EDG2 (LPAR1) (NM_001401) Human Untagged Clone
CAT#: SC119263
LPAR1 (untagged)-Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1
CNY 5,488.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | edg-2; EDG2; Gpcr26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119263 sequence for NM_001401 edited (data generated by NextGen Sequencing)
ATGGCTGCCATCTCTACTTCCATCCCTGTAATTTCACAGCCCCAGTTCACAGCCATGAAT GAACCACAGTGCTTCTACAACGAGTCCATTGCCTTCTTTTATAACCGAAGTGGAAAGCAT CTTGCCACAGAATGGAACACAGTCAGCAAGCTGGTGATGGGACTTGGAATCACTGTTTGT ATCTTCATCATGTTGGCCAACCTATTGGTCATGGTGGCAATCTATGTCAACCGCCGCTTC CATTTTCCTATTTATTACCTAATGGCTAATCTGGCTGCTGCAGACTTCTTTGCTGGGTTG GCCTACTTCTATCTCATGTTCAACACAGGACCCAATACTCGGAGACTGACTGTTAGCACA TGGCTCCTTCGTCAGGGCCTCATTGACACCAGCCTGACGGCATCTGTGGCCAACTTACTG GCTATTGCAATCGAGAGGCACATTACGGTTTTCCGCATGCAGCTCCACACACGGATGAGC AACCGGCGGGTAGTGGTGGTCATTGTGGTCATCTGGACTATGGCCATCGTTATGGGTGCT ATACCCAGTGTGGGCTGGAACTGTATCTGTGATATTGAAAATTGTTCCAACATGGCACCC CTCTACAGTGACTCTTACTTAGTCTTCTGGGCCATTTTCAACTTGGTGACCTTTGTGGTA ATGGTGGTTCTCTATGCTCACATCTTTGGCTATGTTCGCCAGAGGACTATGAGAATGTCT CGGCATAGTTCTGGACCCCGGCGGAATCGGGATACCATGATGAGTCTTCTGAAGACTGTG GTCATTGTGCTTGGGGCCTTTATCATCTGCTGGACTCCTGGATTGGTTTTGTTACTTCTA GACGTGTGCTGTCCACAGTGCGACGTGCTGGCCTATGAGAAATTCTTCCTTCTCCTTGCT GAATTCAACTCTGCCATGAACCCCATCATTTACTCCTACCGCGACAAAGAAATGAGCGCC ACCTTTAGGCAGATCCTCTGCTGCCAGCGCAGTGAGAACCCCACCGGCCCCACAGAAGGC TCAGACCGCTCGGCTTCCTCCCTCAACCACACCATCTTGGCTGGAGTTCACAGCAATGAC CACTCTGTGGTTTAG Clone variation with respect to NM_001401.3 >OriGene 5' read for NM_001401 unedited
GGGTTCACATTTTGTAATACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGCTTC TCCTAGCATGACTTCGATCTGATCAGCAAACAAGAAAATTGTCTCCCGTAGTTCTGGGGC GTGTTCACCACCTACAACCACAGAGCTGTCATGGCTGCCATCTCTACTTCCATCCCTGTA ATTTCACAGCCCCAGTTCACAGCCATGAATGAACCACAGTGCTTCTACAACGAGTCCATT GCCTTCTTTTATAACCGAAGTGGAAAGCATCTTGCCACAGAATGGAACACAGTCAGCAAG CTGGTGATGGGACTTGGAATCACTGTTTGTATCTTCATCATGTTGGCCAACCTATTGGTC ATGGTGGCAATCTATGTCAACCGCCGCTTCCATTTTCCTATTTATTACCTAATGGCTAAT CTGGCTGCTGCAGACTTCTTTGCTGGGTTGGCCTACTTCTATCTCATGTTCAACACAGGA CCCAATACTCGGAGACTGACTGTTAGCACATGGCTCCTTCGTCAGGGCCTCATTGACACC AGCCTGACGGCATCTGTGGCCAACTTACTGGCTATTGCAATCGAGAGGACTTTTACGGGT TTCCGCATGCAGCTCCACACACGGATGAGCAACCGGCGGGTAGTGGTGGTCATTGTGGTC ATCTGGACTATGGCCATCGTTATGGGTGCTATACCCAGTGTGGGCTGGGACTGTATCTGT GATATTGAAAATTGTTCCAACATGGCACCCCTCTACAGTGACTCTTACTTAGTCTTCTGG GCCATTTTCAACTTGGTGACCTTTGTGGAAAGGGGGGGTCTCTATGCTCACACTCTTGGC TATGGTCGCCAGAGAACATGAGAATGTCTCGGATAATTCTGGACCCCGCCCATCGGGAAA CATGC >OriGene 3' read for NM_001401 unedited
CGGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGATATGACAATCCTTTATTC ACTCGGCACATTTGGTTTCTTTGCATTTTCTTCCATTTTACATTGCAGGTGTGGCTACCA AGAGCTGGATAACGAGTCCCTCAAACAAAGTTTGGAATTGCGAGATATATTGGGGTACCT TGATTCTTGAGACAGTTGAATTCTTCTAGTTGATCTTGTTGTATTAAAAAGTCACTCTCA ACTGAAGTGACCACTGCATTTCTTTTGTAAAAAGGTCATTTGACTGGCTTTTCCTCACAA CTGCCACCCATGCAGTACAAAAGCAGGAAATCCCTTTGCATGAAAGGTGTAAGTACAAGA TGACATTTCACATTTTTTTAAAAAAAGAATCCTTCATGGGAATATATCCTAATAATCAAT TATATGGAGACAGTTTTATGTACACCAAATTTCTGCAACTTTATAATAATCAAAATTAGA AACAACCTAAATAGTTAACAACATGGGAATGGTTAAATAAACTGAGTTGCATCCATTAAA TGGAATATAATATAGCCATTAAAATTATGTTTTTGTAAAATTTTTAATGCCATAAGAAAA TGTGGCAATTTTGCAATGAAAAAGATCTACTTATAAAACTGTTTACAGTATGACTCCAAT TATGTAAAAAAAGTATACAATACACATATAGGCCTACATGGGGGTTGCTTTTTAAGGAGG CTACTTCTGGGTTGCGATATTATAGAAATATTTTGCCTTTTATACATTNCGTATTTTTCA AGTTTCTTGATGAGTTATTATTTTCAAAGACTACCAATTTTCCTCTGAATACTGGAATTA AATGTACCTGGGATTTTTAATTATGGGAACAACTTTAGGCTTCTCTTCTTGACTTTTAGA TAACTACACTTGGGATAAACTCCTTCCTGTTTAACTGGTC |
Restriction Sites | NotI-NotI |
ACCN | NM_001401 |
Insert Size | 2910 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001401.3, NP_001392.2 |
RefSeq Size | 3104 bp |
RefSeq ORF | 1095 bp |
Locus ID | 1902 |
UniProt ID | Q92633 |
Domains | 7tm_1 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Gap junction, Neuroactive ligand-receptor interaction |
Gene Summary | The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020] Transcript Variant: This variant (1) represents the shorter transcript. Variants 1-26 encode the same protein. |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206065 | LPAR1 (Myc-DDK-tagged)-Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1 |
CNY 5,488.00 |
|
RC206065L1 | Lenti ORF clone of Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
RC206065L2 | Lenti ORF clone of Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC206065L3 | Lenti ORF clone of Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC206065L4 | Lenti ORF clone of Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
RG206065 | LPAR1 (tGFP-tagged) - Human lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1 |
CNY 7,088.00 |