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NFkB p100 / p52 (NFKB2) (NM_002502) Human Untagged Clone
CAT＃: SC118626
NFKB2 (untagged)-Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2
CNY 6,840.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p49/p100; p52; p100 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118626 sequence for NM_002502 edited (data generated by NextGen Sequencing)
ATGGAGAGTTGCTACAACCCAGGTCTGGATGGTATTATTGAATATGATGATTTCAAATTG AACTCCTCCATTGTGGAACCCAAGGAGCCAGCCCCAGAAACAGCTGATGGCCCCTACCTG GTGATCGTGGAACAGCCTAAGCAGAGAGGCTTTCGATTTCGATATGGCTGTGAAGGCCCC TCCCATGGAGGACTGCCCGGTGCCTCCAGTGAGAAGGGCCGAAAGACCTATCCCACTGTC AAGATCTGTAACTACGAGGGACCAGCCAAGATCGAGGTGGACCTGGTAACACACAGTGAC CCACCTCGTGCTCATGCCCACAGTCTGGTGGGCAAGCAATGCTCGGAGCTGGGGATCTGC GCCGTTTCTGTGGGGCCCAAGGACATGACTGCCCAATTTAACAACCTGGGTGTCCTGCAT GTGACTAAGAAGAACATGATGGGGACTATGATACAAAAACTTCAGAGGCAGCGGCTCCGC TCTAGGCCCCAGGGCCTTACGGAGGCCGAGCAGCGGGAGCTGGAGCAAGAGGCCAAAGAA CTGAAGAAGGTGATGGATCTGAGTATAGTGCGGCTGCGCTTCTCTGCCTTCCTTAGAGCC AGTGATGGCTCCTTCTCCCTGCCCCTGAAGCCAGTCATCTCCCAGCCCATCCATGACAGC AAATCTCCGGGGGCATCAAACCTGAAGATTTCTCGAATGGACAAGACAGCAGGCTCTGTG CGGGGTGGAGATGAAGTTTATCTGCTTTGTGACAAGGTGCAGAAAGATGACATTGAGGTT CGGTTCTATGAGGATGATGAGAATGGATGGCAGGCCTTTGGGGACTTCTCTCCCACAGAT GTGCATAAACAGTATGCCATTGTGTTCCGGACACCCCCCTATCACAAGATGAAGATTGAG CGGCCTGTAACAGTGTTTCTGCAACTGAAACGCAAGCGAGGAGGGGACGTGTCTGATTCC AAACAGTTCACCTATTACCCTCTGGTGGAAGACAAGGAAGAGGTGCAGCGGAAGCGGAGG AAGGCCTTGCCCACCTTCTCCCAGCCCTTCGGGGGTGGCTCCCACATGGGTGGAGGCTCT GGGGGTGCAGCCGGGGGCTACGGAGGAGCTGGAGGAGGTGGCAGCCTCGGTTTCTTCCCC TCCTCCCTGGCCTACAGCCCCTACCAGTCCGGCGCGGGCCCCATGGGCTGCTACCCGGGA GGCGGGGGCGGGGCGCAGATGGCCGCCACGGTGCCCAGCAGGGACTCCGGGGAGGAAGCC GCGGAGCCGAGCGCCCCCTCCAGGACCCCCCAGTGCGAGCCGCAGGCCCCGGAGATGCTG CAGCGAGCTCGAGAGTACAACGCGCGCCTGTTCGGCCTGGCGCAGCGCAGCGCCCGAGCC CTACTCGACTACGGCGTCACCGCGGACGCGCGCGCGCTGCTGGCGGGACAGCGCCACCTG CTGACGGCGCAGGACGAGAACGGAGACACACCACTGCACCTAGCCATCATCCACGGGCAG ACCAGTGTCATTGAGCAGATAGTCTATGTCATCCACCACGCCCAGGACCTCGGCGTTGTC AACCTCACCAACCACCTGCACCAGACGCCCCTGCACCTGGCGGTGATCACGGGGCAGACG AGTGTGGTGAGCTTTCTGCTGCGGGTAGGTGCAGACCCAGCTCTGCTGGATCGGCATGGA GACTCAGCCATGCATCTGGCGCTGCGGGCAGGCGCTGGTGCTCCTGAGCTGCTGCGTGCA CTGCTTCAGAGTGGAGCTCCTGCTGTGCCCCAGCTGTTGCATATGCCTGACTTTGAGGGA CTGTATCCAGTACACCTGGCGGTCCGAGCCCGAAGCCCTGAGTGCCTGGATCTGCTGGTG GACAGTGGGGCTGAAGTGGAGGCCACAGAGCGGCAGGGGGGACGAACAGCCTTGCATCTA GCCACAGAGATGGAGGAGCTGGGGTTGGTCACCCATCTGGTCACCAAGCTCCGGGCCAAC GTGAACGCTCGCACCTTTGCGGGAAACACACCCCTGCACCTGGCAGCTGGACTGGGGTAC CCGACCCTCACCCGCCTCCTTCTGAAGGCTGGTGCTGACATCCATGCTGAAAACGAGGAG CCCCTGTGCCCACTGCCTTCACCCCCTACCTCTGATAGCGACTCGGACTCTGAAGGGCCT GAGAAGGACACCCGAAGCAGCTTCCGGGGCCACACGCCTCTTGACCTCACTTGCAGCACC AAGGTGAAGACCTTGCTGCTAAATGCTGCTCAGAACACCATGGAGCCACCCCTGACCCCG CCCAGCCCAGCAGGGCCGGGACTGTCACTTGGTGATACAGCTCTGCAGAACCTGGAGCAG CTGCTAGACGGGCCAGAAGCCCAGGGCAGCTGGGCAGAGCTGGCAGAGCGTCTGGGGCTG CGCAGCCTGGTAGACACGTACCGACAGACAACCTCACCCAGTGGCAGCCTCCTGCGCAGC TACGAGCTGGCTGGCGGGGACCTGGCAGGTCTACTGGAGGCCCTGTCTGACATGGGCCTA GAGGAGGGAGTGAGGCTGCTGAGGGGTCCAGAAACCCGAGACAAGCTGCCCAGCACAGAG GTGAAGGAAGACAGTGCGTACGGGAGCCAGTCAGTGGAGCAGGAGGCAGAGAAGCTGGGC CCACCCCCTGAGCCACCAGGAGGGCTCTGCCACGGGCACCCCCAGCCTCAGGTGCACTGA Clone variation with respect to NM_002502.3 153 c=>t >OriGene 5' read for NM_002502 unedited
NGGTCANCATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCTCCACCG GATCTCACCCGCCACACCCGGCCAGGCGGCTGGAGGAGGCGGGCGTCTAAAATTCTGGGA AGCAGAACCTGGCCGGAGCCACTAGACAGAGCCGGGCCTAGCCCAGAGACATGGAGAGTT GCTACAACCCAGGTCTGGATGGTATTATTGAATATGATGATTTCAAATTGAACTCCTCCA TTGTGGAACCCAAGGAGCCAGCCCCAGAAACAGCTGATGGCCCCTACCTGGTGATCGTGG AACAGCCTAAGCAGAGAGGCTTTCGATTTCGATATGGCTGTGAAGGCCCCTCCCATGGAG GACTGCCCGGTGCCTCCAGTGAGAAGGGCCGAAAGACCTATCCCACTGTCAAGATCTGTA ACTACGAGGGACCAGCCAAGATCGAGGTGGACCTGGTAACACACAGTGACCCACCTCGTG CTCATGCCCACAGTCTGGTGGGCAAGCAATGCTCGGAGCTGGGGATCTGCGCCGTTTCTG TGGGGCCCAAGGACATGACTGCCCAATTTAACAACCTGGGTGTCCTGCATGTGACTAAGA AGAACATGATGGGGACTATGATACAAAAACTTCAGAGGCAGCGGCTCCGCTCTAGGCCCC AGGGCCTTACGGAGGCCGAGCAGCGGGAGCTGGAGCAAGAGCCAAAGAACTGAAGAAGGT GATGGATCTGAGTATAGTGCGGCTGCGCTTCTCTGCCTTCCTTAGAGCCAGNGATGGCTC CTNTCTCCTGCCCCTGAAGCCAGTCATCTTCCAGCCCATCCATGACAGCAAATCTCCGGG GGCATCAAACCTGNAAGATTCTCGAATGGACAAGACAGCAGGCTCTGTGCGGGGTGGAGT >OriGene 3' read for NM_002502 unedited
GACCGCGGCCCGCTTCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTAAGGGGGGAAGGAGGGGTCCTCCCCTTCCCATGAAAATCCTTTAT TTGTCCCAACTGAGGGGTGGGTGTGGGGTGTTAAATAAAATTTGAAATAGGGGGGGACCC TGTACAGGGGGTCCGGGAAGGGGGCTGGGGGCAGGCAACAGGTCAGTGCACCTGAGGCTG GGGGTGCCCGTGGCAAAACCCTCCTGGTGGCTCAGGGGGTGGGCCCAGCTTTTTTGCCTC CTGCTCCACTGACTGGCTCCCGTACGCACTGTCTTCCTTCACCTTTGGGCTGGGCAGCTT GTCTCGGGTTTTTGGACCCCTCAGCAGCCTCACTCCCTCCTTTAGGCCCATGTCAAACAG GGCCTCCAGTAAACCTGCCAGGTCCCCGCCAGCCAGCTCGTAACTGCGCAGGAGGCTGCC ACTGGGTGAGGTTGTCTGTCGGTACGTGTCTACCAGGCTGCGCAGCCCCAGACGCTCTGC CAGCTCTGCCCAGCTGCCCTGGGCTTTTGGCCCGTCTAGCAGCTGCTCCAGGTTCTGCAG AGCTGTATCACCAAGTGACAGTCCCGGCCCTGCTGGGCTGGGCGGGGTCAGGGGTGGCTT CATGGGGTTCTGAGCAGCATCTAGCAGCAAGGGCTTCACCTTGGTGCTGCAAGTGAGGTC AAGAGGCGTGTGGCCCCGGAAGCTGCTTCGGGTGGCCTTCTCAGGCCTTTAAAGTCCGAT CGCTTTAAAGTACGGGGTGGAAGCAGGGGCCACAGAGTTTTTTCTTCTTCTTTGGTTGTA CCCCCACTCCTCTAGGAAGCGGTTGAGGTTCTCCACCCCCTATACATCCACAGCATGTGT GTCCCACACCACAGGTATTTACTTTACCATTTAACAACCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002502 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002502.2, NP_002493.2 |
| RefSeq Size | 3001 bp |
| RefSeq ORF | 2802 bp |
| Locus ID | 4791 |
| UniProt ID | Q00653 |
| Domains | RHD, DEATH, ANK, IPT |
| Protein Families | Transcription Factors |
| Protein Pathways | MAPK signaling pathway, Pathways in cancer |
| Gene Summary | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2, 3, and 4 encode the same isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213313 | NFKB2 (Myc-DDK-tagged)-Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2 |
CNY 6,584.00 |
|
| RC213313L1 | Lenti ORF clone of Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2, Myc-DDK-tagged |
CNY 8,984.00 |
|
| RC213313L2 | Lenti ORF clone of Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC213313L3 | Lenti ORF clone of Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213313L4 | Lenti ORF clone of Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2, mGFP tagged |
CNY 8,984.00 |
|
| RG213313 | NFKB2 (tGFP-tagged) - Human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2), transcript variant 2 |
CNY 8,184.00 |
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