BPGM (NM_001724) Human Untagged Clone

CAT#: SC119062

BPGM (untagged)-Human 2,3-bisphosphoglycerate mutase (BPGM), transcript variant 1



  "NM_001724" in other vectors (4)

CNY 2,400.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


BPGM rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms DPGM; ECYT8
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119062 sequence for NM_001724 edited (data generated by NextGen Sequencing)
ATGTCCAAGTACAAACTTATTATGTTAAGACATGGAGAGGGTGCTTGGAATAAGGAGAAC
CGTTTTTGTAGCTGGGTGGATCAGAAACTCAACAGCGAAGGAATGGAGGAAGCTCGGAAC
TGTGGGAAGCAACTCAAAGCGTTAAACTTTGAGTTTGATCTTGTATTCACATCTGTCCTT
AATCGGTCCATTCACACAGCCTGGCTGATCCTGGAAGAGCTAGGCCAGGAATGGGTGCCT
GTGGAAAGCTCCTGGCGTCTAAATGAGCGTCACTATGGGGCCTTGATCGGTCTCAACAGG
GAGCAGATGGCTTTGAATCATGGTGAAGAACAAGTGAGGCTCTGGAGAAGAAGCTACAAT
GTAACCCCGCCTCCCATTGAGGAGTCTCATCCTTACTACCAAGAAATCTACAACGACCGG
AGGTATAAAGTATGCGATGTGCCCTTGGATCAACTGCCACGGTCGGAAAGCTTAAAGGAT
GTTCTGGAGAGACTCCTTCCCTATTGGAATGAAAGGATTGCTCCCGAAGTATTACATGGC
AAAACCATTCTGATATCTGCTCATGGAAATAGCAGTAGGGCACTCCTAAAACACCTGGAA
GGTATCTCAGATGAAGACATCATCAACATTACTCTTCCTACTGGAGTCCCCATTCTTCTG
GAATTGGATGAAAACCTGCGTGCTGTTGGGCCTCATCAGTTCCTGGGTGACCAAGAGGCG
ATCCAAGCAGCCATTAAGAAAGTAGAAGATCAAGGAAAAGTGAAACAAGCTAAAAAATAG

Clone variation with respect to NM_001724.4
536 g=>a
>OriGene 5' read for NM_001724 unedited
TACGACTCTCTATAGGCGGTCGCGAATTCGGCACGAGGTGCTGTCCTTGAATATTAGCCC
ATTTGAAAACGCCTGGGAAGTTCAGCCATCAGTATGTCCAAGTACAAACTTATTATGTTA
AGACATGGAGAGGGTGCTTGGAATAAGGAGAACCGTTTTTGTAGCTGGGTGGATCAGAAA
CTCAACAGCGAAGGAATGGAGGAAGCTCGGAACTGTGGGAAGCAACTCAAAGCGTTAAAC
TTTGAGTTTGATCTTGTATTCACATCTGTCCTTAATCGGTCCATTCACACAGCCTGGCTG
ATCCTGGAAGAGCTAGGCCAGGAATGGGTGCCTGTGGAAAGCTCCTGGCGTCTAAATGAG
CGTCACTATGGGGCCTTGATCGGTCTCAACAGGGAGCAGATGGCTTTGAATCATGGTGAA
GAACAAGTGAGGCTCTGGAGAAGAAGCTACAATGTAACCCCGCCTCCCATTGAGGAGTCT
CATCCTTACTACCAAGANATCTACAACGACCGGAGGTATAAAGTATGCGATGTGCCCTTG
GATCAACTGCCACGGTCGGAAAGCTTCTAGGATGTTCTGGAGAGACTCCTTCCCTATTGG
AATGAAAGGATTGCTCCCGAAGTATTACATGGCAAAACCATTCTGATATCTGCTCATGGA
AATAGCAGTAGGGCACTCCTAAAACACCTGGAAGGTATCTCAGATGAAGACATCATCAAC
ATTACTCTTTCTACTGGAGTCCCCATTCTTCTGAAATTGGATGAAAACCTGCGTGCTGTT
GGGCCTCATCAGGTCCTGGGTGACCCAAGAGGCGATCCAAGCCGCCTTTTAAGAAGTNNA
AGATCCAGGAAAAGTGGAACCAGCTAAAAAATAGCCTTTCTCAACTGTTGCCTAAAAAAA
ATGCCAAAGAGTGGCCTAGGAATGGGGTATGGGGGCTGACTTTTCTTTTTTTCCCCGATT
TCT
>OriGene 3' read for NM_001724 unedited
CGGCCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCCATTTTCAGTCACTTTAT
TATCAGGAACTTTATTTTTAAACTAATTACAGGTACCCAAAGTTCAAAAAATTAAAACAA
ACCAAAATGAGAACCTCAACAGCCATAGTTGTTTATTTGCTGCTTATTCTTGTGGCCAAA
GAGGAATTCTACTAAATGTCAAATGAAGGATGTCTCTAAACTAGAAGACAAGTTAAAGGG
CCTTGTTGTCATTTCTGTCATTGTGGTGGTGGTTGTTGGCTTTCTTGGAGAAATATATCT
GTGACTTTCTCAACTAATGGGCCTCTGGCCTTAATTATCAAAGTATCCCTTTTCCTAGAG
GAAAAGACTAGTAATAAATACATACGGGATATTATCTAATATCCCTTACTGTTATCCCAG
AAAATCTTATTAAATATTAAAGTGAACTACTGATTAGAATAGTGCCTGTCAATGGTGACT
CAATAATGATTTCTTGAATGATAAATACCTTTAACTTCATCTCTACTTGTTGCTCTCCCA
TCTCAGAAACTTATGACCTTCATTAAGCCCCACTAGTTACTAGTTTGGTGACCGACTAGG
GGGCTAGCAAGAAAGCTAACTCATAAGGCTATGACATAAGCACTGAGGCATCCTAAAGCC
TTATCTGGGCCACAATAAGTTACCTAGTTACCTATACAAACTCTACTCCACAGCCTACCT
CCTGAAAATCGGGGAAAAAGAGAGAGAGTTCAGCACCCATAACACACTCCTATGCCACTT
CTTTTGCATTTCTTCTTACCACAGTTGAGAAGACTATTTTTAGCTGGNTTCACTTTTCCT
GAACTTCACTTTCTTAGGCCTGCTNGAACCGCTTTTGTCCCCCCGAACTGATAAGCCCAC
CGCCCCCAGGTTTCTACAATCCACAAAAAGGGACCCCCTAGAAAAGACGTCGAAATGGTT
CTTTCAAAACTTCAGGT
Restriction Sites NotI-NotI     
ACCN NM_001724
Insert Size 1650 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001724.3, NP_001715.1
RefSeq Size 1769 bp
RefSeq ORF 780 bp
Locus ID 669
UniProt ID P07738
Domains PGAM
Protein Families Druggable Genome
Protein Pathways Glycolysis / Gluconeogenesis, Metabolic pathways
Gene Summary 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1, 2, and 3 encode the same protein.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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