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DDB1 (NM_001923) Human Untagged Clone
CAT＃: SC118946
DDB1 (untagged)-Human damage-specific DNA binding protein 1, 127kDa (DDB1)
CNY 7,944.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001923, the custom clone sequence may differ by one or more nucleotides
ATGTCGTACAACTACGTGGTAACGGCCCAGAAGCCCACCGCCGTGAACGGCTGCGTGACCGGACACTTTA CTTCGGCCGAAGACTTAAACCTGTTGATTGCCAAAAACACGAGATTAGAGATCTATGTGGTCACCGCCGA GGGGCTTCGGCCCGTCAAAGAGGTGGGCATGTATGGGAAGATTGCGGTCATGGAGCTTTTCAGGCCCAAG GGGGAGAGCAAGGACCTGCTGTTTATCTTGACAGCGAAGTACAATGCCTGCATCCTGGAGTATAAACAGA GTGGCGAGAGCATTGACATCATTACGCGAGCCCATGGCAATGTCCAGGACCGCATTGGCCGCCCCTCAGA GACCGGCATTATTGGCATCATTGACCCTGAGTGCCGGATGATTGGCCTGCGTCTCTATGATGGCCTTTTC AAGGTTATTCCACTAGATCGCGATAATAAAGAACTCAAGGCCTTCAACATCCGCCTGGAGGAGCTGCATG TCATTGATGTCAAGTTCCTATATGGTTGCCAAGCACCTACTATTTGCTTTGTCTACCAGGACCCTCAGGG GCGGCACGTAAAAACCTATGAGGTGTCTCTCCGAGAAAAGGAATTCAATAAGGGCCCTTGGAAACAGGAA AATGTCGAAGCTGAAGCTTCCATGGTGATCGCAGTCCCAGAGCCCTTTGGGGGGGCCATCATCATTGGAC AGGAGTCAATCACCTATCACAATGGTGACAAATACCTGGCTATTGCCCCTCCTATCATCAAGCAAAGCAC GATTGTGTGCCACAATCGAGTGGACCCTAATGGCTCAAGATACCTGCTGGGAGACATGGAAGGCCGGCTC TTCATGCTGCTTTTGGAGAAGGAGGAACAGATGGATGGCACCGTCACTCTCAAGGATCTCCGTGTAGAAC TCCTTGGAGAGACCTCTATTGCTGAGTGCTTGACATACCTTGATAATGGTGTTGTGTTTGTCGGGTCTCG CCTGGGTGACTCCCAGCTTGTGAAGCTCAACGTTGACAGTAATGAACAAGGCTCCTATGTAGTGGCCATG GAAACCTTTACCAACTTAGGACCCATTGTCGATATGTGCGTGGTGGACCTGGAGAGGCAGGGGCAGGGGC AGCTGGTCACTTGCTCTGGGGCTTTCAAGGAAGGTTCTTTGCGGATCATCCGGAATGGAATTGGAATCCA CGAGCATGCCAGCATTGACTTACCAGGCATCAAAGGATTATGGCCACTGCGGTCTGACCCTAATCGTGAG ACTGATGACACTTTGGTGCTCTCTTTTGTGGGCCAGACAAGAGTTCTCATGTTAAATGGAGAGGAGGTAG AAGAAACCGAACTGATGGGTTTCGTGGATGATCAGCAGACTTTCTTCTGTGGCAACGTGGCTCATCAGCA GCTTATCCAGATCACTTCAGCATCGGTGAGGTTGGTCTCTCAAGAACCCAAAGCTCTGGTCAGTGAATGG AAGGAGCCTCAGGCCAAGAACATCAGTGTGGCCTCCTGCAATAGCAGCCAGGTGGTGGTGGCTGTAGGCA GGGCCCTCTACTATCTGCAGATCCATCCTCAGGAGCTCCGGCAGATCAGCCACACAGAGATGGAACATGA AGTGGCTTGCTTGGACATCACCCCATTAGGAGACAGCAATGGACTGTCCCCTCTTTGTGCCATTGGCCTC TGGACGGACATCTCGGCTCGTATCTTGAAGTTGCCCTCTTTTGAACTACTGCACAAGGAGATGCTGGGTG GAGAGATCATTCCTCGCTCCATCCTGATGACCACCTTTGAGAGTAGCCATTACCTCCTTTGTGCCTTGGG AGATGGAGCGCTTTTCTACTTTGGGCTCAACATTGAGACAGGTCTGTTGAGCGACCGTAAGAAGGTGACT TTGGGCACCCAGCCCACCGTATTGAGGACTTTTCGTTCTCTTTCTACCACCAACGTCTTTGCTTGTTCTG ACCGCCCCACTGTCATCTATAGCAGCAACCACAAATTGGTCTTCTCAAATGTCAACCTCAAGGAAGTGAA CTACATGTGTCCCCTCAATTCAGATGGCTATCCTGACAGCCTGGCGCTGGCCAACAATAGCACCCTCACC ATTGGCACCATCGATGAGATCCAGAAGCTGCACATTCGCACAGTTCCCCTCTATGAGTCTCCAAGGAAGA TCTGCTACCAGGAAGTGTCCCAGTGTTTCGGGGTCCTCTCCAGCCGCATTGAAGTCCAAGACACGAGTGG GGGCACGACAGCCTTGAGGCCCAGCGCTAGCACCCAGGCTCTGTCCAGCAGTGTAAGCTCCAGCAAGCTG TTCTCCAGCAGCACTGCTCCTCATGAGACCTCCTTTGGAGAAGAGGTGGAGGTGCACAACCTACTTATCA TTGACCAACACACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAATATGCCCTCAGTCTGGT TTCCTGCAAGCTGGGCAAAGACCCCAACACTTACTTCATTGTGGGCACAGCAATGGTGTATCCTGAAGAG GCAGAGCCCAAGCAGGGTCGCATTGTGGTCTTTCAGTATTCGGATGGAAAACTACAGACTGTGGCTGAAA AGGAAGTGAAAGGGGCCGTGTACTCTATGGTGGAATTTAACGGGAAGCTGTTAGCCAGCATCAATAGCAC GGTGCGGCTCTATGAGTGGACAACAGAGAAGGAGCTGCGCACTGAGTGCAACCACTACAACAACATCATG GCCCTCTACCTGAAGACCAAGGGCGACTTCATCCTGGTGGGCGACCTTATGCGCTCAGTGCTGCTGCTTG CCTACAAGCCCATGGAAGGAAACTTTGAAGAGATTGCTCGAGACTTTAATCCCAACTGGATGAGTGCTGT GGAAATCTTGGATGATGACAATTTTCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAAAAGGAT AGCGCTGCCACCACTGACGAGGAGCGGCAGCACCTCCAGGAGGTTGGTCTTTTCCACCTGGGCGAGTTTG TCAATGTCTTTTGCCACGGCTCTCTGGTAATGCAGAATCTGGGTGAGACTTCCACCCCCACACAAGGCTC GGTGCTCTTCGGCACGGTCAACGGCATGATAGGGCTGGTGACCTCACTGTCAGAGAGCTGGTACAACCTC CTGCTGGACATGCAGAATCGACTCAATAAAGTCATCAAAAGTGTGGGGAAGATCGAGCACTCCTTCTGGA GATCCTTTCACACCGAGCGGAAGACAGAACCAGCCACAGGTTTCATCGACGGTGACTTGATTGAGAGTTT CCTGGATATTAGCCGCCCCAAGATGCAGGAGGTGGTGGCAAACCTACAGTATGACGATGGCAGCGGTATG AAGCGAGAGGCCACTGCAGACGACCTCATCAAGGTTGTGGAGGAGCTAACTCGGATCCATTAG >OriGene 5' read for NM_001923 unedited
TCACTATTTGTATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGCTGGAGGCT GCAGGGCTGACGGCTCTCCTGGCTCATTAAGGTTCCCTACGGAGAAATACTGGTTTTGTG TTTGAGGTTCGAATTTGTAGAGCAATAGGGGCACTAATAACGTTGGGCAAGCAGACCGGT GGGCCCTTTGAAGTCTGAAGAATCAACGCTCAAAAGGGAGGAGTGTCGCGCTCGAGTCCC GACGGGCCGCTCCAAGCCTCGACATGTCGTACAACTACGTGGTAACGGCCCAGAAGCCCA CCGCCGTGAACGGCTGCGTGACCGGACACTTTACTTCGGCCGAAGACTTAAACCTGTTGA TTGCCAAAAACACGAGATTAGAGATCTATGTGGTCACCGCCGAGGGGCTTCGGCCCGTCA AAGAGGTGGGCATGTATGGGAAGATTGCGGTCATGGAGCTTTTCAGGCCCAAGGGGGAGA GCAAGGACCTGCTGTTTATCTTGACAGCGAAGTACAATGCCTGCATCCTGNAGTATAAAC AGAGTGGCGAGAGCATTGACATCATTACGCGAGCCCATGGCAATGTCCAGGACCGCATTG GCCGCCCCTCACAGACCGGCATTATTGGCATCATTGACCCTGAGTGCCGGATGATTGGCC CTGCGCTCTATGATGGCCTTTTAAGGTTATTCACTAGATCGCGATATTAAGAACTCAAGG CCTTCACATCCGCCTGGAGGAACTGCATGCCCATGACAGCCAGCTCCTCATTGGTTGCCC AAGCACCTACTATTTGCTTTGGTAACAAGACCCTCAGGGGCGGGACGTAAAAAACTATGA GGGGTTTTCCCGAAAAAGGAATTCTATAAAGGCCCTTTGGAAAAAGGAAAATGTCCAACC TGAACCTTCCTGGGGAACGCATACCCCAACACCTTTG >OriGene 3' read for NM_001923 unedited
TCTTTTTTGGTAACTAGAACAACATTACATCCCCACCTTTTTTTCCAAAAGCAGTTTGCG AGACAAAAGGCTGTGGCGTGGGGATCATCCACCATCTCCAGGTTTTACACCCAGGCTACC CATGGCTTGGCAGTCAGGCCTCTAGGCCTGATGCTCTCAGAGGCAATAGAAGAAAAGTAA AAGGAAGGTCTCACTTCACAGACAATGAAACCCTCCTAACCCTCTTCCCCACTACCCACA ACTCCCTACACTGCCAATCTAAATAAAAAGAGGACAATGCATGAGTGTGAGATACCACAT ACACACACACACATACACACACACACACGCACAGCTTCCTTTCAGCCAAAGAACTGCAAA ATCCTTCCCCGGAAGGAGGACAACTGGCAACACCAATCAAGGCTTGGTGGTCTAAGGTGA TGGCTGGAATCATGTGAGACTGGTAAAAATCCAGGGAGAAAATGTTTCACCTTCAGCTCA TTCCCAAGTCTCTATGAAGCCCGCCCCACTTCCACATAGGGGAACTGTGGCTCTGGNGGC AGCTGGCTTANGGAAAGGCCTCCCATGGCCAAAAAGACNATGGTGGAGAGGAGGGGGAGG GCANCANGGCANAGCCTTTGNGGAGGGTCAGCAAAGGGGCCCNCTGCCCCTTGCTAATGG ATCCCGAGTAGCTCCTNCACAACCTTGATGAGGTCGTCTGCAGTGGCCTCTCGCTTCATA CCGCTGNCATCGTCATACTGTNAGGGTTGCCACCACCTNCTGCATCTTGGGGGCGGCTAT ATNCAGNAAACTCTCAATCAAGTCACCGTCGATGAAACCTGTNNGCTGGTCTGTCTTTCC GCTCGTGTGAAAGGATCTNCANAANNGATGCTCGATCTTNCCCACACTTTGATGACTTTA ATGANTCGATNCTGCATGTCCAGCCAGAAGTTGTACCAGCCTNTGACAGTGAGGTCACAG CCTTTAATGCCGNTGACCGTGCCGAAACCACCGAGCCTGGGTGGGGTGGGAGTCTCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001923 |
| Insert Size | 423 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001923.2, NP_001914.2 |
| RefSeq Size | 4221 bp |
| RefSeq ORF | 3423 bp |
| Locus ID | 1642 |
| UniProt ID | Q16531 |
| Domains | CPSF_A |
| Protein Families | Druggable Genome |
| Protein Pathways | Nucleotide excision repair, Ubiquitin mediated proteolysis |
| Gene Summary | The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208372 | DDB1 (Myc-DDK-tagged)-Human damage-specific DNA binding protein 1, 127kDa (DDB1) |
CNY 11,904.00 |
|
| RC208372L1 | Lenti ORF clone of Human damage-specific DNA binding protein 1, 127kDa (DDB1), Myc-DDK-tagged |
CNY 14,304.00 |
|
| RC208372L2 | Lenti ORF clone of Human damage-specific DNA binding protein 1, 127kDa (DDB1), mGFP tagged |
CNY 14,304.00 |
|
| RC208372L3 | Lenti ORF clone of Human damage-specific DNA binding protein 1, 127kDa (DDB1), Myc-DDK-tagged |
CNY 14,304.00 |
|
| RC208372L4 | Lenti ORF clone of Human damage-specific DNA binding protein 1, 127kDa (DDB1), mGFP tagged |
CNY 7,600.00 |
|
| RG208372 | DDB1 (tGFP-tagged) - Human damage-specific DNA binding protein 1, 127kDa (DDB1) |
CNY 13,504.00 |
