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NUR77 (NR4A1) (NM_002135) Human Untagged Clone
CAT＃: SC118806
NR4A1 (untagged)-Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1
CNY 6,688.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002135, the custom clone sequence may differ by one or more nucleotides
ATGCCCTGTATCCAAGCCCAATATGGGACACCAGCACCGAGTCCGGGACCCCGTGACCACCTGGCAAGCG ACCCCCTGACCCCTGAGTTCATCAAGCCCACCATGGACCTGGCCAGCCCCGAGGCAGCCCCCGCTGCCCC CACTGCCCTGCCCAGCTTCAGCACCTTCATGGACGGCTACACAGGAGAGTTTGACACCTTCCTCTACCAG CTGCCAGGAACAGTCCAGCCATGCTCCTCAGCCTCCTCCTCGGCCTCCTCCACATCCTCGTCCTCAGCCA CCTCCCCTGCCTCTGCCTCCTTCAAGTTCGAGGACTTCCAGGTGTACGGCTGCTACCCCGGCCCCCTGAG CGGCCCAGTGGATGAGGCCCTGTCCTCCAGTGGCTCTGACTACTATGGCAGCCCCTGCTCGGCCCCGTCG CCCTCCACGCCCAGCTTCCAGCCGCCCCAGCTCTCTCCCTGGGATGGCTCCTTCGGCCACTTCTCGCCCA GCCAGACTTACGAAGGCCTGCGGGCATGGACAGAGCAGCTGCCCAAAGCCTCTGGGCCCCCACAGCCTCC AGCCTTCTTTTCCTTCAGTCCTCCCACCGGCCCCAGCCCCAGCCTGGCCCAGAGCCCCCTGAAGTTGTTC CCCTCACAGGCCACCCACCAGCTGGGGGAGGGAGAGAGCTATTCCATGCCTACGGCCTTCCCAGGTTTGG CACCCACTTCTCCACACCTTGAGGGCTCGGGGATACTGGATACACCCGTGACCTCAACCAAGGCCCGGAG CGGGGCCCCAGGTGGAAGTGAAGGCCGCTGTGCTGTGTGTGGGGACAACGCTTCATGCCAGCATTATGGT GTCCGCACATGTGAGGGCTGCAAGGGCTTCTTCAAGCGCACAGTGCAGAAAAACGCCAAGTACATCTGCC TGGCTAACAAGGACTGCCCTGTGGACAAGAGGCGGCGAAACCGCTGCCAGTTCTGCCGCTTCCAGAAGTG CCTGGCGGTGGGCATGGTGAAGGAAGTTGTCCGAACAGACAGCCTGAAGGGGCGGCGGGGCCGGCTACCT TCAAAACCCAAGCAGCCCCCAGATGCCTCCCCTGCCAATCTCCTCACTTCCCTGGTCCGTGCACACCTGG ACTCAGGGCCCAGCACTGCCAAACTGGACTACTCCAAGTTCCAGGAGCTGGTGCTGCCCCACTTTGGGAA GGAAGATGCTGGGGATGTACAGCAGTTCTACGACCTGCTCTCCGGTTCTCTGGAGGTCATCCGCAAGTGG GCGGAGAAGATCCCTGGCTTTGCTGAGCTGTCACCGGCTGACCAGGACCTGTTGCTGGAGTCGGCCTTCC TGGAGCTCTTCATCCTCCGCCTGGCGTACAGGTCTAAGCCAGGCGAGGGCAAGCTCATCTTCTGCTCAGG CCTGGTGCTACACCGGCTGCAGTGTGCCCGTGGCTTCGGGGACTGGATTGACAGTATCCTGGCCTTCTCA AGGTCCCTGCACAGCTTGCTTGTCGATGTCCCTGCCTTCGCCTGCCTCTCTGCCCTTGTCCTCATCACCG ACCGGCATGGGCTGCAGGAGCCGCGGCGGGTGGAGGAGCTGCAGAACCGCATCGCCAGCTGCCTGAAGGA GCACGTGGCAGCTGTGGCGGGCGAGCCCCAGCCAGCCAGCTGCCTGTCACGTCTGTTGGGCAAACTGCCC GAGCTGCGGACCCTGTGCACCCAGGGCCTGCAGCGCATCTTCTACCTCAAGCTGGAGGACTTGGTGCCCC CTCCACCCATCATTGACAAGATCTTCATGGACACGCTGCCCTTCTGA >OriGene 5' read for NM_002135 unedited
AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAAGACGAAACTTGGGGGAGTGC ACAGAAGAACTTCGGGAGCGCACGCGGGACCAGGGACCAGGCTGAGACTCGGGGCGCCAG TCCGGGCAGGGGCAGCGGGAGCCGGCCGGAGATGCCCTGTATCCAAGCCCAATATGGGAC ACCAGCACCGAGTCCGGGACCCCGTGACCACCTGGCAAGCGACCCCCTGACCCCTGAGTT CATCAAGCCCACCATGGACCTGGCCAGCCCCGAGGCAGCCCCCGCTGCCCCCACTGCCCT GCCCAGCTTCAGCACCTTCATGGACGGCTACACAGGAGAGTTTGACACCTTCCTCTACCA GCTGCCAGGAACAGTCCAGCCATGCTCCTCAGCCTCCTCCTCGGCCTCCTCCACATCCTC GTCCTCAGCCACCTCCCCTGCCTCTGCCTCCTTCAAGTTCGAGGACTTCCAGGTGTACGG CTGCTACCCCGGCCCCCTGAGCGGCCCAGTGGATGAGGCCCTGTCCTCCAGTGGCTCTGA CTACTATGGCAGCCCCTGCTCGGCCCCGTCGCCCTCCACGCCCAGCTTCCAGCCGCCCCA GCTCTCTCCCTGAGATGGCTCCTTCGGCCACTTCTCGCCCAGCCAGACTTACGAAAGCCT GCGGGCATGGACAGAGCAGCTGCCCAAAGCCTCTGGGCCCNCACAGCCTNCAGCCTTCTT TTNCTTCAGTCCTACCACCGGCNCCCAGCCCCAGTCTGGCCCANAGCCCCCCTGAAAGGT GTCCCCTCACAGGGCACCCACCAGCTGGGGGAGGGGAGAGAGCTATTNCATGCCTACGGC NCTTNNCAGTTTGGCACCCACTCTCCACACCTTGAGGGCTCGGGGATCTGGATACACCCG TGACCTCACCAAGGCCCGGANCGNGCCCCAGNTGNAANTGAAGCCCCTGTGCTGGTGTGG GACAACCTTCATGCACATTATGTGNCGC >OriGene 3' read for NM_002135 unedited
CAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTACATGGCTA TTTTTTATTCAATATATTAAATATATTAATCCAAAAAAGTCACATACTATAAATCCAGGA AAATACACAAATATAAATGTCAAAATCTGTCATTTGTCTTCTTCCTAAAGTGACAGTTTA TGTACATGTGGAAGGAGGGTAGGAAAAAAGAGCCAGCAGGAGGCTGGAAAGGCTGCCCAA AAAGGCGGGGCCCATCCCTTCCTCCCAGCCCCGCTCCCACCTAAAGCTCTTTCTTCCTGT ATTTACAGCAGCACTGGGCTTATTTACAGCACGGGGCTATGTGTTAAAAACGGTTTATCT TACAAAAAACATAAAGGCCGGGGCCAGGCTGGGGGGGATAAAACAAATCGTGGGGTCACC CCCATGAAGGCATCCCCCTCCCCAAGGGCTTGAGCTCCCTGCAAACCTCCTGGAACAGGT GAAAAGGTGGAGTCATTCTGCAGCTCAAGCCCAGGCTTGGGGGTGCTCTGGGGGTCCGTG GACTAAAGGCACATGGGGTGGCATATGAGAGTGCGCATGTGCACACGTGTTCCCAGGCAG GGGTCAGAAGGGCACCGTGCCCATGAAGATCTTGTCAATGATGGGTGGAGGGGGCCCCAG TCCTCCAACTTTGAGTAAATAAGCGCTGCACGCCCTGGTGCACAGGTTCCCCACCTCGGC CATTTGCCCACAAATGTTACAGCATTTGTCTGTTGGGCCTTTCCACCAATTTGCCACGGG TTCTTTAGCCACTGGCAATGCGGTTTTCACCTCTTCCCCGCCGCGGTTCTTAACCCATCC GCCGGGTAAGGACAAGCCCATAGTTTGGAAGCAGGAACCCCAACCACTGGTAGGGACTTG AGAAGCCAATCCGTTATACCCCCCCCAACCCCGGCCTCTACCCGGTTTTCCACCCCCGAC CAAAAAAATTTTCTCCCTCGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002135 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002135.3, NP_002126.2 |
| RefSeq Size | 2699 bp |
| RefSeq ORF | 1797 bp |
| Locus ID | 3164 |
| UniProt ID | P22736 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (1) differs in the 5' structure, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 4. The encoded isoform (1) has a shorter N-terminus compared to isoform 3. Variants 1 and 2 encode the same isoform. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77–based mechanism
,Jianguang Chen, Warren Fiskus, Kelly Eaton, Pravina Fernandez, Yongchao Wang, Rekha Rao, Pearl Lee, Rajeshree Joshi, Yonghua Yang, Ravindra Kolhe, Ramesh Balusu, Prasanthi Chappa, Kavita Natarajan, Anand Jillella, Peter Atadja, and Kapil N. Bhalla,
Blood, Apr 2009; 113: 4038 - 4048.
[NR4A1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202202 | NR4A1 (Myc-DDK-tagged)-Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1 |
CNY 6,680.00 |
|
| RC202202L1 | Lenti ORF clone of Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1, Myc-DDK-tagged |
CNY 9,080.00 |
|
| RC202202L2 | Lenti ORF clone of Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1, mGFP tagged |
CNY 9,080.00 |
|
| RC202202L3 | Lenti ORF clone of Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1, Myc-DDK-tagged |
CNY 9,080.00 |
|
| RC202202L4 | Lenti ORF clone of Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1, mGFP tagged |
CNY 9,080.00 |
|
| RG202202 | NR4A1 (tGFP-tagged) - Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1 |
CNY 8,280.00 |
|
| SC322380 | NR4A1 (untagged)-Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 1 |
CNY 6,688.00 |
