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NMBR (NM_002511) Human Untagged Clone
CAT＃: SC118568
NMBR (untagged)-Human neuromedin B receptor (NMBR)
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BB1; BB1R; BRS1; NMB-R |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002511 edited
GGCTTGCCCCGCGGACAGTAAACTTGCAGGGGCGAGAGGGAGGGACATCGATTAAACCTA AATCGTGGGCGTTCAGTCCTCAGGGCACCGGAGCGCGTGAAAACTCCAGCGGACTCTGCT GGAAAGGAGATCATGCCCTCTAAGTCTCTTTCCAACCTCTCGGTGACCACCGGCGCGAAT GAGAGCGGTTCCGTTCCCGAGGGGTGGGAAAGGGATTTCCTGCCGGCCTCGGACGGGACC ACCACGGAGTTGGTGATCCGCTGTGTGATCCCGTCCCTCTACCTGCTCATCATCACCGTG GGCTTGCTGGGCAACATCATGCTGGTGAAGATCTTCATCACCAACAGCGCCATGAGGAGC GTCCCCAACATCTTCATCTCTAACCTGGCGGCCGGGGACTTGCTGCTGCTGCTCACCTGC GTCCCGGTGGACGCCTCGCGCTACTTCTTCGACGAGTGGATGTTTGGCAAGGTGGGCTGC AAACTGATCCCTGTCATCCAGCTCACTTCCGTGGGGGTTTCCGTGTTCACTCTCACTGCC CTCAGCGCCGACAGGTACAGAGCCATCGTTAACCCCATGGACATGCAGACGTCAGGGGCA TTGCTGCGGACCTGTGTGAAGGCCATGGGTATCTGGGTGGTCTCCGTGTTGCTGGCAGTT CCCGAAGCGGTGTTTTCAGAAGTGGCTCGCATCAGTAGCTTGGATAATAGCAGCTTCACA GCATGTATCCCATACCCTCAAACAGATGAATTACATCCAAAGATTCATTCAGTGCTCATT TTCTTGGTCTATTTCCTCATACCACTTGCTATTATTAGCATTTATTATTATCATATTGCA AAGACCTTAATTAAAAGCGCACACAATCTTCCTGGAGAATACAATGAACATACCAAAAAA CAGATGGAAACACGGAAACGCCTGGCTAAAATTGTGCTTGTCTTTGTGGGCTGTTTCATC TTCTGTTGGTTTCCAAACCACATCCTTTACATGTATCGGTCTTTCAACTATAATGAGATT GATCCATCTCTAGGCCACATGATTGTCACCTTAGTTGCCCGGGTTCTCAGTTTTGGCAAT TCTTGTGTCAACCCATTTGCTCTTTACCTACTCAGTGAAAGCTTCAGGAGGCATTTCAAT AGCCAACTCTGCTGTGGGAGGAAGTCCTATCAAGAGAGAGGAACCAGCTACCTACTCAGC TCTTCAGCGGTGCGTATGACATCTCTGAAAAGCAATGCTAAGAACATGGTGACCAATTCT GTTTTACTAAATGGGCACAGCATGAAGCAGGAAATGGCACTGTGATTTTGGCCATTCAAC TCACTACCTGGAGAGAACTTAGTAACTGTTAAAATTCCTATTCGGCAGATCAGAACTTGC TGTTGCTTAGCTAATTTATTAGGCAATTGCATGATTGACTCAGAAAATGCAAGACATTTT TTCTCTACACTAGACTTTATTTTTTCTCTTTTCATTTCCTAATAATTAGAATATGAGAAA AGACTTTAAATCACTACATATAATACATATATGTATATATATGTATTTGCACACACACAT GTACACACATGTACATTATATATATTTCACATTTAAGATGATCCCCAAACCAATGCAATA TGTATAATTTAACATTGCTTTAGTATTTAGGCTGTTGCTAAAGCCAGTTCTAGCATATTT GTCTTAGGTTTTGTTTTATCTTGAAGCATGAAATAAATTTCTATATTGACTCAATGATTC AGTGAGGGTAATATTCAAACTCCTATTATTTGAAATACAAGTCAGATTGTCCTGGTGAAT TTCATTCAATTCACAACTATTGCATGAGTGTGTGTGTGTGTGTGTATATATATATGTATA TGTATATATGTACACACACACACGTCCTTCATTTTAAGAAAATAAGAAAAAATTCAAAGG TGGAGCTTAATCAAATTGGTATTTATTGTGATTCTGTGATTAATCATAATTTATAGAAAT AATTCATATCTGTAATTCTAAGTATGTGATTAACAGATATAATGAAATTAATATTATGAA TTATAAAATAGATATGATATGAATATAATTTATATTATGAATGTAAAATAGGTATCATAT GAATATGATTTACATTATGAATGTAAAATAGGTATCATATGTCCCAAATTGCAAAGCTAC AACTCACAAGTTTGCATGGCCATCTTAGTATACATTGCTAAATCCTGGAATATTTGGATG ATTGTGTATAGATGTGATAAGATTTGTGTAATTCCAGTGAGTTCAACCATTTACTCATCC TCTCTTGCAATACCCAACTGACAAGTATGTGGGATCACACTTAGGCAATTTTTTTCTGCT TTTCCTGCATGATACCACAGTTTTCTCTGAATAAATGTCTTCTTTTTTTAGGAAAATGCA AATGTATTGATTACAGTTTAAAAGCTACCTTTTTAAAAGCATGTATCAATAATCTAAACA TTTAAATCAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_002511 unedited
CCCCACCCAATTTGNGGATTTNTGTNAACACGAACTTCATTTGNAGGGCTGGCCGCGCAA TTCGGCACCAGGGACTTGCTCCCGCGGAACAGTAAACTTGCAGGGGCGAGAGGGAGGGAC ATCGATTAAACCTAAATCGTGGGCGTTCAGTCCTCAGGGCACCGGAGCGCGTGAAAACTC CAGCGGACTCTGCTGGAAAGGAGATCATGCCCTCTAAGTCTCTTTCCAACCTCTCGGTGA CCACCGGCGCGAATGAGAGCGGTTCCGTTCCCGAGGGGTGGGAAAGGGATTTCCTGCCGG CCTCGGACGGGACCACCACGGAGTTGGTGATCCGCTGTGTGATCCCGTCCCTCTACCTGC TCATCATCACCGTGGGCTTGCTGGGCAACATCATGCTGGTGAAGATCTTCATCACCAACA GCGCCATGAGGAGCGTCCTCTACATCTTCATCTCTCACCTGNCGGCCCGGNGACTTGCTG CTGCTGCTCACCTGCGTCCCGGTGGACGCCTTGCGCTACTTCATCGACGAGTGGATGTTT GGCACGGTGGGCTGCAAACTGATCCCTGTCATCCAGCTCACTTCCGTGGGGGATATCGGG TTCACTTTAACTGCCCTAAGCGCCGACGGTACCAGACCATCGTTAACCCCTGGACATTCC AACGTCCGGGGCATTGTTTGGGACTTTTGTAAAGGCAGGGGTAACTGGGGGGGCCTCCGG GTTGCTGGGCAATCCCCAAACGGGGTTTTCAAAAGGGCCTTCCAATAAAAACTTTGGAAA AAAACCACTTTCCCCGCATGGGATCCTTCCCTTTTAAACGGAGGAAATAACCCCCAAAAA ATTTTTCCGGGGCATATTTTTTGGGGATAATTTCTTCACACACCTGGTTATATAAAACAC ATATATT >OriGene 3' read for NM_002511 unedited
GGGGCATCCTGTGANACCACGGCTCGATTTTNAGGANCGNGNTTTTTTTTTTTTTTTTTT TGATTTAAATGTTTAGATTATTGATACATGCTTTTAAAAAGGTAGCTTTTAAACTGTAAT CAATACATTTGCATTTTCCTAAAAAAAGAAGACATTTATTCAGAGAAAACTGTGGTATCA TGCAGGAAAAGCAGAAAAAAATTGCCTAAGTGTGATCCCACATACTTGTCAGTTGGGTAT TGCAAGAGAGGATGAGTAAATGGTTGAACTCACTGGAATTACACAAATCTTATCACATCT ATACACAATCATCCAAATATTCCAGGATTTAGCAATGTATACTAAGATGGCCATGCAAAC TTGTGAGTTGTAGCTTTGCAATTTGGGACATATGATACCTATTTTACATTCATAATGTAA ATCATATTCATATGATACCTATTTTACATTCATAATATAAATTATATTCATATCATATCT ATTTTATAATTCATAATATTAATTTCATTATATCTGTTAATCACATACTTAGAATTACAG ATATGAATTATTTCTATAAATTATGATTAATCACAGAATCACAATAAATACCAATTTGAT TAAGCTCCACCTTTGAATTTTTTCTTATTTTCTTAAAATGAAGGACGTGTGTGTGTGTAC ATATATACATATACATATATATATACACACACACACACACACTCATGCAATAGTTGTGAA TTGAATGAAATTCCCCAGGACAATCTGACTTGTATTTCAAATAATAGGAGTTTGAATATT ACCCTCACTGAATCATTGAGTCAATATAGAACATTATTTCATGCTTTCAGAAAAACAAAC CTAAGACAATATGCTACAACTGGCTTTACCACAGCCTAAATCTAAAGCATGTTAACTATA CTATTGCATGGCTTGGGAACCACCTCACGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002511 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002511.1, NP_002502.1 |
| RefSeq Size | 1352 bp |
| RefSeq ORF | 1173 bp |
| Locus ID | 4829 |
| UniProt ID | P28336 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213319 | NMBR (Myc-DDK-tagged)-Human neuromedin B receptor (NMBR) |
CNY 5,488.00 |
|
| RC213319L1 | Lenti ORF clone of Human neuromedin B receptor (NMBR), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC213319L2 | Lenti ORF clone of Human neuromedin B receptor (NMBR), mGFP tagged |
CNY 5,890.00 |
|
| RC213319L3 | Lenti ORF clone of Human neuromedin B receptor (NMBR), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC213319L4 | Lenti ORF clone of Human neuromedin B receptor (NMBR), mGFP tagged |
CNY 7,888.00 |
|
| RG213319 | NMBR (tGFP-tagged) - Human neuromedin B receptor (NMBR) |
CNY 7,088.00 |
