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LOX (NM_002317) Human Untagged Clone
CAT＃: SC118674
LOX (untagged)-Human lysyl oxidase (LOX), transcript variant 1
CNY 5,488.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AAT10 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118674 sequence for NM_002317 edited (data generated by NextGen Sequencing)
ATGCGCTTCGCCTGGACCGTGCTCCTGCTCGGGCCTTTGCAGCTCTGCGCGCTAGTGCAC TGCGCCCCTCCCGCCGCCGGCCAACAGCAGCCCCCGCGCGAGCCGCCGGCGGCTCCGGGC GCCTGGCGCCAGCAGATCCAATGGGAGAACAACGGGCAGGTGTTCAGCTTGCTGAGCCTG GGCTCACAGTACCAGCCTCAGCGCCGCCGGGACCCGGGCGCCGCCGTCCCTGGTGCAGCC AACGCCTCCGCCCAGCAGCCCCGCACTCCGATCCTGCTGATCCGCGACAACCGCACCGCC GCGGCGCGAACGCGGACGGCCGGCTCATCTGGAGTCACCGCTGGCCGCCCCAGGCCCACC GCCCGTCACTGGTTCCAAGCTGGCTACTCGACATCTAGAGCCCGCGAAGCTGGCGCCTCG CGCGCGGAGAACCAGACAGCGCCGGGAGAAGTTCCTGCGCTCAGTAACCTGCGGCCGCCC AGCCGCGTGGACGGCATGGTGGGCGACGACCCTTACAACCCCTACAAGTACTCTGACGAC AACCCTTATTACAACTACTACGATACTTATGAAAGGCCCAGACCTGGGGGCAGGTACCGG CCCGGATACGGCACTGGCTACTTCCAGTACGGTCTCCCAGACCTGGTGGCCGACCCCTAC TACATCCAGGCGTCCACGTACGTGCAGAAGATGTCCATGTACAACCTGAGATGCGCGGCG GAGGAAAACTGTCTGGCCAGTACAGCATACAGGGCAGATGTCAGAGATTATGATCACAGG GTGCTGCTCAGATTTCCCCAAAGAGTGAAAAACCAAGGGACATCAGATTTCTTACCCAGC CGACCAAGATATTCCTGGGAATGGCACAGTTGTCATCAACATTACCACAGTATGGATGAG TTTAGCCACTATGACCTGCTTGATGCCAACACCCAGAGGAGAGTGGCTGAAGGCCACAAA GCAAGTTTCTGTCTTGAAGACACATCCTGTGACTATGGCTACCACAGGCGATTTGCATGT ACTGCACACACACAGGGATTGAGTCCTGGCTGTTATGATACCTATGGTGCAGACATAGAC TGCCAGTGGATTGATATTACAGATGTAAAACCTGGAAACTATATCCTAAAGGTCAGTGTA AACCCCAGCTACCTGGTTCCTGAATCTGACTATACCAACAATGTTGTGCGCTGTGACATT CGCTACACAGGACATCATGCGTATGCCTCAGGCTGCACAATTTCACCGTATTAG Clone variation with respect to NM_002317.5 >OriGene 5' read for NM_002317 unedited
GTCAGATTTGTAAACGACTTCACTATAGGCGGCCCGCGAATTCGCACGAGGCAGACACTG CCCGCTCTCCGGGACTGCCGCGCCGCTCCCCGTTGCCTTCCAGGACTGAGAAAGGGGAAA GGGAAGGGTGCCACGTCCGAGCAGCCGCCTTGACTGGGGAAGGGTCTGAATCCCACCCTT GGCATTGCTTGGTGGAGACTGAGATACCCGTGCTCCGCTCGCCTCCTTGGTTGAAGATTT CTCCTTCCCTCACGTGATTTGAGCCCCGTTTTTATTTTCTGTGAGCCACGTCCTCCTCGA GCGGGGTCAATCTGGCAAAAGGAGTGATGCGCTTCGCCTGGACCGTGCTCCTGCTCGGGC CTTTGCAGCTCTGCGCGCTAGTGCACTGCGCCCCTCCCGCCGCCGGCCAACAGCAGCCCC CGCGCGAGCCGCCGGCGGCTCCGGGCGCCTGGCGCCAGCAGATCCAATGGGAGAACAACG GGCAGGTGTTCAGCTTGCTGAGCCTGNGCTCACAGTACCAGCCTCAGCGCCGCCGGGACC CGGGCGCCGCCGTCCCTGGTGCAGCCAACGCCTCCGCCCAGCAGCCCCGCACTCCGATCC TGCTGATCCGCGACAACCGCACCGCCGCGGCGCGAACGCGGACGGCCGGCTCATCTGGAG TCACCGCTGGCCGCCCCAGGCCCACCGCCCGTCACTGGTTCCAAGCTGCCTACTCGACAT CTAGAGCCCCGCGAAGCTGGCGCCTCGCGCGCCGGAGACCAGACAGCGCCCGGGAGAAGT TCCTGCGCTCAGTAACCCGCGGCCGCCCAACCGCGTGGACGGCATGTTGGGCCGACGACC CTTACAACCCCTACAAGTACTCTTGACGACAACCCTTTTATACCACTTACTACGATACTC ATTGAAAGGCCCCAACCTGGGGGCCAGTCCCCGGCCCG >OriGene 3' read for NM_002317 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAAGATCAAATATGTAATTAC AGAATTGAAACACTGTGTTAATTCACAAAGTGATGTAAATAATAAACATTAAAAATTTCC CAAGTAATGATGACTTAAGCGTTCAAAATCCAGTTATGTGCTTTGTTATTGAAAACAGTC CAAACAAAAATTCTTTTGTTGTTTTCTGTTCTCTTTTTCAAAATACATAAATCCTACTGA AGTTAGTCTATTTTTTCCCACTTCAGAACACCAGGCACTGATTTATCCATTGGGAGTTTT GCTTTGCCTTCTAATACGGTGAAATTGTGCAGCCTGAGGCATACGCATGATGTCCTGTGT AGCGAATGTCACAGCGCACAACATTGTTGGTATAGTCAGATTCAGGAACCAGGTAGCTGG GGTTTACACTGACCTTTAGGATATAGTTTCCAGGTTTTACATCTGTAATATCAATCCACT GGCAGTCTATGTCTGCACCATAGGTATCATAACAGCCAGGACTCAATCCCTGTGTGTGTG CAGTACATGCAAATCGCCTGTGGTAGCCATAGTCACAGGATGTGTCTTCAAGACAGAAAC TTGCTCTGTGGCCTTCAGCCACTCTCCTCTGGGTGTTGGCATCAAGCAGGTCATAGTGGC TAAACTCATCCATACTGTGGTAATGCTGATGACAACTGTGCCATTCCCAGGAATATCTTG GTCGGCTGGGTAAGACATCTGATGTCCCTTGGTTTTTCACTCTTTGGGGAAATCTGAGCA GCACCCTGTGATCATAATCTCTGACATCTGGCCTGTATGCTGTACTGGCCAGACAAGTTT TCTCCGCCGCGCATCTCAAGTTGACATGGACATCTTCTGACGTACGTGAACGCCTGGTGT ATTAGGGGTCGCCCCCAGGCTGGGAAACCGCACTGGAAGTACCAGGCCGTATTCGGGCCG CACCTGCCCCCAGCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002317 |
| Insert Size | 1870 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002317.3, NP_002308.2 |
| RefSeq Size | 1946 bp |
| RefSeq ORF | 1254 bp |
| Locus ID | 4015 |
| UniProt ID | P28300 |
| Domains | Lysyl_oxidase |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Dysregulation of Lysyl Oxidase Expression in Lesions and Endometrium of Women With Endometriosis
,Ruiz, LA;Báez-Vega, PM;Ruiz, A;Peterse, DP;Monteiro, JB;Bracero, N;Beauchamp, P;Fazleabas, AT;Flores, I;,
Reprod Sci
,PubMed ID 25963914
[LOX]
|
|
Nuclear translocation of lysyl oxidase is promoted by interaction with transcription repressor p66ß
,Okkelman, IA;Sukaeva, AZ;Kirukhina, EV;Korneenko, TV;Pestov, NB;,
Cell Tissue Res.
,PubMed ID 25118846
[LOX]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213323 | LOX (Myc-DDK-tagged)-Human lysyl oxidase (LOX), transcript variant 1 |
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|
| RC213323L1 | Lenti ORF clone of Human lysyl oxidase (LOX), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
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| RC213323L2 | Lenti ORF clone of Human lysyl oxidase (LOX), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RC213323L3 | Lenti ORF clone of Human lysyl oxidase (LOX), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC213323L4 | Lenti ORF clone of Human lysyl oxidase (LOX), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG213323 | LOX (tGFP-tagged) - Human lysyl oxidase (LOX), transcript variant 1 |
CNY 7,088.00 |
