United States
Germany
Japan
United Kingdom
China
PON1 (NM_000446) Human Untagged Clone
CAT＃: SC119866
PON1 (untagged)-Human paraoxonase 1 (PON1)
CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ESA; MVCD5; PON |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000446 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000446.3, NP_000437.3 |
| RefSeq Size | 2395 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 5444 |
| UniProt ID | P27169 |
| Domains | Arylesterase |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Metabolic pathways |
| Gene Summary | This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Chimeric Proteins Combining Phosphatase and Cellulose-Binding Activities: Proof-of-Concept and Application in the Hydrolysis of Paraoxon
,Goncalves, LM;Chaimovich, H;Cuccovia, IM;Marana, SR;,
Protein Pept. Lett.
,PubMed ID 24555432
[PON1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210356 | PON1 (Myc-DDK-tagged)-Human paraoxonase 1 (PON1) |
CNY 3,656.00 |
|
| RC210356L1 | Lenti ORF clone of Human paraoxonase 1 (PON1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210356L2 | Lenti ORF clone of Human paraoxonase 1 (PON1), mGFP tagged |
CNY 5,890.00 |
|
| RC210356L3 | Lenti ORF clone of Human paraoxonase 1 (PON1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210356L4 | Lenti ORF clone of Human paraoxonase 1 (PON1), mGFP tagged |
CNY 5,890.00 |
|
| RG210356 | PON1 (tGFP-tagged) - Human paraoxonase 1 (PON1) |
CNY 5,256.00 |
