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ELAVL1 (NM_001419) Human Untagged Clone
CAT＃: SC119271
ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1)
CNY 2,400.00
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ELAV1; Hua; HUR; MelG |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119271 sequence for NM_001419 edited (data generated by NextGen Sequencing)
ATGTCTAATGGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACG AATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGATGAGTTACGAAGCCTGTTC AGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGC TTGGGCTATGGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACG CTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCGTATGCTCGCCCGAGCTCA GAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAG GACGTAGAAGACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGAT CAGACTACAGGTTTGTCCAGAGGGGTTGCGTTTATCCGGTTTGACAAACGGTCGGAGGCA GAAGAGGCAATTACCAGTTTCAATGGTCATAAACCCCCAGGTTCCTCTGAGCCCATCACA GTGAAGTTTGCAGCCAACCCCAACCAGAACAAAAACGTGGCACTCCTCTCGCAGCTGTAC CACTCGCCAGCGCGACGGTTCGGAGGCCCCGTTCACCACCAGGCGCAGAGATTCAGGTTC TCCCCCATGGGCGTCGATCACATGAGCGGGCTCTCTGGCGTCAACGTGCCAGGAAACGCC TCCTCCGGCTGGTGCATTTTCATCTACAACCTGGGGCAGGATGCCGACGAGGGGATCCTC TGGCAGATGTTTGGGCCGTTTGGTGCCGTCACCAATGTGAAAGTGATCCGCGACTTCAAC ACCAACAAGTGCAAAGGGTTTGGCTTTGTGACCATGACAAACTATGAAGAAGCCGCGATG GCCATAGCCAGCCTGAACGGCTACCGCCTGGGGGACAAAATCTTACAGGTTTCCTTCAAA ACCAACAAGTCCCACAAATAA Clone variation with respect to NM_001419.2 >OriGene 5' read for NM_001419 unedited
GGTGCAGATTTTGTATACATTCACTATAGGCGGCCGCGNAATTCGCACGAGGCGCCACCG CCGCCACCGCTACCGAGGCCGAGCGGAGCCGTTAGCGCCGCGCCGCCGCCGCCTCCCGCC CGCCCCGGAGCAGCCCCGGGCCCGCCCGCCCGCATCCAGATTTTTGAAAAATACAATGTC TAATGGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACGAATTT GATCGTCAACTACCTCCCTCAGAACATGACCCAGGATGAGTTACGAAGCCTGTTCAGCAG CATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGG CTATGGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACGCTGAA CGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCGTATGCTCGCCCGAGCTCAGAGGT GATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAGGACGT AGAAGACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGATCAGAC TACAGGTTTGTCCAGAGGGGTTGCGTTTATTCGGTTTGACAAACGGTCCGAGGCAGAAGA GGCCATTACCAGTTTCAATGGTCATAAACCCCCCAGTTCCTTTGAGCCCATTACAGTGAA GTTTGCAGCCAACCCCAACCAGTACATAAACGTTGCATTCCTCTTGAAGTTGTCCACTTG CCAGGCGACGGTTCTGAGGCCCCGTTCACCACCAGCGCAAAATTTATGTTCTTCCCCATG GGCGCTCGTTACATTAGCGGGCTTCTTGGGTTAACGGGCCAGGAAACGCCTCCTCCGGTG GTGCATTTTATTCTCAACTGGGGCAGGAGCC >OriGene 3' read for NM_001419 unedited
TATTCTATGNACCGCGNCCGCATTCTNANGATCGNATTTTTTTTTTTTTTTTTTCGAGCA AAACAAAATCAAATTTAATGGTCTTAAATGCAAAAGTAAAAACAAACAAAAAACACAAAA AAGCAAAAAAAAATTAACAGAACAGAACAACCCAAAATGTCAAGGCAGTTATGAAGAGAA CTTTGAGGGTTAATCTTTAAAACTACAAATCAAAGGTTTTGGTTAATAGATAACTGGCAA GAAGTAAGTACTTTTCTGCTGAGTGTTCATACAAAAGCAAAATTCCAAAACAAAATCCGA CTAAAATAGAAAAAGGTCTAAGCGCTCACGAGAAGGGATGCGAGAAATACAATGCTCAAA TGTTTCTGTGTTATTAAAATACAGAGCCATTTTACGCCTCCAAGCTATGTTAAATGCTCT GGAAAACGGGAGAAATTATCGTGAACAACAGTATCCAATGTGTGGGGCGCTGTGCATGCA ATGTGTGGACAGAAACTCGGGATGTCAGAGTAGCAACACATCTTCAGGCGTGCCTGGAGC TTAGATCTGACTCTGGAATATACTGGAGTTTCCCTGAAACTCTTTGGTCCATTCCCATTG GTGCCTGGGCTTACGAAACACGTTTGTGTCCTTTCTGGGAAGGGGCCCGCCCAGCATGCC ACCCCGTGGCCCCCGGGCCCCAGTGGTGGGCCCACGCTGGAAGGGCCCCGCCGCCATTCC CAGAACCACCTCGGAAAAACCCGGACTGAGTGAACAGGAAGGGGCCAACGGGCCCTGCCT GGAAAAGGAACTTTCTGTCAAACAAAGCAAACATGGTTAAAATGTTGAAACGGTTGGAAA AAACCACACCCCCCATTTGGTTAAACTCTTTTGTTAAAAACTAAAACTAAAGGGGGTTTT TTTGCCTCCCCATCTTGGGGAAAAATGAAAGAAAACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001419 |
| Insert Size | 2250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001419.2, NP_001410.2 |
| RefSeq Size | 6075 bp |
| RefSeq ORF | 981 bp |
| Locus ID | 1994 |
| UniProt ID | Q15717 |
| Domains | RRM |
| Gene Summary | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
,null,
Oncotarget
,PubMed ID 26314962
[ELAVL1]
|
|
The mRNA-stabilizing Factor HuR Protein Is Targeted by ?-TrCP Protein for Degradation in Response to Glycolysis Inhibition *
,null,
The Journal of Biological Chemistry
,PubMed ID 23115237
[ELAVL1]
|
|
The mRNA-stabilizing Factor HuR Protein Is Targeted by ß-TrCP Protein for Degradation in Response to Glycolysis Inhibition
,Po-Chen Chu, Hsiao-Ching Chuang, Samuel K. Kulp, and Ching-Shih Chen,
J. Biol. Chem., Dec 2012; 287: 43639 - 43650.
[ELAVL1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201562 | ELAVL1 (Myc-DDK-tagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 2,400.00 |
|
| RC201562L1 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201562L2 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged |
CNY 5,890.00 |
|
| RC201562L3 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201562L4 | Lenti ORF clone of Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mGFP tagged |
CNY 4,800.00 |
|
| RG201562 | ELAVL1 (tGFP-tagged) - Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 4,000.00 |
|
| SC322158 | ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1) |
CNY 2,400.00 |
