CD4 (NM_000616) Human Untagged Clone

CAT#: SC119790

CD4 (untagged)-Human CD4 molecule (CD4), transcript variant 1



  "NM_000616" in other vectors (6)

CNY 3,656.00


货期*
现货

规格
    • 10 ug

Cited in 2 publications.

Product images

经常一起买 (4)
CD4 mouse monoclonal antibody, clone OTI5D9 (formerly 5D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CD4mut; IMD79; OKT4D
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000616 edited
GAATTCGGCACGAGGCAGAGCTCCAAGTCCTCACACAGATACGCCTGTTTGAGAAGCAGC
GGGCAAGAAAGACGCAAGCCCAGAGGCCCTGCCATTTCTGTGGGCTCAGGTCCCTACTGG
CTCAGGCCCCTGCCTCCCTCGGCAAGGCCACAATGAACCGGGGAGTCCCTTTTAGGCACT
TGCTTCTGGTGCTGCAACTGGCGCTCCTCCCAGCAGCCACTCAGGGAAAGAAAGTGGTGC
TGGGCAAAAAAGGGGATACAGTGGAACTGACCTGTACAGCTTCCCAGAAGAAGAGCATAC
AATTCCACTGGAAAAACTCCAACCAGATAAAGATTCTGGGAAATCAGGGCTTCTTCTTAA
CTAAAGGTCCATCCAAGCTGAATGATCGCGCTGACTCAAGAAGAAGCCTTTGGGACCAAG
GAAACTTTCCCCTGATCATCAAGAATCTTAAGATAGAAGACTCAGATACTTACATCTGTG
AAGTGGAGGACCAGAAGGAGGAGGTGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTG
ACACCCACCTGCTTCAGGGGCAGAGCCTGACCCTGACCTTGGAGAGCCCCCCTGGTAGTA
GCCCCTCAGTGCAATGTAGGAGTCCAAGGGGTAAAAACATACAGGGGGGGAAGACCCTCT
CCGTGTCTCAGCTGGAGCTCCAGGATAGTGGCACCTGGACATGCACTGTCTTGCAGAACC
AGAAGAAGGTGGAGTTCAAAATAGACATCGTGGTGCTAGCTTTCCAGAAGGCCTCCAGCA
TAGTCTATAAGAAAGAGGGGGAACAGGTGGAGTTCTCCTTCCCACTCGCCTTTACAGTTG
AAAAGCTGACGGGCAGTGGCGAGCTGTGGTGGCAGGCGGAGAGGGCTTCCTCCTCCAAGT
CTTGGATCACCTTTGACCTGAAGAACAAGGAAGTGTCTGTAAAACGGGTTACCCAGGACC
CTAAGCTCCAGATGGGCAAGAAGCTCCCGCTCCACCTCACCCTGCCCCAGGCCTTGCCTC
AGTATGCTGGCTCTGGAAACCTCACCCTGGCCCTTGAAGCGAAAACAGGAAAGTTGCATC
AGGAAGTGAACCTGGTGGTGATGAGAGCCACTCAGCTCCAGAAAAATTTGACCTGTGAGG
TGTGGGGACCCACCTCCCCTAAGCTGATGCTGAGTTTGAAACTGGAGAACAAGGAGGCAA
AGGTCTCGAAGCGGGAGAAGGCGGTGTGGGTGCTGAACCCTGAGGCGGGGATGTGGCAGT
GTCTGCTGAGTGACTCGGGACAGGTCCTGCTGGAATCCAACATCAAGGTTCTGCCCACAT
GGTCCACCCCGGTGCAGCCAATGGCCCTGATTGTGCTGGGGGGCGTCGCCGGCCTCCTGC
TTTTCATTGGGCTAGGCATCTTCTTCTGTGTCAGGTGCCGGCACCGAAGGCGCCAAGCAG
AGCGGATGTCTCAGATCAAGAGACTCCTCAGTGAGAAGAAGACCTGCCAGTGTCCTCACC
GGTTTCAGAAGACATGTAGCCCCATTTGAGGCACGAGGCCAGGCAGATCCCACTTGCAGC
CTCCCCAGGTGTCTGCCCCGCGTTTCCTGCCTGCGGACCAGATGAATGTAGCAGATCCCA
GGCCTCTGGCCTCCTGTTCGCCTCCTCTACAATTTGCCATTGTTTCTCCTGGGTTAGGCC
CCGGCTTCACTGGTTGAGTGTTGCTCTCTAGTTTCCAGAGGCTTAATCACACCGTCCTCC
ACGCCATTTCCTTTTCCTTCAAGCCTAGCCCTTCTCTCATCATTTCTCTCTGACCCTCTC
CCCACTGCTCATTTGGATCCCAGGGGAGTGTTCAGGGCCAGCCCTGGCTGGCATGGAGGG
TGAGGCTGGGTGTCTGGAAGCATGGAGCATGGGACTGTTCTTTTACAAGACAGGACCCTG
GGACCACAGAGGGCAGGAACTTGCACAAAATCACACAGCCAAGCCAGTCAAGGATGGATG
CAGATCCAGAGGTTTCTGGCAGCCAGTACCTCCTGCCCCATGCTGCCCGCTTCTCACCCT
ATGTGGGTGGGGCCACAGACTCACATCCTGACCTTGCACAAACAGCCCCTCTGGACACAG
CCCCATGTACACGGCCTCAAGGGATGTCTCACATCCTCTGTCTATTTGAGACTTAGAAAA
ATCCTACAAGGCTGGCAGTGACAGAACTAAGATGATCATCTCCAGTTTATAGACCAGAAC
CAGAGCTCAGAGAGGCTAGATGATTGATTACCAAGTGCCGGACTAGCAAGTGCTGGAGTC
GGGACTAACCCAGGTCCCTTGTCCCAAGTTCCACTGCTGCCTCTTGAATGCAGGGACAAA
TGCCACACGGCTCTCACCAGTGGCTAGTGGTGGGTACTCAATGTGTACTTTTGGGTTCAC
AGAAGCACAGCACCCATGGGAAGGGTCCATCTCAGAGAATTTACGAGCAGGGATGAAGGC
CTCCCTGTCTAAAATCCCTCCTTCATCCCCCGCTGGTGGCAGAATCTGTTACCAGAGGAC
AAAGCCTTTGGCTCTTCTAATCAGAGCGCAAGCTGGGAGCACAGGCACTGCAGGAGAGAA
TGCCCAGTGACCAGTCACTGACCCTGTGCAGAACCTCCTGGAAGCGAGCTTTGCTGGGAG
AGGGGGTAGCTAGCCTGAGAGGGAACCCTCTAAGGGACCTCAAAGGTGATTGTGCCAGGC
TCTGCGCCTGCCCCACACCCTCCCTTACCCTCCTCCAGACCATTCAGGACACAGGGAAAT
CAGGGTTACAAATCTTCTTGATCCACTTCTCTCAGGATCCCCTCTCTTCCTACCCTTCCT
CACCACTTCCCTCAGTCCCAACTCCTTTTCCCTATTTCCTTCTCCTCCTGTCTTTAAAGC
CTGCCTCTTCCAGGAAGACCCCCCTATTGCTGCTGGGGCTCCCCATTTGCTTACTTTGCA
TTTGTGCCCACTCTCCACCCCTGCTCCCCTGAGCTGAAATAAAAATACAATAAACTTACT
ATAAAGATGAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_000616 unedited
GGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGCAGAGCTCC
AAGTCCTCACACAGATACGCCTGTTTGAGAAGCAGCGGGCAAGAAAGACGCAAGCCCAGA
GGCCCTGCCATTTCTGTGGGCTCAGGTCCCTACTGGCTCAGGCCCCTGCCTCCCTCGGCA
AGGCCACAATGAACCGGGGAGTCCCTTTTAGGCACTTGCTTCTGGTGCTGCAACTGGCGC
TCCTCCCAGCAGCCACTCAGGGAAAGAAAGTGGTGCTGGGCAAAAAAGGGGATACAGTGG
AACTGACCTGTACAGCTTCCCAGAAGAAGAGCATACAATTCCACTGGAAAAACTCCAACC
AGATAAAGATTCTGGGAAATCAGGGCTTCTTCTTAACTAAAGGTCCATCCAAGCTGAATG
ATCGCGCTGACTCAAGAAGAAGCCTTTGGGACCAAGGAAACTTTCCCCTGATCATCAAGA
ATCTTAAGATAGAAGACTCAGATACTTACATCTGTGAAGTGGAGGACCAGAAGGAGGAGG
TGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTGACACCCACCTGCTTCAGGGGCAGA
GCCTGACCCTGACCTTGGAGAGCCCCCCTGGTAGTAGCCCCTCAGTGCAATGTAGGAGTC
CAAGGGGTAAAAACATACAGGGGGGGAAGACCCTCTCCGTGTCTCAGCTGGAGCTCCAGG
ATAGTGGCACCTGGACATGCACTGTCTTGCAGAACCAGAAGAAAGTGGAGTTCAAAATAG
ACATCGTGGTGCTAGCTNTCCAGAAGCCTNCAGCATAGTCTATAAGAAAGAAGGGGACAG
GTGGAGTTCTCCTTCCACTCGCCTTTACCAGTGAAAGCTGACGGGCANTGGCGAACTGTG
GTGGCANGGCGGAAC
>OriGene 3' read for NM_000616 unedited
CGCTTTTAAAGTGAGTTTTTTTTTTTTTTTTTTAATCTTTATAGAAAGTTTATTGTATTT
TTATTTCAGCTCAGGGGAGCAGGGGTGGAGAGTGGGCACAAATGCAAAGTAAGCAAATGG
GGAGCCCCAGCAGCAATAGGGGGGTCTTCCTGGAAGAGGCAGGCTTTAAAGACAGGAGGA
GAAGGAAATAGGGAAAAGGAGTTGGGACTGAGGGAAGTGGTGAGGAAGGGTAGGAAGAGA
GGGGATCCTGAGAGAAGTGGATCAAGAAGATTTGTAACCCTGATTTCCCTGTGTCCTGAA
TGGTCTGGAGGAGGGTAAGGGAGGGTGTGGGGCAGGCGCATAGCCTGGCACAATCACCTT
TGAGGTCCCTTAGAGGGTTCCCTCTCAGGCTAGCTACCCCCTCTCCCAGCAAAGCTCGCT
TCCAGGAGGTTCTGCACAGGGTCAGTGACTGGTCACTGGGCATTCTCTCCTGCAGTGCCT
GTGCTCCCAGCTTGCGCTCTGATTATAAGAGCCAAAGGCTTTGACCTCTGGTAACAGATT
CTGCCACCAGCGGGGGATGAAGGAGGGATTTTAGACAGGGAGGCCTTCATCCCTGCTCGA
AAATTCTCTGAGATGGACCCTTCCCATGGGTGCTGTGCTTCTGTGAACCCATAAGCACAC
ATTGAGTACCCCACCACTACCCACTGGTGAGAGCCGTGCGGCATTTGACCCTGCCTTCAA
GAAGCAATAGTGGAACTTGGGACAAGGACCTGGGTTACCTCCGACTCAACACCTTGCTAT
ACGGCCCTCGCGCATAATCTTTTACCTCTCTAGCCTCTGCTCCGCATTTTTCCCGCGCAG
TCTCCCCTCCCTCCTTGCCCTCCCTTTTCTCACCCACCTTCTATTTTCCTCCTCCCCTCT
CGTCTCCCTCGACCTTTTCCTTCTCTCTCCCATCTTCTCCCTCCTCCCCCCCTCCCCCCT
CCCCCTCGTCTCTCCCTTCCAT
Restriction Sites NotI-NotI     
ACCN NM_000616
Insert Size 3070 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000616.2, NP_000607.1
RefSeq Size 3084 bp
RefSeq ORF 1377 bp
Locus ID 920
UniProt ID P01730
Domains ig, IGv, IGc2, IG
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
Gene Summary This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Transcript Variant: This variant (1) encodes the longest isoform (1) including a signal peptide and a mature peptide. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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