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MC2 receptor (MC2R) (NM_000529) Human Untagged Clone
CAT＃: SC119819
MC2R (untagged)-Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACTHR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000529, RT-PCR generated
ATGAAGCACATTATCAACTCGTATGAAAACATCAACAACACAGCAAGAAATAATTCCGAC TGTCCTCGTGTGGTTTTGCCGGAGGAGATATTTTTCACAATTTCCATTGTTGGAGTTTTG GAGAATCTGATCGTCCTGCTGGCTGTGTTCAAGAATAAGAATCTCCAGGCACCCATGTAC TTTTTCATCTGTAGCTTGGCCATATCTGATATGCTGGGCAGCCTATATAAGATCTTGGAA AATATCCTGATCATATTGAGAAACATGGGCTATCTCAAGCCACGTGGCAGTTTTGAAACC ACAGCCGATGACATCATCGACTCCCTGTTTGTCCTCTCCCTGCTTGGCTCCATCTTCAGC CTGTCTGTGATTGCTGCGGACCGCTACATCACCATCTTCCACGCACTGCGGTACCACAGC ATCGTGACCATGCGCCGCACTGTGGTGGTGCTTACGGTCATCTGGACGTTCTGCACGGGG ACTGGCATCACCATGGTGATCTTCTCCCATCATGTGCCCACAGTGATCACCTTCACGTCG CTGTTCCCGCTGATGCTGGTCTTCATCCTGTGCCTCTATGTGCACATGTTCCTGCTGGCT CGATCCCACACCAGGAAGATCTCCACCCTCCCCAGAGCCAACATGAAAGGGGCCATCACA CTGACCATCCTGCTCGGGGTCTTCATCTTCTGCTGGGCCCCCTTTGTGCTTCATGTCCTC TTGATGACATTCTGCCCAAGTAACCCCTACTGCGCCTGCTACATGTCTCTCTTCCAGGTG AACGGCATGTTGATCATGTGCAATGCCGTCATTGACCCCTTCATATATGCCTTCCGGAGC CCAGAGCTCAGGGACGCATTCAAAAAGATGATCTTCTGCAGCAGGTACTGGTAG >OriGene 5' read for NM_000529 unedited
GGGGGACTTCGGTATTGTAACAGAATCCACGGTAGGCGGAACGCCATGTGATGGGTATCT GCAGATTTCGGCTTAAATGAAGCACATTATCAACTCGTATGTAAAACATCAACAACACAG CAAGAAATAATTCCGACTGTCCTCGTGTGGTTTTGCCGGAGGAGATATTTTTCACAATTT CCATTGTTGGAGTTTTGGAGAATCTGATCGTCCTGTTTTCTGTGTTCAAGAATAAGAATC TCCAGGCACCCATGTACTTTTTCATCTGTAGCTTGGCCATATCTGATATGCTGGGCAGCC TATATAAGATCTTGGAAAATATCCTGATCATATTGAGAAACATGGGCTATCTCAAGCCAC GTGGCAGTTTTGAAACCACAGCCGATGACATCATCGACTCCCTGTTTGTCCTCTCCCTGC TTGGCTCCATCTTCAGCCTGTCTGTGATTGCTGCGGACCGCTACATCACCATCTTCCACG CACTGCGGTACCACAGCATCGTGACCATGCGCCGCACTGTGGTGGTGCTTACGGTCATCT GGACGTTCTGCACGGGGACTGGCATCACCATGGTGATCTTCTCCCATCATGTGCCCACAG TGATCACCTTCACGTCGCTGTTCCCGCTGATGCTGGTCTTCATCCTGTGCCTCTATGTGC ACATGTTCCTGCTGGCTCGATCCCACACCAGGAAGATCTCCACCCTCCCCAGACCAACAT GAAAGGGGCCATCACACTGACCATCCTGCTCGGGGTTCTTCATCTTCTGCTGGGCCCCCC TTGTGCTTTATGTCCTCTTGATGACATTCTGCCCAAGTAACCCCTACTGCGCCTGCTCAT GTCTTTCTTCCGGTGAAACGGCTGTTGATCT |
| Restriction Sites | Please inquire |
| ACCN | NM_000529 |
| Insert Size | 1000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000529.2, NP_000520.1 |
| RefSeq Size | 3652 bp |
| RefSeq ORF | 894 bp |
| Locus ID | 4158 |
| UniProt ID | Q01718 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014] Transcript Variant: This variant (1) and variant 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Regulation of G Protein–Coupled Receptor Signaling: Specific Dominant-Negative Effects of Melanocortin 2 Receptor Accessory Protein 2
,Julien A. Sebag and Patricia M. Hinkle,
Sci. Signal., Apr 2010; 3: ra28
[MC2R]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210483 | MC2R (Myc-DDK-tagged)-Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R) |
CNY 3,600.00 |
|
| RC210483L1 | Lenti ORF clone of Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC210483L2 | Lenti ORF clone of Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), mGFP tagged |
CNY 6,000.00 |
|
| RC210483L3 | Lenti ORF clone of Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210483L4 | Lenti ORF clone of Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R), mGFP tagged |
CNY 5,890.00 |
|
| RG210483 | MC2R (tGFP-tagged) - Human melanocortin 2 receptor (adrenocorticotropic hormone) (MC2R) |
CNY 5,200.00 |
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