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Calmodulin (CALM2) (NM_001743) Human Untagged Clone
CAT＃: SC119076
CALM2 (untagged)-Human calmodulin 2 (phosphorylase kinase, delta) (CALM2)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CALM; CALML2; caM; CAM1; CAM3; CAMC; CAMII; CAMIII; LQT15; PHKD; PHKD2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001743 edited
GAATTCGGCACGAGGGCGAGCTGAGTGGTTGTGTGGTCGCGTCTCGGAAACCGGTAGCGC TTGCAGCATGGCTGACCAACTGACTGAAGAGCAGATTGCAGAATTCAAAGAAGCTTTTTC ACTATTTGACAAAGATGGTGATGGAACTATAACAACAAAGGAATTGGGAACTGTAATGAG ATCTCTTGGGCAGAATCCCACAGAAGCAGAGTTACAGGACATGATTAATGAAGTAGATGC TGATGGTAATGGCACAATTGACTTCCCTGAATTTCTGACAATGATGGCAAGAAAAATGAA AGACACAGACAGTGAAGAAGAAATTAGAGAAGCATTCCGTGTGTTTGATAAGGATGGCAA TGGCTATATTAGTGCTGCAGAACTTCGCCATGTGATGACAAACCTTGGAGAGAAGTTAAC AGATGAAGAAGTTGATGAAATGATCAGGGAAGCAGATATTGATGGTGATGGTCAAGTAAA CTATGAAGAGTTTGTACAAATGATGACAGCAAAGTGAAGACCTTGTACAGAATGTGTTAA ATTTCTTGTACAAAATTGTTTATTTGCCTTTTCTTTGTTTGTAACTTATCTGTAAAAGGT TTCTCCCTACTGTCAAAAAAATATGCATGTATAGTAATTAGGACTTCATTCCTCCATGTT TTCTTCCCTTATCTTACTGTCATTGTCCTAAAACCTTATTTTAGAAAATTGATCAAGTAA CATGTTGCATGTGGCTTACTCTGGATATATCTAAGCCCTTCTGCACATCTAAACTTAGAT GGAGTTGGTCAAATGAGGGAACATCTGGGTTATGCCTTTTTTAAAGTAGTTTTCTTTAGG AACTGTCAGCATGTTGTTGTTGAAGTGTGGAGTTGTAACTCTGCGTGGACTATGGACAGT CAACAATATGTACTTAAAAGTTGCACTATTGCAAAACGGGTGTATTATCCAGGTACTCGT ACACTATTTTTTTGTACTGCTGGTCCTGTACCAGAAACATTTTCTTTTATTGTTACTTGC TTTTTAAACTTTGTTTAGCCACTTAAAATCTGCTTATGGCACAATTTGCCTCAAAATCCA TTCCAAGTTGTATATTTGTTTTCCAATAAAAAAATTACAATTTACCCAAAAAAAAAAAAA AAAAACTCGAC >OriGene 5' read for NM_001743 unedited
ATTTTGTAATACGACTTANCTATAGGGCGGCCGCGAATTCGCACGAGGGCGAGCTGATTG GTTGTGTGGTCGCGTCTCGGAAACCGGTAGCGCTTGCAGCATGGCTGACCAACTGACTGA AGAGCAGATTGCAGAATTCAAAGAAGCTTTTTCACTATTTGACAAAGATGGTGATGGAAC TATAACAACAAAGGAATTGGGAACTGTATTTATATCTCTTGGGCAGAATCCCACAGAAGC AGAGTTACAGGACATGATTAATGAAGTAGATGCTGATGGTAATGGCACAATTGACTTCCC TGAATTTCTGACAATGATGGCAAGAAAAATGAAAGACACAGACAGTGAAGAAGAAATTAG AGAAGCATTCCGTGTGTTTGATAAGGATGGCAATGGCTATATTAGTGCTGCAGAACTTCG CCATGTGATGACAAACCTTGGAGAGAAGTTAACAGATGAAGAAGTTGATGAAATGATCAG GGAAGCAGATATTGATGGTGATGGTCAAGTAAACTATGAAGAGTTTGTACAAATGATGAC AGCAAAGTGAAGACCTTGTACAGAATGTGTTAAATTTCTTGTACAAAATTGTTTATTTGC CTTTTCTTTGTTTGTAACTTATCTGTAAAAGGTTTCTCCCTACTGTCAAAAAAATATGCA TGTATAGTAATTAGGACTTCATTCCTCCATGTTTTCTTCCCTTATCTTACTGTCATTGTC CTAAAACCTTATTTTAGAANATTGATCAAGTAACATGTTGCATGTGGCTTACTCTGGATA TATCTAAGCCCTTCTGCACATCTAAACTTAAATGGAGNTGGTCAAATGAGGGAAACATCT GGNTATGCCTTTTTTTAAGTAAGTTTCTTAGGAACTGTCACCATGNTGTTGTTGAAGTGT GGAGTTGAACTCTGCGTGGACTATGGCAGCCACCATATGTACTTAAAAGTGCACTATGCA AACGGTTGATNATCCAGGACTT >OriGene 3' read for NM_001743 unedited
TTTCCCCCCCCCTCCNCCCCTCCNCTTCCCTTACCTTGTAAGCGGCCGCAATCTACATCG AGTTTTTTTTTTTTTTTTTTGGGTAAATTGTAATTTTTTTATTGGAAAACAAATATACAA CTTGCGAAGGATTTTGAGGCAAATTGTGCCATAAGCAGATTTTAAGTGGCTAAACAAAGT TTAAAAAGCAAGTAACAATAAAAGAAAATGTTTCTGGTACAGGACCAGCAGTACAAAAAA ATAGTGTACGAGTACCTGGATAATACACCCGTTTTGCAATAGTGCAACTTTTAAGTACAT ATTGTTGACTGTCCATAGTCCACGCAGAGTTACAACTCCACACTTCAACAACAACATGCT GACAGTTCCTAAAGAAAACTACTTTAAAAAAGGCATAACCCAGATGTTCCCTCATTTGAC CAACTCCATCTAAGTTTAGATGTGCAGAAGGGCTTATATATATCCAGAGTAAGCCACATG CAACATGTTACTTGATCAATTTTCTAAAATAAGGCTTTAGGACAATGACAGCAAGATAAG GGAAGAAAACATGGAGGAATGAAGCCCTAATTACTATACATGCATATTTTTTTGACAGTA GGGAGAAACCTTTTACAGATAAGTTACAAACACAGAAAAGGCAAATAAACAATTTTGTTC CAGAAAATTAACACATTCTGTACAAGTCCTTAACTTTGGTGTCATTATTTTGTACAAACT TTTTATTAGTTTACTTGACCATCACCATTAATATCTGCTTCCCTGATATTTCAATAAACT TTTAATCCGTTAACCTCTCTTCAAGGTTTTGTTATACAATTGCCCAAAGTTCTTTAACCA CTAATAATACCCATTGGCCTTCCCTATTCAAACACACCGGAAAGCCTCCCCTAATTCCTT TCTCAACGGCCTGGGCCTCTTCATTTTTCTTTGCCACTCTTTGCACAGAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001743 |
| Insert Size | 1160 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001743.3, NP_001734.1 |
| RefSeq Size | 1128 bp |
| RefSeq ORF | 450 bp |
| Locus ID | 805 |
| UniProt ID | P62158 |
| Domains | EFh |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Calcium signaling pathway, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Phosphatidylinositol signaling system, Vascular smooth muscle contraction |
| Gene Summary | This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] Transcript Variant: This variant (2) lacks an exon in the 5' coding region, and uses an alternate start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1, and is the same protein encoded by other calmodulin gene family members. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204796 | CALM2 (Myc-DDK-tagged)-Human calmodulin 2 (phosphorylase kinase, delta) (CALM2) |
CNY 1,200.00 |
|
| RC204796L1 | Lenti ORF clone of Human calmodulin 2 (phosphorylase kinase, delta) (CALM2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC204796L2 | Lenti ORF clone of Human calmodulin 2 (phosphorylase kinase, delta) (CALM2), mGFP tagged |
CNY 5,890.00 |
|
| RC204796L3 | Lenti ORF clone of Human calmodulin 2 (phosphorylase kinase, delta) (CALM2), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC204796L4 | Lenti ORF clone of Human calmodulin 2 (phosphorylase kinase, delta) (CALM2), mGFP tagged |
CNY 3,600.00 |
|
| RG204796 | CALM2 (tGFP-tagged) - Human calmodulin 2 (phosphorylase kinase, delta) (CALM2) |
CNY 2,800.00 |
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