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Methylmalonyl Coenzyme A mutase (MUT) (NM_000255) Human Untagged Clone
CAT＃: SC120001
MUT (untagged)-Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein
CNY 5,504.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MCM; MUT |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120001 sequence for NM_000255 edited (data generated by NextGen Sequencing)
ATGTTAAGAGCTAAGAATCAGCTTTTTTTACTTTCACCTCATTACCTGAGGCAGGTAAAA GAATCATCAGGCTCCAGGCTCATACAGCAACGACTTCTACACCAGCAACAGCCCCTTCAC CCAGAATGGGCTGCCCTGGCTAAAAAGCAGCTGAAAGGCAAAAACCCAGAAGACCTAATA TGGCACACCCCGGAAGGGATCTCTATAAAACCCTTGTATTCCAAGAGAGATACTATGGAC TTACCTGAAGAACTTCCAGGAGTGAAGCCATTCACACGTGGACCATATCCTACCATGTAT ACCTTTAGGCCCTGGACCATCCGCCAGTATGCTGGTTTTAGTACTGTGGAAGAAAGCAAT AAGTTCTATAAGGACAACATTAAGGCTGGTCAGCAGGGATTATCAGTTGCCTTTGATCTG GCGACACATCGTGGCTATGATTCAGACAACCCTCGAGTTCGTGGTGATGTTGGAATGGCT GGAGTTGCTATTGACACTGTGGAAGATACCAAAATTCTTTTTGATGGAATTCCTTTAGAA AAAATGTCAGTTTCCATGACTATGAATGGAGCAGTTATTCCAGTTCTTGCAAATTTTATA GTAACTGGAGAAGAACAAGGTGTACCTAAAGAGAAGCTTACTGGTACCATCCAAAATGAT ATACTAAAGGAATTTATGGTTCGAAATACATACATTTTTCCTCCAGAACCATCCATGAAA ATTATTGCTGACATATTTGAATATACAGCAAAGCACATGCCAAAATTTAATTCAATTTCA ATTAGTGGATACCATATGCAGGAAGCAGGGGCTGATGCCATTCTGGAGCTGGCCTATACT TTAGCAGATGGATTGGAGTACTCTAGAACTGGACTCCAGGCTGGCCTGACAATTGATGAA TTTGCACCAAGGTTGTCTTTCTTCTGGGGAATTGGAATGAATTTCTATATGGAAATAGCA AAGATGAGAGCTGGTAGAAGACTCTGGGCTCACTTAATAGAGAAAATGTTTCAGCCTAAA AACTCAAAATCTCTTCTTCTAAGAGCACACTGTCAGACATCTGGATGGTCACTTACTGAG CAGGATCCCTACAATAATATTGTCCGTACTGCAATAGAAGCAATGGCAGCAGTATTTGGA GGGACTCAGTCTTTGCACACAAATTCTTTTGATGAAGCTTTGGGTTTGCCAACTGTGAAA AGTGCTCGAATTGCCAGGAACACACAAATCATCATTCAAGAAGAATCTGGGATTCCCAAA GTGGCTGATCCTTGGGGAGGTTCTTACATGATGGAATGTCTCACAAATGATGTTTATGAT GCTGCTTTAAAGCTCATTAATGAAATTGAAGAAATGGGTGGAATGGCCAAAGCTGTAGCT GAGGGAATACCTAAACTTCGAATTGAAGAATGTGCTGCCCGAAGACAAGCTAGAATAGAT TCTGGTTCTGAAGTAATTGTTGGAGTAAATAAGTACCAGTTGGAAAAAGAAGACGCTGTA GAAGTTCTGGCAATTGATAATACTTCAGTGCGAAACAGGCAGATTGAAAAACTTAAGAAG ATCAAATCCAGCAGGGATCAAGCTTTGGCTGAACGTTGTCTTGCTGCACTAACCGAATGT GCTGCTAGCGGAGATGGAAATATCCTGGCTCTTGCAGTGGATGCATCTCGGGCAAGATGT ACAGTGGGAGAAATCACAGATGCCCTGAAAAAGGTATTTGGTGAACATAAAGCGAATGAT CGAATGGTGAGTGGAGCATATCGCCAGGAATTTGGAGAAAGTAAAGAGATAACATCTGCT ATCAAGAGGGTTCATAAATTCATGGAACGTGAAGGTCGCAGACCTCGTCTTCTTGTAGCA AAAATGGGACAAGATGGCCATGACAGAGGAGCAAAAGTTATTGCTACAGGATTTGCTGAT CTTGGTTTTGATGTGGACATAGGCCCTCTTTTCCAGACTCCTCGTGAAGTGGCCCAGCAG GCTGTGGATGCGGATGTGCATGCTGTGGGCATAAGCACCCTCGCTGCTGGTCATAAAACC CTAGTTCCTGAACTCATCAAAGAACTTAACTCCCTTGGACGGCCAGATATTCTTGTCATG TGTGGAGGGGTGATACCACCTCAGGATTATGAATTTCTGTTTGAAGTTGGTGTTTCCAAT GTATTTGGTCCTGGGACTCGAATTCCAAAGGCTGCCGTTCAGGTGCTTGATGATATTGAG AAGTGTTTGGAAAAGAAGCAGCAATCTGTATAA Clone variation with respect to NM_000255.3 >OriGene 5' read for NM_000255 unedited
TGAAACACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGAGTCGTCCGGCTG ACGCTGGCGGTGGCGCGGTTTGTGTGGGCTTGGTGAGGGCGGGGAGGCCTGGCTGTGTGG ATGTCTGACAGGTGAGGCGGGGGACGCAGAAGTGCAGCCGCCCTCTCCCACAGCGGAGTC CAAAACAGGCCTACCAGTCAGTTCTTATTTCTATTGGGTGTTTCCATGCTCCACCATGTT AAGAGCTAAGAATCAGCTTTTTTTACTTTCACCTCATTACCTGAGGCAGGTAAAAGAATC ATCAGGCTCCAGGCTCATACAGCAACGACTTCTACACCAGCAACAGCCCCTTCACCCAGA ATGGGCTGCCCTGGCTAAAAAGCAGCTGAAAGGCAAAAACCCAGAAGACCTAATATGGCA CACCCCGGAAGGGATCTCTATAAAACCCTTGTATTCCAAGAGAGATACTATGGACTTACC TGAAGAACTTCCAGGAGTGAAGCCATTCACACGTGGACCATATCCTACCATGTATACCTT TAGGCCCTGGACCATCCGCCAGTATGCTGGTTTTAGTACTGTGGAAGAAAGCAATAAGTT CTATAAGGACAACATTAAGGCTGGTCAGCAGGGATTATCAGTTGCCTTTGATCTGGCGAC ACATCGTGGCTATGATTCAGACAACCCTCGAGTTCGTGGTGATGTTGGAATGGCTGGAGT TGCTATTGACACTGTGGAAGATACCAAAATTCTTTTTGATGGAATTCCTTTANAAAAAAT GTCAGTTTCCATGACTATGAAATGGAGCAGTATTCCAGTTCTTGCAAATTNTATAGTAAC TGGAGAAGAACAAGGTGTACCTAAAGAGAGCTTACTGGTACCATNCANATGAATACTNAA GGATT >OriGene 3' read for NM_000255 unedited
TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGTGAAACTGTAT GTACATACTTATAGCATGACACCAGGCCTATAAGTAAGGTATTTTAAAGTAAAGCTTTCA AGGAAAGTACAAATCAGGTATTGAAATTAAATTGAAGACATAGCTTTACTCTCTTCTTTG ATCATAACTAAAATAATATTTTAGACAAAAGCTAAAACAAAAAGAGGATATTATACAGAT TGCTGCTTCTTTTCCAAACACTTCTCAATATCATCAAGCACCTGAACGGCAGCCTTTGGA ATTCGAGTCCCAGGACCAAATACATTGGAAACACCAACTTCAAACAGAAATTCATAATCC TGAGGTGGTATCACCCCTCCACACATGACAAGAATATCTGGCCGTCCAAGGGAGTTAAGT TCTTTGATGAGTTCAGGAACTAGGGTTTTATGACCAGCAGCGAGGGTGCTTATGCCCACA GCATGCACATCCGCATCCACAGCCTGCTGGGCCACTTCACGAGGAGTCTGGAAAAGAGGG CCTATGTCCACATCAAAACCAAGATCAGCAAATCCTGTAGCAATAACTTTTGCTCCTCTG TCATGGCCATCTTGTCCCATTTTTGCTACAAGAAGACGAGGTCTGCGACCTTCACGTTCC ATGAATTTATGAACCCTCTTGATAGCAGATGTTATCTCTTTACTTTCTCCAAATTCCTGG CGATATGCTCCACTCACCATTCGATCATTCGCTTTATGTTCACCAAATACCTTTTTCAGG GCATCTGTGATTTCTCCACTGTACATCTTGCCCGAGATGCATCCACTTGCAGAGCCAAGA TTTTCCATCTCCGCTACCACCACATCCCGTTATTGCAGCAAGACAACGTTCAGCCAAGCT TGATCCCTGCTGAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000255 |
| Insert Size | 2710 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000255.1, NP_000246.1 |
| RefSeq Size | 2798 bp |
| RefSeq ORF | 2253 bp |
| Locus ID | 4594 |
| UniProt ID | P22033 |
| Domains | MM_CoA_mutase, B12-binding |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation |
| Gene Summary | This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
TAT-MTS-MCM fusion proteins reduce MMA levels and improve mitochondrial activity and liver function in MCM-deficient cells
,Erlich-Hadad, T;Hadad, R;Feldman, A;Greif, H;Lictenstein, M;Lorberboum-Galski, H;,
J. Cell. Mol. Med.
,PubMed ID 29265583
[MMUT]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201972 | MUT (Myc-DDK-tagged)-Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein |
CNY 5,496.00 |
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| RC201972L1 | Lenti ORF clone of Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
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| RC201972L2 | Lenti ORF clone of Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
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| RC201972L3 | Lenti ORF clone of Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC201972L4 | Lenti ORF clone of Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
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| RG201972 | MUT (tGFP-tagged) - Human methylmalonyl CoA mutase (MUT), nuclear gene encoding mitochondrial protein |
CNY 7,096.00 |
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