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PFKP (NM_002627) Human Untagged Clone
CAT＃: SC118507
PFKP (untagged)-Human phosphofructokinase, platelet (PFKP), transcript variant 1
CNY 5,752.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATP-PFK; PFK-C; PFK-P; PFKF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118507 sequence for NM_002627 edited (data generated by NextGen Sequencing)
ATGGACGCGGACGACTCCCGGGCCCCCAAGGGCTCCTTGCGGAAGTTCCTGGAGCACCTC TCCGGGGCCGGCAAGGCCATCGGCGTGCTGACCAGCGGCGGGGATGCTCAAGGTATGAAC GCTGCCGTCCGTGCCGTGGTGCGCATGGGTATCTACGTGGGGGCCAAGGTGTACTTCATC TACGAGGGCTACCAGGGCATGGTGGACGGAGGCTCAAACATCGCAGAGGCCGACTGGGAG AGTGTCTCCAGCATCCTGCAAGTGGGCGGGACGATCATTGGCAGTGCGCGGTGCCAGGCC TTCCGCACGCGGGAAGGCCGCCTGAAGGCTGCTTGCAACCTGCTGCAGCGCGGCATCACC AACCTGTGTGTGATCGGCGGGGACGGGAGCCTCACCGGGGCCAACCTCTTCCGGAAGGAG TGGAGTGGGCTGCTGGAGGAGCTGGCCAGGAACGGCCAGATCGATAAGGAGGCCGTGCAG AAGTACGCCTACCTCAACGTGGTGGGCATGGTGGGCTCCATCGACAATGATTTCTGCGGC ACCGACATGACCATCGGCACGGACTCCGCCCTGCACAGGATCATCGAGGTCGTCGACGCC ATCATGACCACGGCCCAGAGCCACCAGAGGACCTTCGTTCTGGAGGTGATGGGACGACAC TGTGGGTACCTGGCCCTGGTGAGTGCCTTGGCCTGCGGTGCGGACTGGGTGTTCCTTCCA GAATCTCCACCAGAGGAAGGCTGGGAGGAGCAGATGTGTGTCAAACTCTCGGAGAACCGT GCCCGGAAAAAAAGGCTGAATATTATTATTGTGGCTGAAGGAGCAATTGATACCCAAAAT AAACCCATCACCTCTGAGAAAATCAAAGAGCTTGTCGTCACGCAGCTGGGCTATGACACA CGTGTGACCATCCTCGGGCACGTGCAGAGAGGAGGGACCCCTTCGGCATTTGACAGGATC TTGGCCAGCCGCATGGGAGTGGAGGCAGTCATCGCCTTGCTAGAGGCCACCCCGGACACC CCAGCTTGCGTCGTGTCACTGAACGGGAACCACGCCGTGCGCCTGCCGCTGATGGAGTGC GTGCAGATGACTCAGGATGTGCAGAAGGCGATGGACGAGAGGAGATTTCAAGATGCGGTT CGACTCCGAGGGAGGAGCTTTGCGGGCAACCTGAACACCTACAAGCGACTTGCCATCAAG CTGCCGGATGATCAGATCCCAAAGACCAATTGCAACGTAGCTGTCATCAACGTGGGGGCA CCCGCGGCTGGGATGAACGCGGCCGTACGCTCAGCTGTGCGCGTGGGCATTGCCGACGGC CACAGGATGCTCGCCATCTATGATGGCTTTGACGGCTTCGCCAAGGGCCAGATCAAAGAA ATCGGCTGGACAGATGTCGGGGGCTGGACCGGCCAAGGAGGCTCCATTCTTGGGACAAAA CGCGTTCTCCCGGGGAAGTACTTGGAAGAGATCGCCACACAGATGCGCACGCACAGCATC AACGCGCTGCTGATCATCGGTGGATTCGAGGCCTACCTGGGACTCCTGGAGCTGTCAGCC GCCCGGGAGAAGCACGAGGAGTTCTGTGTCCCCATGGTCATGGTTCCCGCTACTGTGTCC AACAATGTGCCGGGTTCCGATTTCAGCATCGGGGCAGACACCGCCCTGAACACTATCACC GACACCTGCGACCGCATCAAGCAGTCCGCCAGCGGAACCAAGCGGCGCGTGTTCATCATC GAGACCATGGGCGGCTACTGTGGCTACCTGGCCAACATGGGGGGGCTCGCGGCTGGAGCT GATGCCGCATACATTTTCGAAGAGCCCTTCGACATCAGGGATCTGCAGTCCAACGTGGAG CACCTGACGGAGAAAATGAAGACCACCATCCAGAGAGGCCTTGTGCTCAGAAATGAGAGC TGCAGTGAAAACTACACCACCGACTTCATTTACCAGCTGTATTCAGAAGAGGGCAAAGGC GTGTTTGACTGCAGGAAGAACGTGCTGGGTCACATGCAGCAGGGTGGGGCACCCTCTCCA TTTGATAGAAACTTTGGAACCAAAATCTCTGCCAGAGCTATGGAGTGGATCACTGCAAAA CTCAAGGAGGCCCGGGGCAGAGGAAAAAAATTTACCACCGATGATTCCATTTGTGTGCTG GGAATAAGCAAAAGAAACGTTATTTTTCAACCTGTGGCAGAGCTGAAGAAGCAAACGGAT TTTGAGCACAGGATTCCCAAAGAACAGTGGTGGCTCAAGCTACGGCCCCTCATGAAAATC CTGGCCAAGTACAAGGCCAGCTATGACGTGTCGGACTCAGGCCAGCTGGAACATGTGCAG CCCTGGAGTGTCTGA Clone variation with respect to NM_002627.4 951 c=>t;1281 a=>g;1794 c=>t >OriGene 5' read for NM_002627 unedited
GTCAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCCCATTGCC TGCTGCGCACCCGGACGTGCGGCTCCCCTCGGCCTCCTCGCCATGGACGCGGACGACTCC CGGGCCCCCAGGGCTCCTTGCGGAAGTTCCTGGAGCACCTCTCCGGGGCCGGCAAGGCCA TCGGCGTGCTGACCAGCGGCGGGGATGCTCAAGGTATGAACGCTGCCGTCCGTGCCGTGG TGCGCATGGGTATCTACGTGGGGGCCAAGGTGTACTTCATCTACGAGGGCTACCAGGGCA TGGTGGACGGAGGCTCAAACATCGCAGAGGCCGACTGGGAGAGTGTCTCCAGCATCCTGC AAGTGGGCGGGACGATCATTGGCAGTGCGCGGTGCCAGGCCTTCCGCACGCGGGAAGGCC GCCTGAAGGCTGCTTGCAACCTGCTGCAGCGCGGCATCACCAACCTGTGTGTGATCGGCG GGGACGGGAGCCTCACCGGGGCCAACCTCTTCCGGAAGGAGTGGAGTGGGCTGCTGGAGG AGCTGGCCAGGAACGGCCAGATCGATAAGGAGGCCGTGCAGAAGTACGCCTACCTCAACG TGGTGGGCATGGTGGGCTCCATCGACAATGATTTCTGCGGCACCGACATGACCATCGGCA CGGACTCCGCCCTGCACAGGATCATCGAGGTCGTCGACGCCATCATGACCACGGCCCAGA GCCACCAGAGGACCTTCGTTCTGGNAGGTGATGGGACGACACTGTGGGTACCTGGCCCTG GTGAGTGCCTTGGCCTGCGGTGCGACTCTGGTTGTTCCTTNNCAGAATCTCCACCANAGA ANGNCTGGGAGGAGCANNATGTGTGTCAAACTCTCGGAGAACCGTGCCCGGAAAAAAGGC TGATTTTATATTGGG >OriGene 3' read for NM_002627 unedited
CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGAGTTGTAGGCAAATGTTTA ATTCTGCTCATATGCACATCTGAAAGCATGAGACACACTCCACAGACAGCACGCACTGGG GCTGGTGGGGCAGATGGGCACTCGCCGATTAGGTATTAATGTTAATAATACGTGCATAAA GTGCTGATAAAATAACTTAAGTGTTACAAAAACAGACAGTCCACGGTGGCTGCAGGCACA TGCAGGCGGGACTGGGTCAGACACTCCAGGGCTGCACATGTTCCAGCTGGCCTGAGTCCG ACACGTCATAGCTGGCCTTGTACTTGGCCAGGATTTTCATGAGGGGCCGTAGCTTGAGCC ACCACTGTTCTTTGGGAATCCTGTGCTCAAAATCCGTTTGCTTCTTCAGCTCTGCCACAG GTTGAAAAATAACGTTTCTTTTGCTTATTCCCAGCACACAAATGGAATCATCGGTGGTAA ATTTTTTTCCTCTGCCCCGGGCCTCCTTGAGTTTTGCAGTGATCCACTCCATAGCTCTGG CAGAGATTTTGGTTCCAAAGTTTCTATCAAATGGAGAGGGTGCCCCACCCTGCTGCATGT GACCCAGCACGTTCTTCCTGCAGTCAAACACGCCTTTGCCCTCTTCTGAATACAGCTGGT AAATGAAGTCGGTGGTGTAGTTTTCACTGCAGCTCTCATTTCTGAGCACAAGGCCTCTCT GGATGGTGGTCTTCATTCTCTCCGTCACGTGCTCCACGTTTGACTGCACATCCCTGATGT CNAAAGGCTCTTCCAAATGTATGCGGCATCAGCTCCAGCCGCGAGCCCCCCCATTTTGGC CAAGTACCCCAGTTACCGCCCATGTTCTTNATGATGACACCCCCGCTTGGTTCCCTTGCC GACTGTTTGATCCGTCCAGGTGTCGGAAATTGTTAGGCCGTGTTTGCCCGATGTGAAATC GAACCGGCAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002627 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002627.3, NP_002618.1 |
| RefSeq Size | 2628 bp |
| RefSeq ORF | 2355 bp |
| Locus ID | 5214 |
| UniProt ID | Q01813 |
| Domains | PFK |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway |
| Gene Summary | This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects
,Cowan, JR;Tariq, M;Shaw, C;Rao, M;Belmont, JW;Lalani, SR;Smolarek, TA;Ware, SM;,
Philos. Trans. R. Soc. Lond., B, Biol. Sci.
,PubMed ID 27821535
[PFKP]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200673 | PFKP (Myc-DDK-tagged)-Human phosphofructokinase, platelet (PFKP), transcript variant 1 |
CNY 5,744.00 |
|
| RC200673L1 | Lenti ORF clone of Human phosphofructokinase, platelet (PFKP), transcript variant 1, Myc-DDK-tagged |
CNY 8,144.00 |
|
| RC200673L2 | Lenti ORF clone of Human phosphofructokinase, platelet (PFKP), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RC200673L3 | Lenti ORF clone of Human phosphofructokinase, platelet (PFKP), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC200673L4 | Lenti ORF clone of Human phosphofructokinase, platelet (PFKP), transcript variant 1, mGFP tagged |
CNY 8,144.00 |
|
| RG200673 | PFKP (tGFP-tagged) - Human phosphofructokinase, platelet (PFKP), transcript variant 1 |
CNY 7,344.00 |
