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PON2 (NM_000305) Human Untagged Clone
CAT＃: SC119958
PON2 (untagged)-Human paraoxonase 2 (PON2), transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119958 sequence for NM_000305 edited (data generated by NextGen Sequencing)
ATGGGGCGGCTGGTGGCTGTGGGCTTGCTGGGGATCGCGCTGGCGCTCCTGGGCGAGAGG CTTCTGGCACTCAGAAATCGACTTAAAGCCTCCAGAGAAGTAGAATCTGTAGACCTTCCA CACTGCCACCTGATTAAAGGAATTGAAGCTGGCTCTGAAGATATTGACATACTTCCCAAT GGTCTGGCTTTTTTTAGTGTGGGTCTAAAATTCCCAGGACTCCACAGCTTTGCACCAGAT AAGCCTGGAGGAATACTAATGATGGATCTAAAAGAAGAAAAACCAAGGGCACGGGAATTA AGAATCAGTCGTGGGTTTGATTTGGCCTCATTCAATCCACATGGCATCAGCACTTTCATA GACAACGATGACACAGTTTATCTCTTTGTTGTAAACCACCCAGAATTCAAGAATACAGTG GAAATTTTTAAATTTGAAGAAGCAGAAAATTCTCTGTTGCATCTGAAAACAGTCAAACAT GAGCTTCTTCCAAGTGTGAATGACATCACAGCTGTTGGACCGGCACATTTCTATGCCACA AATGACCACTACTTCTCTGATCCTTTCTTAAAGTATTTAGAAACATACTTGAACTTACAC TGGGCAAATGTTGTTTACTACAGTCCAAATGAAGTTAAAGTGGTAGCAGAAGGATTTGAT TCAGCAAATGGGATCAATATTTCACCTGATGATAAGTATATCTATGTTGCTGACATATTG GCTCATGAAATTCATGTTTTGGAAAAACACACTAATATGAATTTAACTCAGTTGAAGGTA CTTGAGCTGGATACACTGGTGGATAATTTATCTATTGATCCTTCCTCGGGGGACATCTGG GTAGGCTGTCATCCTAATGGCCAGAAGCTCTTCGTGTATGACCCGAACAATCCTCCCTCG TCAGAGGTTCTCCGCATCCAGAACATTCTATCTGAGAAGCCTACAGTGACTACAGTTTAT GCCAACAATGGGTCTGTTCTCCAAGGAAGTTCTGTAGCCTCAGTGTATGATGGGAAGCTG CTCATAGGCACTTTATACCACAGAGCCTTGTATTGTGAACTCTAA Clone variation with respect to NM_000305.2 >OriGene 5' read for NM_000305 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCCCACGGAGCTGCT GGCCAGGCCGGAGCGAGGCAGCGCGCCCGGCTCCCGCGCCATGGGGCGGCTGGTGGCTGT GGGCTTGCTGGGGATCGCGCTGGCGCTCCTGGGCGAGAGGCTTCTGGCACTCAGAAATCG ACTTAAAGCCTCCAGAGAAGTAGAATCTGTAGACCTTCCACACTGCCACCTGATTAAAGG AATTGAAGCTGGCTCTGAAGATATTGACATACTTCCCAATGGTCTGGCTTTTTTTAGTGT GGGTCTAAAATTCCCAGGACTCCACAGCTTTGCACCAGATAAGCCTGGAGGAATACTAAT GATGGATCTAAAAGAAGAAAAACCAAGGGCACGGGAATTAAGAATCAGTCGTGGGTTTGA TTTGGCCTCATTCAATCCACATGGCATCAGCACTTTCATAGACAACGATGACACAGTTTA TCTCTTTGTTGTAAACCACCCAGAATTCAAGAATACAGTGGAAATTTTTAAATTTGAAGA AGCAGAAAATTCTCTGTTGCATCTGAAAACAGTCAAACATGAGCTTCTTCCAAGTGTGAA TGACATCACAGCTGTTGGACCGGCACATTTCTATGCCACAAATGACCACTACTTCTCTGA TCCTTTCTTANAGTATTTAGAAACATACTTGAACTTACACTGGGCANATGTTGTTTACTA CAGTCCANATGAAGTTAAAGTGGTAGCAGAAGGATTTGATTCAGCANATGGGATCAATAT TTCACCTGGATGATAGTATATCTATGGTGCTGACATATAGGCTCATGAAATNCATGGTNT GGAAAAACACACTNATATGAANTTAACTCAGTTGAAAGGTACTTGAGCTGGATACACTGG NTGGATATTT >OriGene 3' read for NM_000305 unedited
NNCCCCAAGCTCTGNATCCGCGGCCGCAATCTAGCATCGAGTTTTTTTTTTTTTTTTTTG GGATTTTACCTACTCTTTAATATAACTCCAACTTTTTAATGGTAAACAAAGATGTAAGTA CAAAACATCAAAATACCCTATCAGTAGTTCTAAACAGCCATAGTAGTCACAGTGCCAGAA GTGAGGTCACTCACATTTTAAGGAAATATAATTCACTCTATTTCAGTGGAATCCATGTTC TGGCAGTTGGAAGGCAAAGGTGAGGCTTACTTTGCGCACAATGCATTCACTTTATTCCAA AGCAGATTTCTTCTCTGTCCCTTGCTTGGCATTTCAAACAACCTGCTCATCTCTCTTTTT TGTTAAAAGCGCTCTAAGAACTAAAAGGGCCGTTCCTTACTGGAATAAAATTAACTACAC ATGCCATACATTTCTGGGTCAATGTTGCTGGCCAACATTCCCTCAGAACTCACAATCCAT CGAACATTAATTGCTAAGTTATTGCACTTTTCTGCCAAAAGCACCATTCACAGTTCACCA TACAAGGCTCTGCGCTATAACAGCGCCTATGAGCAGCCTCCCATCATACACTGAGGCTAC AGAACTTCCTTGGGAACAGACTCACTGCCGCACACACTGCACTACTGCCCGCTTCCACAC AGAAGTTCCGGACGCCGAGAACCTCTGACTCGGGAGGATTGCTTCGGGTCATACACCAAG AGCCTTTGGCCCTTAAGACGACAGCCTACCCATATTGTCCCCCGAGGAAGGATCAATAGA TAACATATCCACCATGGTTTCCCGCCAACATACCTTTACTCGCACTAACCCATAACCAGG GCGGCCTTCCCACACCATGAACTTCATGTACCACCTCCCGACCCCCAATGTTATTCCTCC CAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000305 |
| Insert Size | 2450 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000305.2, NP_000296.2 |
| RefSeq Size | 1669 bp |
| RefSeq ORF | 1065 bp |
| Locus ID | 5445 |
| UniProt ID | Q15165 |
| Domains | Arylesterase |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways |
| Gene Summary | This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-oxododecanoyl)-Homoserine Lactone
,Schwarzer, C;Fu, Z;Morita, T;Whitt, AG;Neely, AM;Li, C;Machen, TE;,
J. Biol. Chem.
,PubMed ID 25627690
[PON2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222624 | PON2 (Myc-DDK-tagged)-Human paraoxonase 2 (PON2), transcript variant 1 |
CNY 3,656.00 |
|
| RC222624L1 | Lenti ORF clone of Human paraoxonase 2 (PON2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222624L2 | Lenti ORF clone of Human paraoxonase 2 (PON2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC222624L3 | Lenti ORF clone of Human paraoxonase 2 (PON2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222624L4 | Lenti ORF clone of Human paraoxonase 2 (PON2), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG222624 | PON2 (tGFP-tagged) - Human paraoxonase 2 (PON2), transcript variant 1 |
CNY 5,256.00 |
