PTPRN2 (NM_002847) Human Untagged Clone
CAT#: SC120495
PTPRN2 (untagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1
CNY 10,608.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2 |
Vector | pCMV6-XL6 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC120495 sequence for NM_002847 edited (data generated by NextGen Sequencing)
ATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCACGCGTCCTG CCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTG CTCGAGGAGGGCCTCTGCGGAGCGTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGG TGCCAGAAGGTTCCGGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAG CGCCTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTAT ACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCT GAAGCATCCAGCCCAGCCAGGCCCTCAAAACACAGCGTTGGCAGCGAGAGGAGGTACAGT CGGGAGGGCGGTGCTGCCCTGGCCAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCC CTGTCCCAGGCCCCAGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCC CCCGCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCACACGTCT GCGCTGACCTACCCTCCCGGGCCCCGGACCCAGCTCCGCGAGGACCTCCTGCCGCGGACC CTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTAAGGTGGACAGTGGTGTGGACAGACAC CATCTGATGGCGGCCCTCAGTGCCTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAG GGCAGCCTGGAGCCACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTG GCACCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCCTCTAGC ACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGCAGAGGCAGCCGGCTGAG GTGAGGGGCCTGAATGGCCTGGAGCTGGACGGCATGGCCGAGCTGATGGCTGGCCTGATG CAAGGCGTGGACCATGGAGTAGCTCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCT GGAGAACAGGCGGATGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGA GTGCAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACACTCGGG GGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCCTCCCCTTTGCAAGGCCC CTCGACATGGAGAGGAAGAAGTCCGAGCACCCTGAGTCTTCCCTGTCTTCAGAAGAGGAG ACTGCCGGAGTGGAGAACGTCAAGAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAG CCGCATTCGGAGCCCGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCC TCGAAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGCCTGCAA TTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCGTGACAGACAGAGACCCC CTGCGCCCCGAGGAAGGAAGGCGGCTGGTGGAGGACGTCGCCCGCCTCCTGCAGGTGCCC AGCAGTGCGTTCGCTGACGTGGAGGTTCTCGGACCAGCAGTGACCTTCAAAGTGAGCGCC AATGTCCAAAACGTGACCACTGAGGATGTGGAGAAGGCCACAGTTGACAACAAAGACAAA CTGGAGGAAACCTCTGGACTGAAAATTCTTCAAACCGGAGTCGGGTCGAAAAGCAAACTC AAGTTCCTGCCTCCTCAGGCGGAGCAAGAAGACTCCACCAAGTTCATCGCGCTCACCCTG GTCTCCCTCGCCTGCATCCTGGGCGTCCTCCTGGCCTCTGGCCTCATCTACTGCCTCCGC CATAGCTCTCAGCACAGGCTGAAGGAGAAGCTCTCGGGACTAGGGGGCGACCCAGGTGCA GATGCCACTGCCGCCTACCAGGAGCTGTGCCGCCAGCGTATGGCCACGCGGCCACCAGAC CGACCTGAGGGCCCGCACACGTCACGCATCAGCAGCGTCTCATCCCAGTTCAGCGACGGG CCGATCCCCAGCCCCTCCGCACGCAGCAGCGCCTCATCCTGGTCCGAGGAGCCTGTGCAG TCCAACATGGACATCTCCACCGGCCACATGATCCTGTCCTACATGGAGGACCACCTGAAG AACAAGAACCGGCTGGAGAAGGAGTGGGAAGCGCTGTGCGCCTACCAGGCGGAGCCCAAC AGCTCGTTCGTGGCCCAGAGGGAGGAGAACGTGCCCAAGAACCGCTCCCTGGCCGTGCTG ACCTATGACCACTCCCGGGTCCTGCTGAAGGCGGAGAACAGCCACAGCCACTCAGACTAC ATCAACGCTAGCCCCATCATGGATCACGACCCGAGGAACCCCGCGTACATCGCCACCCAG GGACCGCTGCCCGCCACCGTGGCTGACTTTTGGCAGATGGTGTGGGAGAGCGGCTGCGTG GTGATCGTCATGCTGACACCCCTCGCGGAGAACGGCGTCCGGCAGTGCTACCACTACTGG CCGGATGAAGGCTCCAATCTCTACCACATCTATGAGGTGAACCTGGTCTCCGAGCACATC TGGTGTGAGGACTTCCTGGTGAGGAGCTTCTATCTGAAGAACCTGCAGACCAACGAGACG CGCACCGTGACGCAGTTCCACTTCCTGAGTTGGTATGACCGAGGAGTCCCTTCCTCCTCA AGGTCCCTCCTGGACTTCCGCAGAAAAGTAAACAAGTGCTACAGGGGCCGTTCTTGTCCA ATAATTGTTCATTGCAGTGACGGTGCAGGCCGGAGCGGCACCTACGTCCTGATCGACATG GTTCTCAACAAGATGGCCAAAGGTGCTAAAGAGATTGATATCGCAGCGACCCTGGAGCAC TTGAGGGACCAGAGACCCGGCATGGTCCAGACGAAGGAGCAGTTTGAGTTCGCGCTGACA GCCGTGGCTGAGGAGGTGAACGCCATCCTCAAGGCCCTTCCCCAGTGA Clone variation with respect to NM_002847.3 622 t=>c;897 c=>t;974 g=>a;999 t=>c >OriGene 5' read for NM_002847 unedited
GCCCCGTTGACGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTC ATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGG CACGAGGGAGGAGCCGGCGGCGCGCGCCTCCCTGGGCCCGGACTCGGCCGCCTCCCGCCG CCTCCCGCGCGGCCATGGACTGAGCGCCGCCGGCCAGGCCGCGGGGATGGGGCCGCCGCT CCCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCACGCGTCCTGCCTGCCGCCCCTTC GTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTGCTCGAGGAGGGCCT CTGCGGAGCGTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGGTGCCAGAAGGTTCC GGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAGCGCCTGCGCGTGGC GTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTATACTCAGTATGTGAT GGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCTGAAGCATCCAGCCC AGCCAGGCCCTCAAACACAGCGTTGGCAGCGAGAGGAGGTACAGTCGGGAGGGCGGTGCT GNCCTGGNNCAACGCCTNCGACGCCACCTGGCCTTTCTGGGAGCCCTGTNCCAGGCCCCA GCCTCAGACGTGCTCGCCAGGACCATACNGNGCANGACAGACCCCCGCCTGAGGTGATGA CCGCTCCTNCGAGAGCATCCTGACCTATGTGGNCCACACGTNTGCGCTGACCTACCCCTC CGGNCCCCGGACCAGCTCCGCGAGGACCCTCTGGCGGGNACCCTCGCCAGCTNCAGCCAG ATGAGCTCAGCCCTAGGTGGAACGGGGNNTGGGGACAGAACCCCATCTGATGGCGGCCCT CAGTGGCTATGCTGGCCAGAGGCCCCAGCTCCCGCGGGGGGAGGGCAAGCTGGAGGCCAC GAACCTNNTGGGTGCACCTNAAA >OriGene 3' genomic read for NM_002847 unedited
ACTATGGTACCGCGGCCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTGTGAAATC AGAGTTTAATATGACACAATTAAATATATTTGTATATCTCACACCGGAGGTTTCTCTTCA AACATAAGGAGTTAGAAATTACAAGTAGGCATATGCTTCCTATATTCAGATAAATTCATT TCGATTAATTAAATTCCAGATAGAGAGAAGTAATTTTGGAAAAGAAATGATAGCTATATT AAAGCAGATATTCATTACAATACCATGTAGAGACATAAGCAATATTTTGGCATCATTCTG TCCGCTCAGTAGGCCGTGTTCCCTCTGGTAGGGCCTTTGGAGAGTACCATCTATCTAAGA TGGAGGAATGCTGTGGGAAGGGCGGGATGGAGGTGCGTTTTCTACGCTGAACCCCACACA GGAAATCTGCAGCCCACACAGCTGCCTCTGCGCCGCCTTCCATGTGATCATCCTGGTCAA TGAAGTGAATTGTCCTATTTCTGGGGTAGGGGGTGATGGCGAATCGGATACTCAAATGTT ATTTTGTCAAATCCGAATCATCTCTACGTGCTTAGGTTTACATGATGTCAAAACACGTGG TTCATTAAGTGATCCCGGGAAGAGGGGCAGGGCCGGTCGGCTGGTTTCTCACTTCCCTTC CAGGCTCTACGCAGTGCGTGCAGGTCGCCCTGATCTCTCCCGGGAGGGGAATGCTCGCAG CCCTCTCCGAGNTGCCCTGATCTCCTTCTCTCCCAGAGGGAAATGGTCCCTCTCTGGGGC CCCACAGTCCCGGACGTGCCTGGAGAGCCAGCGGGGCCTGGCAGGGNTCGTGTGCTCCCG GGGACCCTCTAGCTTGCTCAAGCCCAGATTGTTCTTCCTGTTGTGGTATCTCACAGGTAG CTTCACGGGGCATCGTTTTCATACGGAAAAACATTATTTACT |
Restriction Sites | NotI-NotI |
ACCN | NM_002847 |
Insert Size | 5500 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002847.2, NP_002838.1 |
RefSeq Size | 4767 bp |
RefSeq ORF | 3048 bp |
Locus ID | 5799 |
UniProt ID | Q92932 |
Domains | Y_phosphatase, PTPc_motif |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | Type I diabetes mellitus |
Gene Summary | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Transcript Variant: This variant (1) encodes isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC217690 | PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1 |
CNY 11,304.00 |
|
RC217690L3 | Lenti-ORF clone of PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1 |
CNY 12,070.00 |
|
RC217690L4 | Lenti-ORF clone of PTPRN2 (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1 |
CNY 12,070.00 |
|
RG217690 | PTPRN2 (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1 |
CNY 12,904.00 |