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GUCY1B1 (NM_000857) Human Untagged Clone
CAT＃: SC119659
GUCY1B3 (untagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3)
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119659 sequence for NM_000857 edited (data generated by NextGen Sequencing)
ATGTACGGATTTGTGAATCACGCCCTGGAGTTGCTGGTGATCCGCAATTACGGCCCCGAG GTGTGGGAAGACATCAAAAAAGAGGCACAGTTAGATGAAGAAGGACAGTTTCTTGTCAGA ATAATATATGATGACTCCAAAACTTATGATTTGGTTGCTGCTGCAAGCAAAGTCCTCAAT CTCAATGCTGGAGAAATCCTCCAAATGTTTGGGAAGATGTTTTTCGTCTTTTGCCAAGAA TCTGGTTATGATACAATCTTGCGTGTCCTGGGCTCTAATGTCAGAGAATTTCTACAGAAC CTTGATGCTCTGCACGACCACCTTGCTACCATCTACCCAGGAATGCGTGCACCTTCCTTT AGGTGCACTGATGCAGAAAAGGGCAAAGGACTCATTTTGCACTACTACTCAGAGAGAGAA GGACTTCAGGATATTGTCATTGGAATCATCAAAACAGTGGCACAACAAATCCATGGCACT GAAATAGACATGAAGGTTATTCAGCAAAGAAATGAAGAATGTGATCATACTCAATTTTTA ATTGAAGAAAAAGAGTCAAAAGAAGAGGATTTTTATGAAGATCTTGACAGATTTGAAGAA AATGGTACCCAGGAATCACGCATCAGCCCATATACATTCTGCAAAGCTTTTCCTTTTCAT ATAATATTTGACCGGGACCTAGTGGTCACTCAGTGTGGCAATGCTATATACAGAGTTCTC CCCCAGCTCCAGCCTGGGAATTGCAGCCTTCTGTCTGTCTTCTCGCTGGTTCGTCCTCAT ATTGATATTAGTTTCCATGGGATCCTTTCTCACATCAATACTGTTTTTGTATTGAGAAGC AAGGAAGGATTGTTGGATGTGGAGAAATTAGAATGTGAGGATGAACTGACTGGGACTGAG ATCAGCTGCTTACGTCTCAAGGGTCAAATGATCTACTTACCTGAAGCAGATAGCATACTT TTTCTATGTTCACCAAGTGTCATGAACCTGGACGATTTGACAAGGAGAGGGCTGTATCTA AGTGACATCCCTCTGCATGATGCCACGCGCGATCTTGTTCTTTTGGGAGAACAATTTAGA GAGGAATACAAACTCACCCAAGAACTGGAAATCCTCACTGACAGGCTACAGCTCACGTTA AGAGCCCTGGAAGATGAAAAGAAAAAGACAGACACATTGCTGTATTCTGTCCTTCCTCCG TCTGTTGCCAATGAGCTGCGGCACAAGCGTCCAGTGCCTGCCAAAAGATATGACAATGTG ACCATCCTCTTTAGTGGCATTGTGGGCTTCAATGCTTTCTGTAGCAAGCATGCATCTGGA GAAGGAGCCATGAAGATCGTCAACCTCCTCAACGACCTCTACACCAGATTTGACACACTG ACTGATTCCCGGAAAAACCCATTTGTTTATAAGGTGGAGACTGTTGGTGACAAGTATATG ACAGTGAGTGGTTTACCAGAGCCATGCATTCACCATGCACGATCCATCTGCCACCTGGCC TTGGACATGATGGAAATTGCTGGCCAGGTTCAAGTAGATGGTGAATCTGTTCAGATAACA ATAGGGATACACACTGGAGAGGTAGTTACAGGTGTCATAGGACAGCGGATGCCTCGATAC TGTCTTTTTGGGAATACTGTCAACCTCACAAGCCGAACAGAAACCACAGGAGAAAAGGGA AAAATAAATGTGTCTGAATATACATACAGATGTCTTATGTCTCCAGAAAATTCAGATCCA CAATTCCACTTGGAGCACAGAGGCCCAGTGTCCATGAAGGGCAAAAAAGAACCAATGCAA GTTTGGTTTCTATCCAGAAAAAATACAGGAACAGAGGAAACAAAGCAGGATGATGACTGA Clone variation with respect to NM_000857.2 >OriGene 5' read for NM_000857 unedited
GCGGTCAAATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGCCGCTG CCGCCTCTGCCTGGGTCCCTTCGGCCGTACCTCTGCGTGGGGGCTGCCTCCCCGGCTCCC GGTGCAGACACCATGTACGGATTTGTGAATCACGCCCTGGAGTTGCTGGTGATCCGCAAT TACGGCCCCGAGGTGTGGGAAGACATCAAAAAAGAGGCACAGTTAGATGAAGAAGGACAG TTTCTTGTCAGAATAATATATGATGACTCCAAAACTTATGATTTGGTTGCTGCTGCAAGC AAAGTCCTCAATCTCAATGCTGGAGAAATCCTCCAAATGTTTGGGAAGATGTTTTTCGTC TTTTGCCAAGAATCTGGTTATGATACAATCTTGCGTGTCCTGGGCTCTAATGTCAGAGAA TTTCTACAGAACCTTGATGCTCTGCACGACCACCTTGCTACCATCTACCCAGGAATGCGT GCACCTTCCTTTAGGTGCACTGATGCAGAAAAGGGCAAAGGACTCATTTTGCACTACTAC TCANGAGAGAGAGGACTTCAGGATATTGTCATTGGAATCATCAAAACAGTGGCACAACAA ATCCATGGCACTGAAATAGACATGAAGGTTATTCAGCANAGAAATGAAAGATGTGATCAT ACTCAATTTTTAAATTGAGAAAAGAGTCAAAAGAGAGGATTTTATGAAGATCTTGACAGA TTTGAAGAAATGGTACCCAGGAATCACGCATCAGCCCATATACATTCTGCNAAAGCTTTN NCCTTTCATATATATTTGACCGGGNACCTAGTGGTCACTCAGTGTGGCAATGCTATATAC AAAGTTCTCCCCAGCTCCAGCCTGGGGATTGCANGCTTCTGGCTGGCTTCTCGCTGGGTC GNCCTCATATTGAATTAGGTTCCAGGGGATCCTTTTT >OriGene 3' read for NM_000857 unedited
AGCTATGGACCGGCGGCCGCAATCTAGNAGTCGGTTTTTTTTTTTTTTTTTTTTTTTGAA AAAAAAATTTATTACAGACTCTTTTACACATTAACATGGAACATTTATACATATATCGAT GTGCTGATATGAAATACTAAATTTAAAGGCAAACATTTTTACACAAAAGTAGTTGCACTC TATTTTATAAAGATAGATATTAATAAGTTATCAGAGACATTTAAGAGCTAGAGGCCAATT ATTCCAACAGTAATGCATTCTATGCTGAAAGTAAACTAAGTTTTCTGAACATGATGTCCT GGATATAATCACATTCTTCTAAGCTAAGGAAAGGGAGCTCATTTCTGGGAATACAAGGCC AAGAAGGGCTCTAACAGCAGTATCCCAGCAGTGTGTTTCCAGATTTATTCTTGGATGTGG TTGGAGCTCCCAACATTTAGCCTGAACTAATGTAACAGCTCAATGTGAAACAATGCAGCT TTCTGTAACAGCTGCCTGTGGTTAATGAGATTTAATACAGGGGATACAGTTACAAATGAT AGCATTTTAGAAGAATTATAATTGCCATATGATTTGAATTAGTAATCAAATACTTTAATA ACAGAAACGTGTATTCTATATTTCTGAAAGGGAAGTAGCATACTTCAAAATAGTCACTAT TTTCTTAGCATGATATGTTAATTCTTACTTTGGGAGTCTGAAAATAATTGCATTTTTTCC CCTAAAACTTAGAATTCACTCCTTTAGAAATGATTTCTATAATGATATACACCAACATGA TATAAACTTTATTACATTATAGNCATTAAAATATACATATACATATATGTGGGAACACTA ACAGATTNGGNTAACATGNATATAATATACACATGGGNCCAACACTGGTNCAGNTNCATT TAACTAAAAATCACAATATTTATTGGGTGCCTACTACTTGCAGACACCAGGTTAGGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000857 |
| Insert Size | 2930 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000857.1, NP_000848.1 |
| RefSeq Size | 2443 bp |
| RefSeq ORF | 1860 bp |
| Locus ID | 2983 |
| UniProt ID | Q02153 |
| Domains | CYCc |
| Protein Families | Druggable Genome |
| Protein Pathways | Gap junction, Long-term depression, Purine metabolism, Vascular smooth muscle contraction |
| Gene Summary | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter than isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208205 | GUCY1B3 (Myc-DDK-tagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 3,990.00 |
|
| RC208205L1 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208205L2 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), mGFP tagged |
CNY 5,890.00 |
|
| RC208205L3 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208205L4 | Lenti ORF clone of Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3), mGFP tagged |
CNY 5,890.00 |
|
| RG208205 | GUCY1B3 (tGFP-tagged) - Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 4,370.00 |
|
| SC322151 | GUCY1B3 (untagged)-Human guanylate cyclase 1, soluble, beta 3 (GUCY1B3) |
CNY 2,950.00 |
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