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PRSS8 (NM_002773) Human Untagged Clone
CAT＃: SC118401
PRSS8 (untagged)-Human protease, serine, 8 (PRSS8)
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP1; PROSTASIN |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118401 sequence for NM_002773 edited (data generated by NextGen Sequencing)
ATGGCCCAGAAGGGGGTCCTGGGGCCTGGGCAGCTGGGGGCTGTGGCCATTCTGCTCTAT CTTGGATTACTCCGGTCGGGGACAGGAGCGGAAGGGGCAGAAGCTCCCTGCGGTGTGGCC CCCCAAGCACGCATCACAGGTGGCAGCAGTGCAGTCGCCGGTCAGTGGCCCTGGCAGGTC AGCATCACCTATGAAGGCGTCCATGTGTGTGGTGGCTCTCTCGTGTCTGAGCAGTGGGTG CTGTCAGCTGCTCACTGCTTCCCCAGCGAGCACCACAAGGAAGCCTATGAGGTCAAGCTG GGGGCCCACCAGCTAGACTCCTACTCCGAGGACGCCAAGGTCAGCACCCTGAAGGACATC ATCCCCCACCCCAGCTACCTCCAGGAGGGCTCCCAGGGCGACATTGCACTCCTCCAACTC AGCAGACCCATCACCTTCTCCCGCTACATCCGGCCCATCTGCCTCCCTGCAGCCAACGCC TCCTTCCCCAACGGCCTCCACTGCACTGTCACTGGCTGGGGTCATGTGGCCCCCTCAGTG AGCCTCCTGACGCCCAAGCCACTGCAGCAACTCGAGGTGCCTCTGATCAGTCGTGAGACG TGTAACTGCCTGTACAACATCGACGCCAAGCCTGAGGAGCCGCACTTTGTCCAAGAGGAC ATGGTGTGTGCTGGCTATGTGGAGGGGGGCAAGGACGCCTGCCAGGGTGACTCTGGGGGC CCACTCTCCTGCCCTGTGGAGGGTCTCTGGTACCTGACGGGCATTGTGAGCTGGGGAGAT GCCTGTGGGGCCCGCAACAGGCCTGGTGTGTACACTCTGGCCTCCAGCTATGCCTCCTGG ATCCAAAGCAAGGTGACAGAACTCCAGCCTCGTGTGGTGCCCCAAACCCAGGAGTCCCAG CCCGACAGCAACCTCTGTGGCAGCCACCTGGCCTTCAGCTCTGCCCCAGCCCAGGGCTTG CTGAGGCCCATCCTTTTCCTGCCTCTGGGCCTGGCTCTGGGCCTCCTCTCCCCATGGCTC AGCGAGCACTGA Clone variation with respect to NM_002773.3 >OriGene 5' read for NM_002773 unedited
AGCATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGGGTGACTCG TCCACACTGCTCGCTTCGGATACTCCAGGCGTCTCCCGTTGCGGCCGCTCCCTGCCTTAG AGGCCAGCCTTGGACACTTGCTGCCCCTTTCCAGCCCGGATTCTGGGATCCTTCCCTCTG AGCCAACATCTGGGTCCTGCCTTCGACACCACCCCAAGGCTTCCTACCTTGCGTGCCTGG AGTCTGCCCCAGGGGCCCTTGTCCTGGGCCATGGCCCAGAAGGGGGTCCTGGGGCCTGGG CAGCTGGGGGCTGTGGCCATTCTGCTCTATCTTGGATTACTCCGGTCGGGGACAGGAGCG GAAGGGGCAGAAGCTCCCTGCGGTGTGGCCCCCCAAGCACGCATCACAGGTGGCAGCAGT GCAGTCGCCGGTCAGTGGCCCTGGCAGGTCAGCATCACCTATGAAGGCGTCCATGTGTGT GGTGGCTCTCTCGTGTCTGAGCAGTGGGTGCTGTCAGCTGCTCACTGCTTCCCCAGCGAG CACCACAAGGAAGCCTATGAGGTCAAGCTGGGGGCCCACCAGCTAGACTCCTACTCCGAG GACGCCAAGGTCAGCACCCTGAAGGACATCATCCCCCACCCCAGCTACCTCCAGGAGGGC TCCCAGGGCGACATTGCACTCCTCCAACTCAGCAGACCCATCACCTTCTCCCGCTACATC CGGCCCATCTGCCTCCCTGCAGCCAACGCCTNCTTCCCCACGGCCTCCACTGCACTGTCA CTGGCTGGGGTCATGTGGCCCCCTCAGTGAGCCTCCTGACGCCCAAGCCACTGCAGCAAC TCGAGGTGCCTCTGATCAGTCGTGAGACGTGTAACTTGCTGTACACATCGACGCCAACCC TGAGACCGCACTTTGCCCAGAGACATGGTGTGTGCTGGCTATGTGAGGGGGCAG >OriGene 3' read for NM_002773 unedited
ATCTTGNCCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGTGCTCAAACA TTTTAATCATTTCTGCCCTGTTACTCCCACCCCAAATCCAAGCGCCAGCCCAGTTCCGGT GGGGGCTCAGTCCTCCGGAGTCCAGGAGTCAGGGCTCGGGGGCGCTCAGCGGCCAGTGGG CAAGATTGGGGCCTTTCCTGTCCTCGAAGCTGCACAAAGGTGGCCCCAGCCCAGAACACA GGGAGAGGGCAGAGAGATGTGCTCATCAGTCTGGGCAGGCGGGCCGGGAGCAGTCTTCCA GAAACAGGTGGGAGCCAGGGCTCATTTTCATAGCCAAGGGTCCCAGGAGCTCCCCAGGAG CTCGGCCAATGGGCTGGTCCATGGTGGGTGAGGGGCCAGAGGCTCTGGCCATTGCTACAG GCAGTAAAACTCCTGACTCTCAGTGATGGTCCCAAAAAGCACACCCAGAAGAATGGGCTC AAAGATCAAGATGGGGCCCCAGCCTCCCGCAGAGTCCTGAAGGAAGGAGTGGCTCAAGTC AGGCCCTGGGTCCAAGGCCATCAGGGAAGGACCANGCTCCTGTCCTTGAGTGTGATGCAT CCATCCTGGAAGTAGGGCCAGCTCAGTGCTCGCTGAGCCCTGGGAAGAGAGGCCCAAAGC CGGCCCCAGAGCCAGAAAAGATGGGCCTCAGCAAGCCCTGGGCTGGGGCANAACTGAAGC CACGTGGCTGCACANAAGTTGCTGTCGGGCTGGGACTCCTGGTTTGGGGCACCCACCAGC CTGGAGTTTTGTCACCTTGCTTTGGATCCACGAGGCCTACCTGGAAGGCCCAGGGGTCCC CCAGGCCTGTTGGGGGCCCCCAGGCTTTTCCCAGTTAAAATGCCGGCAGGGACCAAAGAC CTCCCCAGGCCGGGAAGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002773 |
| Insert Size | 1770 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002773.2, NP_002764.1 |
| RefSeq Size | 1938 bp |
| RefSeq ORF | 1032 bp |
| Locus ID | 5652 |
| UniProt ID | Q16651 |
| Domains | Tryp_SPc |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
,Drees, L;Königsmann, T;Jaspers, MHJ;Pflanz, R;Riedel, D;Schuh, R;,
PLoS Genet.
,PubMed ID 30601807
[PRSS8]
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| SC320203 | PRSS8 (untagged)-Human protease, serine, 8 (PRSS8) |
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