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Prolyl Endopeptidase (PREP) (NM_002726) Human Untagged Clone
CAT＃: SC118444
PREP (untagged)-Human prolyl endopeptidase (PREP)
CNY 5,208.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PE; PEP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002726 edited
GAATTCGGCACGAGGCTGGCCGTGAGCNGGCCGCCCGCTGCCGCCGGCCGCCCCGCAGCT GCCTGCGCCCCAGCCGCGCCTCGCGGCCAGCCCGGCTAGCTCAGGTCCGCTCCCGGAGCC CGCGCCCCTCCACGCTGCCCCCTGCCTGTCCCCGGCCATGCTGTCCCTTCAGTACCCCGA CGTGTACCGCGACGAGACCGCCGTACAGGATTATCATGGTCATAAAATTTGTGACCCTTA CGCCTGGCTTGAAGACCCCGACAGTGAACAGACTAAGGCCTTTGTGGAGGCCCAGAATAA GATTACTGTGCCATTTCTTGAGCAGTGTCCCATCAGAGGTTTATACAAAGAGAGAATGAC TGAACTATATGATTATCCCAAGTATAGTTGCCACTTCAAGAAAGGAAAACGGTATTTTTA TTTTTACAATACAGGTTTGCAGAACCAGCGAGTATTATATGTACAGGATTCCTTAGAGGG TGAGGCCAGAGTGTTCCTGGACCCCAACATACTGTCTGACGATGGCACAGTGGCACTCCG AGGTTACGCGTTCAGCGAAGATGGTGAATATTTTGCCTATGGTCTGAGTGCCAGTGGCTC AGACTGGGTGACAATCAAGTTCATGAAAGTTGATGGTGCCAAAGAGCTTCCAGATGTGCT TGAAAGAGTCAAGTTCAGCTGTATGGCCTGGACCCATGATGGGAAGGGAATGTTCTACAA CTCATACCCTCAACAGGATGGAAAAAGTGATGGCACAGAGACATCTACCAATCTCCACCA AAAGCTCTACTACCATGTCTTGGGAACCGATCAGTCAGAAGATATTTTGTGTGCTGAGTT TCCTGATGAACCTAAATGGATGGGTGGAGCTGAGTTATCTGATGATGGCCGCTATGTCTT GTTATCAATAAGGGAAGGATGTGATCCAGTAAACCGACTCTGGTACTGTGACCTACAGCA GGAATCCAGTGGCATCGCGGGAATCCTGAAGTGGGTAAAACTGATTGACAACTTTGAAGG GGAATATGACTACGTGACCAATGAGGGGACGGTGTTCACATTCAAGACGAATCGCCAGTC TCCCAACTATCGCGTGATCAACATTGACTTCAGGGATCCTGAAGAGTCTAAGTGGAAAGT ACTTGTTCCTGAGCATGAGAAAGATGTCTTAGAATGGATAGCTTGTGTCAGGTCCAACTT CTTGGTCTTATGCTACCTCCATGACGTCAAGAACATTCTGCAGCTCCATGACCTGACTAC TGGTGCTCTCCTTAAGACCTTTCCGCTCGATGTCGGCAGCATTGTAGGGTACAGCGGTCA GAAGAAGGACACTGAAATCTTCTATCAGTTTACTTCCTTTTTATCTCCAGGTATCATTTA TCACTGTGATCTTACCAAAGAGGAGCTGGAGCCAAGAGTTTTCCGAGAGGTGACCGTAAA AGGAATTGATGCTTCTGATTACCAGACAGTCCAGATTTTCTACCCTAGCAAGGATGGTAC GAAGATTCCAATGTTCATTGTGCATAAAAAAGGCATAAAATTGGATGGCTCTCATCCAGC TTTCTTATATGGCTATGGCGGCTTCAACATATCCATCACACCCAACTACAGTGTTTCCAG GCTTATTTTTGTGAGACACATGGGTGGTATCCTGGCAGTGGCCAACATCAGAGGAGGTGG CGAATATGGAGAGACGTGGCATAAAGGTGGTATCTTGGCCAACAAACAAAACTGCTTTGA TGACTTTCAGTGTGCTGCTGAGTATCTGATCAAGGAAGGTTACACATCTCCCAAGAGGCT GACTATTAATGGAGGTTCAAATGGAGGCCTCTTAGTGGCTGCTTGTGCAAATCAGAGACC TGACCTCTTTGGTTGTGTTATTGCCCAAGTTGGAGTAATGGACATGCTGAAGTTTCATAA ATATACCATCGGCCATGCTTGGACCACTGATTATGGGTGCTCGGACAGCAAACAACACTT TGAATGGCTTGTCAAATACTCTCCATTGCATAATGTGAAGTTACCAGAAGCAGATGACAT CCAGTACCCGTCCATGCTGCTCCTCACTGCTGACCATGATGACCGCGTGGTCCCGCTTCA CTCCCTGAAGTTCATTGCCACCCTTCAGTACATCGTGGGCCGCAGCAGGAAGCAAAGCAA CCCCCTGCTTATCCACGTGGACACCAAGGCGGGCCACGGGGCGGGGAAGCCCACAGCCAA AGTGATAGAGGAAGTCTCAGACATGTTTGCGTTCATCGCGCGGTGCCTGAACGTCGACTG GATTCCATAAACAGTTTTCGTGCTTCCTCCTGACAGCGACAGAAAACCTCAAGGGCTTTC CCACGTTGACACCAAGAAACCACTGGGCATAATGCTTCCCCACGGGAACATTATTCCTGC ACTCACAGGCTACAGTTGAACAGAACTGCCGTGGGAATTTTATCTTTTTTAGGCTTCTCC TTTTTAGCAAGGCCTTGGTGTTTCTTTTTCCACCCTGTCTAGGCACATGTGGTTTTTTGG TGTTTTTTTTAAGGGCATGTTGGGATAAATAGCTAAATGGCAACAAACACATTGTGAATA TTAGATTGCTGAATTAAGGATCATAGTCGGGCATACTTATCTATATCCATAACCTCTATA TCTTTAAATAAATGTGAGAACTGTTCTCATGGAGAAGACTTCTTTGCAACAATAATAAAT GTTATTTAAGAATGAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_002726 unedited
GCACAATTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCTGGCCGTGAGC CGGCCGCCCGCTGCCGCCGGCCGCCCCGCAGCTGCCTGCGCCCCAGCCGCGCCTCGCGGC CAGCCCGGCTAGCTCAGGTCCGCTCCCGGAGCCCGCGCCCCTCCACGCTGCCCCCTGCCT GTCCCCGGCCATGCTGTCCCTTCAGTACCCCGACGTGTACCGCGACGAGACCGCCGTACA GGATTATCATGGTCATAAAATTTGTGACCCTTACGCCTGGCTTGAAGACCCCGACAGTGA ACAGACTAAGGCCTTTGTGGAGGCCCAGAATAAGATTACTGTGCCATTTCTTGAGCAGTG TCCCATCAGAGGTTTATACAAAGAGAGAATGACTGAACTATATGATTATCCCAAGTATAG TTGCCACTTCAAGAAAGGAAAACGGTATTTTTATTTTTACAATACAGGTTTGCAGAACCA GCGAGTATTATATGTACAGGATTCCTTAGAGGGTGAGGCCAGAGTGTTCCTGGACCCCAA CATACTGTCTGACGATGGCACAGTGGCACTCCGAGGTTACGCGTTCAGCGAAGATGGTGA ATATTTTGCCTATGGTCTGAGTGCCAGTGGCTCAGACTGGGTGACAATCAAGTTCATGAA AGTTGATGGTGCCAAAGAGCTTCCAGATGTGCTTGAAAGAGTCAAGTTCAGCTGTATGGC CTGTACCCATGATGGGAANGGAATGTTCTACAACTCATACCCTCCACAGGATGGGAAAAG TGATGGCACAGAGACATCTACCAATCTCCACCAAAAGCTCTACTACCATGTCTTGGGGAC CGATCAGTCAGAAGATATTTTGTGTGCTGAGNTTTCTGATGAACCCTAATGGATGGTGGA GCTNGAGTATCTGATGATGGCCGCTATGTTCTGTTATCATTAAGAAG >OriGene 3' read for NM_002726 unedited
GGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAATTCCTTAAATAACATTTAT TATTGTTGCAAAGAAGTCTTCTCCATGAGAACAGTTCTCACATTTATTTAAAGATATAGA GGTTATGGATATAGATAAGTATGCCCGACTATGATCCTTAATTCAGCAATCTAATATTCA CAATGTGTTTGTTGCCATTTAGCTATTTATCCCAACATGCCCTTAAAAAAAACACCAAAA AACCACATGTGCCTAGACAGGGTGGAAAAAGAAACACCAAGGCCTTGCTAAAAAGGAGAA GCCTAAAAAAGATAAAATTCCCACGGCAGTTCTGTTCAACTGTAGCCTGTGAGTGCAGGA ATAATGTTCCCGTGGGGAAGCATTATGCCCAGTGGTTTCTTGGTGTCAACGTGGGAAAGC CCTTGAGGTTTTCTGTCGCTGTCAGGAGGAAGCACGAAAACTGTTTATGGAATCCAGTCG ACGTTCAGGCACCGCGCGATGAACGCAAACATGTCTGAGACTTCCTCTATCACTTTGGCT GTGGGCTTCCCCGCCCCGTGGCCCGCCTTGGTGTCCACGTGGATAAGCAGGGGGTTGCTT TGCTTCCTGCTGCGGCCCACGATGTACTGAAGGGTGGCAATGAACTTCAGGGAGTGAAGC GGGACCACGCGGTCATCATGGTCAGCAGTGAGGAGCAGCATGGACGGGTACTGGATGTCA TCTGCTTCTGGTAACTTCACATATGCAATGGAGAGTATTTGACAAGCCATTCAAAGTGTT GTTTGCTGTCCGAGCACCATAATCAGTGGTCCAGCATGGCCGATGGTATATTATGAAACT CAGCATGTCCATACNNTCACTGGGCATTACACACCAAGNAGTCAGGTCTCTGATTGCACA GCAGCACTAAGAGCCCTCATTGAACCTCATATAGTCAGCTTTGGGAGAGGGAACCTNCTG ATAGACTCANAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002726 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002726.3, NP_002717.3 |
| RefSeq Size | 2849 bp |
| RefSeq ORF | 2133 bp |
| Locus ID | 5550 |
| UniProt ID | P48147 |
| Domains | Peptidase_S9, Peptidase_S9_N |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse
,Savolainen, MH;Richie, CT;Harvey, BK;Männistö, PT;Maguire-Zeiss, KA;Myöhänen, TT;,
Neurobiol. Dis . April 2014
,PubMed ID 24746855
[PREP]
|
|
Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity
,Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf,
J. Biol. Chem. 2006 Mar 17;281(11):7437-44.
[PREP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203596 | PREP (Myc-DDK-tagged)-Human prolyl endopeptidase (PREP) |
CNY 5,200.00 |
|
| RC203596L1 | Lenti ORF clone of Human prolyl endopeptidase (PREP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203596L2 | Lenti ORF clone of Human prolyl endopeptidase (PREP), mGFP tagged |
CNY 5,890.00 |
|
| RC203596L3 | Lenti ORF clone of Human prolyl endopeptidase (PREP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203596L4 | Lenti ORF clone of Human prolyl endopeptidase (PREP), mGFP tagged |
CNY 5,890.00 |
|
| RG203596 | PREP (tGFP-tagged) - Human prolyl endopeptidase (PREP) |
CNY 6,800.00 |
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