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CACNB3 (NM_000725) Human Untagged Clone
CAT＃: SC122090
CACNB3 (untagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAB3; CACNLB3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000725 edited
GTCGAGAGCGGGTGGGGGGAGCGGTGATCTGAGCTCCGAGCAGCTGGTCTTCGCGGCTCG CTCCCTCCTTCGCGCTCTCTCGCTCCCTGCCGCCGCCCGCAGGGCTGCGGGGCTCGGTGG CATCTCCCGGGCGCGGCCCGCAGTCCTTGCCCCTGCCTCCGGGCCGCTCCCGCCCCCGGC GCCGCTCGCTCCCCCGACCCGGACTCCCCCATGTATGACGACTCCTACGTGCCCGGGTTT GAGGACTCGGAGGCGGGTTCAGCCGACTCCTACACCAGCCGCCCATCTCTGGACTCAGAC GTCTCCCTGGAGGAGGACCGGGAGAGTGCCCGGCGTGAAGTAGAGAGCCAGGCTCAGCAG CAGCTCGAAAGGGCCAAGCACAAACCTGTGGCATTTGCGGTGAGGACCAATGTCAGCTAC TGTGGCGTACTGGATGAGGAGTGCCCAGTCCAGGGCTCTGGAGTCAACTTTGAGGCCAAA GATTTTCTGCACATTAAAGAGAAGTACAGCAATGACTGGTGGATCGGGCGGCTAGTGAAA GAGGGCGGGGACATCGCCTTCATCCCCAGCCCCCAGCGCCTGGAGAGCATCCGGCTCAAA CAGGAGCAGAAGGCCAGGAGATCTGGGAACCCTTCCAGCCTGAGTGACATTGGCAACCGA CGCTCCCCTCCGCCATCTCTAGCCAAGCAGAAGCAAAAGCAGGCGGAACATGTTCCCCCA TATGACGTGGTGCCCTCCATGCGGCCTGTGGTGCTGGTGGGACCATCTCTGAAAGGTTAT GAGGTCACAGACATGATGCAGAAGGCTCTCTTCGACTTCCTCAAACACAGATTTGATGGC AGGATCTCCATCACCCGAGTCACAGCCGACCTCTCCCTGGCAAAGCGATCTGTGCTCAAC AATCCGGGCAAGAGGACCATCATTGAGCGCTCCTCTGCCCGCTCCAGCATTGCGGAAGTG CAGAGTGAGATCGAGCGCATATTTGAGCTGGCCAAATCCCTGCAGCTAGTAGTGTTGGAC GCTGACACCATCAACCACCCAGCACAGCTGGCCAAGACCTCGCTGGCCCCCATCATCGTC TTTGTCAAAGTGTCCTCACCAAAGGTACTCCAGCGTCTCATTCGCTCCCGGGGGAAGTCA CAGATGAAGCACCTGACCGTACAGATGATGGCATATGATAAGCTGGTTCAGTGCCCACCG GAGTCATTTGATGTGATTCTGGATGAGAACCAGCTGGAGGATGCCTGTGAGCACCTGGCT GAGTACCTGGAGGTTTACTGGCGGGCCACGCACCACCCAGCCCCTGGCCCCGGACTTCTG GGTCCTCCCAGTGCCATCCCGGGACTTCAGAACCAGCAGCTGCTGGGGGAGCGTGGCGAG GAGCACTCCCCCCTTGAGCGGGACAGCTTGATGCCCTCTGATGAGGCCAGCGAGAGCTCC CGCCAAGCCTGGACAGGATCTTCACAGCGTAGCTCCCGCCACCTGGAGGAGGACTATGCA GATGCCTACCAGGACCTGTACCAGCCTCACCGCCAACACACCTCGGGGCTGCCTAGTGCT AACGGGCATGACCCCCAAGACCGGCTTCTAGCCCAGGACTCAGAGCACAACCACAGTGAC CGGAACTGGCAGCGCAACCGGCCTTGGCCCAAGGATAGCTACTGACAGCCTCCTGCTGCC CTACCCTGGCAGGCACAGGCGCAGCTGGCTGGGGGGCCCACTCCAGGCAGGGTGGCGTTA GACTGGCATCAGGCTGGCACTAGGCTCAGCCCCCAAAACCCCCTGCCCAGCCCCAGCTTC AGGGCTGCCTGTGGTCCCAAGGTTCTGGGAGAAACAGGGGACCCCCTCACCTCCTGGGCA GTGACCCCTACTAGGCTCCCATTCCAGGTACTAGCTGTGTGTTCTGCACCCCTGGCACCT TCCTCTCCTCCCACACAGGAAGCTGCCCCACTGGGCAGTGCCCTCAGGCCAGGATCCCCT TAGCAGGGTCCTTCCCACCAGACTCAGGGAAGGGATGCCCCATTAAAGTGACAAAAGGGT GGGGTGTGGGCACCATGGCATGAGGAAGAAACAAGGTCCCTGAGCAGGCACAAGTCCTGA CAGTCAAGGGACTGCTTTGGCATCCAGGGCCTCCAGTCACCTCACTGCCATACATTAGAA ATGAGACAATCAAAGCCCCCCCAGGGTGGCACACCCATCCGTTTGCTGGGGTGTGGCAGC CACATCCAAGACTGGAGCAGCAGGCTGGCCACGCTCGGGCCAGAGAGAGCTCACAGCTGA AGCTCTTGGAGGGAAGGGCTCTCCTCACCCTGCCAGGAAGCTTCTTAACATGTGACAGGA CCAGGGACCAGGAGCATGGTGAAGCCAAGTGGCAGATGGGAGCCAACCTGGATGGGGGTT TGGGGAAGGAGGGCATGTGTAGCAGAGAACTTAGGGGGGCCTCCTTGCCTTTCTCATTCT TTTGCCCTGCATCCTGTCATTTCTGTTCTTGTCCCTCATACATCTTTGGAGAACCGGGCT CCAGACTTTGTTCCCTGACTCATAGCTGCCGCTTGTTAGGTTAGGGTTAGATGGGGAGAG ACAGGGCACAGAGGACCTGTCTCCCCGGCTACTCTTGCCTTATGGCTCTAGTGTGTGACC TACAGAGCATGCTCCACAAGCCCCTGCCTCACCTCACTGTCATCACTAATAAACATCATG CACAGTCAAAAAAAAAAAAAAAA >OriGene 5' read for NM_000725 unedited
AAAACGTTCGNCTTTTGTAATACGACTCACTATAGGCGGCCGCATAACTTCGTATAGCAT ACATTATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGG TGGGGGGAGCGGTGATCTGAGCTCCGAGCAGCTGGTCTTCGCGGCTCGCTCCCTCCTTCG CGCTCTCTCGCTCCCTGCCGCCGCCCGCAGGGCTGCGGGGCTCGGTGGCATCTCCCGGGC GCGGCCCGCAGTCCTTGCCCCTGCCTCCGGGCCGCTCCCGCCCCCGGCGCCGCTCGCTCC CCCGACCCGGACTCCCCCATGTATGACGACTCCTACGTGCCCGGGTTTGAAGACCTCGGA GCAGGTTCAGCCGACTCCTAACCAGCCGGCCATCTCTGGACTCAGACCGTCTCCTTGGNA GAGACCGGGAGAGTGCCCCGCGTGGAGTANAGAGCCCAGCTCAACAACAGCTCTGAAAGG CCAAGCCACACCTGTGGCATTTGCGGTGAAGACCCATGGCAGCTCCCGTGGCCTTCTTGA TGAAGAGTGGCCCAGTCAGGGCTTTGAGTCAACTTTGAGCCCAAGGATTTCTGCCCCTTA AGAGGAGTTCAACCATGACTGTGGGATCGGCCGGCTAGTGAAAAAGAGGCGGGGACCATT GCCTTNTTCCCCAAACCCAAAAGCCCTGGGAGACTTCGGCTCTCACCCGAGCCCAAGGGC CGGGATCTGGGAAACCTTTCCGCCTGGATGAACTTTGGAAACGAAGCTCTCCCTCGCCTT TTTTGGCAAGCGAAACCAAAGCCGGCGGGACACGTTCCCCCCTTGAACTGGGGCCCCTCC ATTCGGCCTGTGGTGCTCGGGGAACCCTTCCTGAAGGTTTTAAGGGCCAAACCTGGTCCA AAGGCCTCTTTG >OriGene 3' read for NM_000725 unedited
ACCCTATACTTTGNNACCGCGGCCGCATNCTANGATCGACAGNCTTGATATCGGTACCGG GCCCCCCCTCGAAGTTCAGGCCCTTATGGCCGGATCCAGCGCTGGAGAGTTTTTTTTTTT TTTTTGACTGTGCATGATGTTTATTAGTGATGACAGTGAGGTGAGGCAGGGGCTTGTGGA GCATGCTCTGTAGGTCACACACTAGAGCCATAAGGCAAGAGTAGCCGGGGAGACAGGTCC TCTGTGCCCTGTCTCTCCCCATCTAACCCTAACCTAACAAGCGGCAGCTATGAGTCAGGG AACAAAGTCTGGAGCCCGGTTCTCCAAAGATGTATGAGGGACAAGAACAGAAATGACAGG ATGCAGGGCAAAAGAATGAGAAAGGCAAGGAGGCCCCCCTAAGTTCTCTGCTACACATGC CCTCCTTCCCCAAACCCCCATCCAGGTTGGCTCCCATCTGCCACTTGGCTTCACCATGCT CCTGGTCCCTGGTCCTGTCACATGTTAAGAAGCTTCCTGGCAGGGTGAGGAGAGCCCTTC CCTCCAAGAGCTTCAGCTGTGAGCTCTCTCTGGCCCGAGCGTGGCCAGCCTGCTGCTCCA GTCTTGGATGTGGCTGCCACACCCCAGCAAACGGATGGGTGTGCCACCCTGGGGGGGCTT TGATTGTCTCATTTCTAATGTATGGCAGTGAGGTGACTGGAGGCCCTGGATGCCAAAGCA GTCCCTTGACTGTCAGGACTTGTGCCTGCTCAGGGACCTTGTTTCTTTCTCATGCCTTGG TGCCCACCCCCCAACCCTTTGGCACTTTTATGGGGGCATCCCCTTCCCTGATTCCGGTGG GGAAGAACCCTGCTAAGGTGATCCTGCCCTGAAGGCCCTTCCACTTGGCGCCTCTTCCTG TGTGGGC |
| Restriction Sites | Please inquire |
| ACCN | NM_000725 |
| Insert Size | 1455 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found that the protein associated with this clone matches NM_000725 perfectly. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000725.2, NP_000716.2 |
| RefSeq Size | 2714 bp |
| RefSeq ORF | 1455 bp |
| Locus ID | 784 |
| UniProt ID | P54284 |
| Domains | Ca_channel_B, GuKc |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H
,Berecki, G;Motin, L;Adams, DJ;,
Neuropharmacology
,PubMed ID 27245500
[CACNB3]
|
|
Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and a-conotoxin Vc1.1 via GABAB receptor activation
,Berecki, G;McArthur, JR;Cuny, H;Clark, RJ;Adams, DJ;,
J. Gen. Physiol. 465-79 143 4. April 2014
,PubMed ID 24688019
[CACNB3]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207229 | CACNB3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 5,488.00 |
|
| RC207229L1 | Lenti-ORF clone of CACNB3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 7,888.00 |
|
| RC207229L2 | Lenti-ORF clone of CACNB3 (mGFP-tagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 5,890.00 |
|
| RC207229L3 | Lenti-ORF clone of CACNB3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 5,890.00 |
|
| RC207229L4 | Lenti-ORF clone of CACNB3 (mGFP-tagged)-Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 7,888.00 |
|
| RG207229 | CACNB3 (tGFP-tagged) - Human calcium channel, voltage-dependent, beta 3 subunit (CACNB3), transcript variant 1 |
CNY 7,088.00 |
