Carboxypeptidase H (CPE) (NM_001873) Human Untagged Clone

CAT#: SC118995

CPE (untagged)-Human carboxypeptidase E (CPE)



  "NM_001873" in other vectors (6)

CNY 5,488.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-CPE Antibody - N-terminal region
    • 100 ul

CNY 5,250.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CPH; IDDHH
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118995 sequence for NM_001873 edited (data generated by NextGen Sequencing)
ATGGCCGGGCGAGGGGGCAGCGCGCTGCTGGCTCTGTGCGGGGCACTGGCTGCCTGCGGG
TGGCTCCTGGGCGCCGAAGCCCAGGAGCCCGGGGCGCCCGCGGCGGGCATGAGGCGGCGC
CGGCGGCTGCAGCAAGAGGACGGCATCTCCTTCGAGTACCACCGCTACCCCGAGCTGCGC
GAGGCGCTCGTGTCCGTGTGGCTGCAGTGCACCGCCATCAGCAGGATTTACACGGTGGGG
CGCAGCTTCGAGGGCCGGGAGCTCCTGGTCATCGAGCTGTCCGACAACCCTGGCGTCCAT
GAGCCTGGTGAGCCTGAATTTAAATACATTGGGAATATGCATGGGAATGAGGCTGTTGGA
CGAGAACTGCTCATTTTCTTGGCCCAGTACCTATGCAACGAATACCAGAAGGGGAACGAG
ACAATTGTCAACCTGATCCACAGTACCCGCATTCACATCATGCCTTCCCTGAACCCAGAT
GGCTTTGAGAAGGCAGCGTCTCAGCCTGGTGAACTCAAGGACTGGTTTGTGGGTCGAAGC
AATGCCCAGGGAATAGATCTGAACCGGAACTTTCCAGACCTGGATAGGATAGTGTACGTG
AATGAGAAAGAAGGTGGTCCAAATAATCATCTGTTGAAAAATATGAAGAAAATTGTGGAT
CAAAACACAAAGCTTGCTCCTGAGACCAAGGCTGTCATTCATTGGATTATGGATATTCCT
TTTGTGCTTTCTGCCAATCTCCATGGAGGAGACCTTGTGGCCAATTATCCATATGATGAG
ACGCGGAGTGGTAGTGCTCACGAATACAGCTCCTCCCCAGATGACGCCATTTTCCAAAGC
TTGGCCCGGGCATACTCTTCTTTCAACCCGGCCATGTCTGACCCCAATCGGCCACCATGT
CGCAAGAATGATGATGACAGCAGCTTTGTAGATGGAACCACCAACGGTGGTGCTTGGTAC
AGCGTACCTGGAGGGATGCAAGACTTCAATTACCTTAGCAGCAACTGTTTTGAGATCACC
GTGGAGCTTAGCTGTGAGAAGTTCCCACCTGAAGAGACTCTGAAGACCTACTGGGAGGAT
AACAAAAACTCCCTCATTAGCTACCTTGAGCAGATACACCGAGGAGTTAAAGGATTTGTC
CGAGACCTTCAAGGTAACCCAATTGCGAATGCCACCATCTCCGTGGAAGGAATAGACCAC
GATGTTACATCCGCAAAGGATGGTGATTACTGGAGATTGCTTATACCTGGAAACTATAAA
CTTACAGCCTCAGCTCCAGGCTATCTGGCAATAACAAAGAAAGTGGCAGTTCCTTACAGC
CCTGCTGCTGGGGTTGATTTTGAACTGGAGTCATTTTCTGAAAGGAAAGAAGAGGAGAAG
GAAGAATTGATGGAATGGTGGAAAATGATGTCAGAAACTTTAAATTTTTAA

Clone variation with respect to NM_001873.2
>OriGene 5' read for NM_001873 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTCCCGGACGCCAT
TTGGCTGTTGACGTGGTTCCGAGCCAGCAAATAACGCCAGCAGCCCTCCCAGATCCACGC
CGGCCCGTCTCTCCGCCGGCCCCCTCCTCGCAGTGGTTTCTCCTGCAGCTCCCCTGGGCT
CCGCGGCCAGTAGTGCAGCCCGTGGAGCCGCGGCTTTGCCCGTCTCCTCTGGGTGGCCCC
AGTGCGCGGGCTGACACTCATTCAGCCGGGGAAGGTGAGGCGAGTAGAGGCTGGTGCGGA
ACTTGCCGCCCCCAGCAGCGCCGGCGGGCTAAGCCCAGGGCCGGGCAGACAAAAGAGGCC
GCCCGCGTAAGAAGGCACGGCCGGCGGCGGCGGAGCGCATCGATGGCCGGGCGAGGGGGC
AGCGCGCTGCTGGCTCTGTGCGGGGCACTGGCTGCCTGCGGGTGGCTCCTGGGCGCCGAA
GCCCAGGAGCCCGGGGCGCCCGCGGCGGGCATGAGGCGGCGCCGGCGGCTGCAGCAAGAG
GACGGCATCTCCTTCGAGTACCACCGCTACCCCGAGCTGCGCGAGGCGCTCGTGTCCGTG
TGGCTGCAGTGCACCGCCATCAGCAGGATTTACACGGTGGGGCGCAGCTTCGAGGGCCGG
GAGCTCCTGGTCATCGAGCTGTCCGACAACCCTGGCGTCCATGAGCCTGGTGAGCCTGAA
TTTAAATACATTGGGAATATGCATGGGAATGAGGCTGTTGGACGAGAACTGCTCATTNTC
TTGCCCAGTACCCTATGCACGAATACCAGAGGGGAACGAGACANNTGTCACCTGATCACA
GTACCCGCATTACATCATGCCTTCCCTGAAACCAGATGCT
>OriGene 3' read for NM_001873 unedited
TAGTCGAGTTTTTTTTTCTTTTTTTTAACCTTTATTCATTCAGATTGCAATTCTGGGCCA
CTCTACAACCAAGAGAAAACCCTAAACTTTTAAGTAGTGTTAACGGACTACATAATATAA
TAGTATTGCTCCTATATGTACAAGCAAGAAGTCAATTTTTATTCTTTTCATAAAACCTCT
TTGTAAACATGTACCTTTTCTTCCCATCAAAAATGCATTAACAAGATCATGCTTATAGTT
AGTCAGCACAAGAAAAAAACGACAATTTATACTGAACTATTTAAGTCTTGCAGTAGAGTG
CTCACAACTCCGAGCTGTATCTGTTAACCTTTTCAATAGCATTCATTATGTGACATTGTC
ACCAATTACAGTAAAAGAACTTCACTAATTTTTGAAAGCTAGAATTACTCAAAAAATTCT
GCATTGTAAATAATACCAGGAATATTGCATTTAAGCCTAGGATGGCAAAATTACTTAAAT
CTTTTCTATACTTTTTTGTGTAATATAGGTAGGAAAATGAATACTATATAAGAGAATGAA
ATATATCAAGTTCTTTATATTTTTACCTAAGAGGCTATTTATCTTAAGGAAAGTTGATTA
ATATTTAATGATTAAAAATAAATCAATGTTAGGATTAACTGCACAAAATCTAAAAAAAGA
CACCTTACATCATACTACTTATATAGATAGATTTAAAGCAGCTACCTAGAGCCCTTTTAA
AAATTAAAGTTTTGGACNTATTTTCCACCATTCATCAATGTTTCCTCTCCCTTCTTTCCT
TTAAAAAAGGACTCCCTTCAAAACAACCCCAACAGCAGGGCTGTAAGAACCGCCACCTTT
CTTTGTTTTCGCCAATACCCGGAACTGAAGCCTGAACTTATAATTTCAAGGGTTAACACA
TTCCACATAATCCCATCTCTTGGGAAGTAACACGTGGGCTTTTCTCTTCACGGGAATGGG
GGCTCCCAATTGCGTTCACTCTAAGAGCCGGGACAATCTTTATACTCTCGCGGATTTGTC
TAGGACACAAGAGGGGAATNTTTGTTCCCTCCAAAGATCCTCAGATTCTTCGCGGGAGAC
TCTC
Restriction Sites NotI-NotI     
ACCN NM_001873
Insert Size 2560 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001873.1, NP_001864.1
RefSeq Size 2443 bp
RefSeq ORF 1431 bp
Locus ID 1363
UniProt ID P16870
Domains Zn_carbOpept
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Type I diabetes mellitus
Gene Summary This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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