGAAACATCTGGGCGACA GACTGGAAAAGAAATCTTTTGAAAAGGCCCCATGCCCTGGCTGTTCCCACCTGACTTTGAAGGTGGAATT CTCATCAACAGTTGTGGAATATGAATATATTGTGGCTTTCAATGGATACTTTACAGCCAAAGCTAGAAAT TCATTTATTTCAAGTGCCCTGAAGAGCAGTGAAGTAGACAATTGGAGAATTATACCTCGAAACAATCCAT CCAGTGACTACCCTAGTGATTTTGAGGTGATTCAGATAAAAGAAAAACAGAAAGCGGGGCTGCTAACACT TGAAGATCATCCAAACATCAAACGGGTCACGCCCCAACGAAAAGTCTTTCGTTCCCTCAAGTATGCTGAA TCTGACCCCACAGTACCCTGCAATGAAACCCGGTGGAGCCAGAAGTGGCAATCATCACGTCCCCTGCGAA GAGCCAGCCTCTCCCTGGGCTCTGGCTTCTGGCATGCTACGGGAAGGCATTCGAGCAGACGGCTGCTGAG AGCCATCCCGCGCCAGGTTGCCCAGACACTGCAGGCAGATGTGCTCTGGCAGATGGGATATACAGGTGCT AATGTAAGAGTTGCTGTTTTTGACACTGGGCTGAGCGAGAAGCATCCCCACTTCAAAAATGTGAAGGAGA GAACCAACTGGACCAACGAGCGAACGCTGGACGATGGGTTGGGCCATGGCACATTCGTGGCAGGTGTGAT AGCCAGCATGAGGGAGTGCCAAGGATTTGCTCCAGATGCAGAACTTCACATTTTCAGGGTCTTTACCAAT AATCAGGTATCTTACACATCTTGGTTTTTGGACGCCTTCAACTATGCCATTTTAAAGAAGATCGACGTGT TAAACCTCAGCATCGGCGGCCCGGACTTCATGGATCATCCGTTTGTTGACAAGGTGTGGGAATTAACAGC TAACAATGTAATCATGGTTTCTGCTATTGGCAATGACGGACCTCTTTATGGCACTCTGAATAACCCTGCT GATCAAATGGATGTGATTGGAGTAGGCGGCATTGACTTTGAAGATAACATCGCCCGCTTTTCTTCAAGGG GAATGACTACCTGGGAGCTACCAGGAGGCTACGGTCGCATGAAACCTGACATTGTCACCTATGGTGCTGG CGTGCGGGGTTCTGGCGTGAAAGGGGGGTGCCGGGCCCTCTCAGGGACCAGTGTTGCTTCTCCAGTGGTT GCAGGTGCTGTCACCTTGTTAGTGAGCACAGTCCAGAAGCGTGAGCTGGTGAATCCCGCCAGTATGAAGC AGGCCCTGATCGCGTCAGCCCGGAGGCTCCCCGGGGTCAACATGTTTGAGCAAGGCCACGGCAAGCTCGA TCTGCTCAGAGCCTATCAGATCCTCAACAGCTACAAGCCACAGGCAAGTTTGAGCCCCAGCTACATAGAT CTGACTGAGTGTCCCTACATGTGGCCCTACTGCTCCCAGCCCATCTACTATGGAGGAATGCCGACAGTTG TTAATGTCACCATCCTCAACGGCATGGGAGTCACAGGAAGAATTGTAGATAAGCCTGACTGGCAGCCCTA TTTGCCACAGAACGGAGACAACATTGAAGTTGCCTTCTCCTACTCCTCGGTCTTATGGCCTTGGTCGGGC TACCTGGCCATCTCCATTTCTGTGACCAAGAAAGCGGCTTCCTGGGAAGGCATTGCTCAGGGCCATGTCA TGATCACTGTGGCTTCCCCAGCAGAGACAGAGTCAAAAAATGGTGCAGAACAGACTTCAACAGTAAAGCT CCCCATTAAGGTGAAGATAATTCCTACTCCCCCGCGAAGCAAGAGAGTTCTCTGGGATCAGTACCACAAC CTCCGCTATCCACCTGGCTATTTCCCCAGGGATAATTTAAGGATGAAGAATGACCCTTTAGACTGGAATG GTGATCACATCCACACCAATTTCAGGGATATGTACCAGCATCTGAGAAGCATGGGCTACTTTGTAGAGGT CCTCGGGGCCCCCTTCACGTGTTTTGATGCCAGTCAGTATGGCACTTTGCTGATGGTGGACAGTGAGGAG GAGTACTTCCCTGAAGAGATCGCCAAGCTCCGGAGGGACGTGGACAACGGCCTCTCGCTCGTCATCTTCA GTGACTGGTACAACACTTCTGTTATGAGAAAAGTGAAGTTTTATGATGAAAACACAAGGCAGTGGTGGAT GCCGGATACCGGAGGAGCTAACATCCCAGCTCTGAATGAGCTGCTGTCTGTGTGGAACATGGGGTTCAGC GATGGCCTGTATGAAGGGGAGTTCACCCTGGCCAACCATGACATGTATTATGCGTCAGGGTGCAGCATCG CGAAGTTTCCAGAAGATGGCGTCGTGATAACACAGACTTTCAAGGACCAAGGATTGGAGGTTTTAAAGCA GGAAACAGCAGTTGTTGAAAACGTCCCCATTTTGGGACTTTATCAGATTCCAGCTGAGGGTGGAGGCCGG ATTGTACTGTATGGGGACTCCAATTGCTTGGATGACAGTCACCGACAGAAGGACTGCTTTTGGCTTCTGG ATGCCCTCCTCCAGTACACATCGTATGGGGTGACACCGCCTAGCCTCAGTCACTCTGGGAACCGCCAGCG CCCTCCCAGTGGAGCAGGCTCAGTCACTCCAGAGAGGATGGAAGGAAACCATCTTCATCGGTACTCCAAG GTTCTGGAGGCCCATTTGGGAGACCCAAAACCTCGGCCTCTACCAGCCTGTCCACGCTTGTCTTGGGCCA AGCCACAGCCTTTAAACGAGACGGCGCCCAGTAACCTTTGGAAACATCAGAAGCTACTCTCCATTGACCT GGACAAGGTGGTGTTACCCAACTTTCGATCGAATCGCCCTCAAGTGAGGCCCTTGTCCCCTGGAGAGAGC GGCGCCTGGGACATTCCTGGAGGGATCATGCCTGGCCGCTACAACCAGGAGGTGGGCCAGACCATTCCTG TCTTTGCCTTCCTGGGAGCCATGGTGGTCCTGGCCTTCTTTGTGGTACAAATCAACAAGGCCAAGAGCAG GCCGAAGCGGAGGAAGCCCAGGGTGAAGCGCCCGCAGCTCATGCAGCAGGTTCACCCGCCAAAGACCCCT TCGGTGTGA >OriGene 5' read for NM_003791 unedited
GGGCACATTTGTATACGACTCCTATAGGCGGCNCGCGATTCGGCACGAGGCGGCGGAGCT GAGGCTCCCAGCTGTGGGCCTCGCTGGCCCGGTCGCCCAGTCTCGCGAGAGTTGGGAGTA AACAGCCCCGAATGGAGTGCCCAGGCGTGTTCGCCGCGGAGGCGCCGTTATCCCGGGCCC GCCGGCCCTGAGCTCCCGGCGGCGCAGATTGGCTCACAGTGGTTGATTGATCAACCCCAT TGGACGTTGGTTCTGTGGTACAAATGGAGTACAGGACTCAGTCGTCACGGCCTGAGTGAG AGAAGCCTTATTTCCAAGATGGAGAAGAAGCGGAGAAAGAAATGAAAGCCTCTCTTCAGG CTGAACCACAAAAGGCCATGGGATTTAACTTTTATTTATGTTGGGCAAGACTGTAAGATG GCTGATTAGTAATGTTGCAGCTTTTAGCTGAAACAAAAATTCACTTTTAATCAAGAAGAA AAAAGTGTGATTTGAATATATGCAATTTTATGATCATATTCGCTTGTGACCATGAAGCTT GTCAACATCTGGCTGCTTCTGCTCGTGGTTTTGCTCTGTGGGAAGAAACATCTGGGCGAC AGACTGGAAAAGAAATCTTTTGAAAAGGCCCCATGCCCTGNCTGTTCCCACCTGACTNTG AAGGTGGAATTCTCATCAACAGTTGTGGAATATGAATATATTGTGGCTTTCAATGGATAC TNTACAGCCAAAGCTAGAAATTCATTTATTTCAAGTGCCCCTGAGAGCAGTGAAGTAGAC AATTGGAGAAATATACCTCGAANCAATNCATCCAGTGACTACCCTAGTGATTTTGAGGGT GATCAGATAAAGAAAAACAGAAAGCGGGCTGCTAACACTTGAAGACATNCAANCATCAAC CGGTCACGCCCC >OriGene 3' read for NM_003791 unedited
TGCACCGCGGCACGCAATCTAGCATCGAGTTTTTTTTTTTTTTTTTTAAGCTTCAAACGG GTAATACATATTTATTGAAAATTTTCTTCACCGACAATGGTGAAATCAAGACCTCAAATT ACAAAACATGGCGGCAGGTGATACTTACAAAAATAAAGCGAAGGTCTATGTTTTACAGAT TAGTGCATGTTACCTTTAAATCTCAGCCTGTCCTGCCATTAAAAAGCATCATGGTATCTA TGTTGTCTCTTATGATGGATTACCCAAAAAACTGCATTTCACTGACAAAAAAAATATCTT TGCTTGTAAATAGCACAATTTTTTAAAGCGACTTTTTTCATCAATAAATATAGAAAATAT CCTTCACCACTCGCCCTTAACCTTGCTCACGTTTGTCTTATTTGTCCGCAAAGCCATCCC TTTCCCTGTTGTATCACACTGCTCACACTCTCTTTTCTACTTCCACCTATTCTTTGGTGT CATCACTCTTTCGACCGACAATTCTTACCGGTGGCTCAATCACTAAATTCCTTCTGTCGG TATCTTTAAGATTCACTCCTCATGTTCATCTACCCCTCTGTACTTTAAAGATGCTCCTTC CTGCTTAATATATCTTATCTATTTTTATCACATAAACTGTTTTATTTTAATACTTTCTAT AACCACGCTCCGTTACACCATTTTTTGTTCCTATCTTATATGCCACATCTTTGGTTCCTC CCCGCCCACTCCTTCTTCCCTTTTTATCTCTCTAGGGTATTATTTTCAGTCGTACCTCAT TCATTTGCACCCTCCCCTCCTCCTCCCATTGATTTTCCTCTCTTATCCCCTTCCCCCGAC TTCTCAATATTTTTATTCCCGCATTAGCCCTTATTTCTTTCGTTTTTTCTTCACTCTCTC ACCGTATATAATCGACTTCCCTTCTCTTTTTTTATTTATTCTCAACTCCCCACACGTGAA TACCCTGTCCCTACCACTGGTCATAGTTTATTCCCTTGTTTATTATCTTTCTCTCCCCAA TTCACATATTCATTCTACTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003791 |
| Insert Size | 4650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003791.2, NP_003782.1 |
| RefSeq Size | 4354 bp |
| RefSeq ORF | 3159 bp |
| Locus ID | 8720 |
| UniProt ID | Q14703 |
| Domains | Peptidase_S8 |
| Protein Families | Druggable Genome, Protease, Transcription Factors, Transmembrane |
| Gene Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212265 | MBTPS1 (Myc-DDK-tagged)-Human membrane-bound transcription factor peptidase, site 1 (MBTPS1) |
CNY 7,328.00 |
|
| RC212265L1 | Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 1 (MBTPS1), Myc-DDK-tagged |
CNY 9,728.00 |
|
| RC212265L2 | Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 1 (MBTPS1), mGFP tagged |
CNY 12,350.00 |
|
| RC212265L3 | Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 1 (MBTPS1), Myc-DDK-tagged |
CNY 9,728.00 |
|
| RC212265L4 | Lenti ORF clone of Human membrane-bound transcription factor peptidase, site 1 (MBTPS1), mGFP tagged |
CNY 9,728.00 |
|
| RG212265 | MBTPS1 (tGFP-tagged) - Human membrane-bound transcription factor peptidase, site 1 (MBTPS1) |
CNY 8,928.00 |
