ASCC1 (BC012291) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit P50; ASC1p50; CGI-18; OTTHUMP00000019781; OTTHUMP00000019782; OTTHUMP00000019783; RP11-150D20.4
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC012291 edited AGAGAACGCGCTCGCGTAGAGGAATTCCGGGTCCTCCTCCTCGCCCTACCTTGGTTTACC TGCAGCCGCCTAGTCCTCTTCTCCTTCTCTTTGATGATTCAGGGCCTCGGCTTCCCTCAC GGGCATAATTGGAATATCATTTGGAGAAAGTGTCATGGAAGTTCTGCGTCCACAGCTTAT AAGAATTGATGGCCGGAATTACAGGAAGAATCCAGTCCAAGAACAGACCTATCAACATGA AGAAGATGAAGAGGACTTCTATCAAGGCTCCATGGAGTGTGCTGATGAGCCCTGTGATGC CTACGAGGTGGAGCAGACCCCACAAGGATTCCGGTCTACTTTGAGGGCCCCCAGCTTGCT CTATAAGCATATAGTTGGAAAGAGAGGGGACACTAGGAAGAAAATAGAAATGGAGACCAA AACTTCTATTAGCATTCCTAAACCTGGACAAGACGGGGAAATTGTAATCACTGGCCAGCA TCGAAATGGTGTAATTTCAGCCCGAACACGGATTGATGTTCTTTTGGACACTTTTCGAAG AAAGCAGCCCTTCACTCACTTCCTTGCCTTTTTCCTCAATGAAGTTGAGGTTCAGGAAGG ATTCCTGAGATTCCAGGAGGAAGTACTGGCGAAGTGCTCCATGGATCATGGGGTTGACAG CAGCATTTTCCAGAATCCTAAAAAGCTTCATCTAACTATTGGGATGTTGGTGCTTTTGAG TGAGGAAGAGATCCAGCAGACATGTGAGATGCTACAGCAGTGTAAAGAGGAATTCATTAA TGATATTTCTGGGGGTAAACCCCTAGAAGTGGAGATGGCAGGGATAGAATACATGAATGA TGATCCTGGCATGGTGGATGTTCTTTACGCCAAAGTCCATATGAAAGATGGCTCCAACAG GCTACAAGAATTAGTTGATCGAGTGCTGGAACGTTTTCAGGCATCTGGACTAATAGTGAA AGAGTGGAATAGTGTGAAACTGCATGCTACAGTTATGAATACACTATTCAGGAAAGACCC CAATGCTGAAGGCAGGTACAATCTCTACACAGCGGAAGGCAAATATATCTTCAAGGAAAG AGAATCATTTGATGGCCGAAATATTTTAAAGTTGTTTGAGAACTTCTACTTTGGCTCCCT AAAGCTGAATTCAATTCACATCTCTCAGAGGTTCACCGTAGACAGCTTTGGAAACTACGC TTCCTGTGGACAAATTGACTTCTCCTGAGGTGGATCTTGGAAAGCACTAGAAACTAAACA TCTTCACCAGGTGCTGAAGAAAAGTGTCTTCGTTTTAATTGCCAAGCAGGGATGTGGACA TTTGGATGGTGACTTCCCTGGGTGGTTCCCCATAGATTCACCATTGCCTCTAATGGTGTC TACACCCGTCATACTACCAGCTGAGATGGTGGTGGGCATAAGGAGAATTTGTGCCTATAA CCCTTAGTGTGTTCTGGTTTTTTTTCTTTTAATTTTTAAATTGTCGTAAAATACTCATAA AACATACTGTCTTCACCATTTTTAAGTGCACAGTTCAGTAACGTTAACTGTTAATACATT CATAATGCTGTGTGGCCGTCACCGCCGTCCATCTCCATAGGCTTCTCAGCTTGTAAAATG GAAACTGTACCCATTAAACAGTAATTCCCACTCCTCCCAGAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC012291 unedited NGTTGGATTTGTATACGACTCATATGGGCGGCCGCGCATTCANATCTGGTACCGGTCCGG AATTCCCGGGATATCGTCGACCCACGCGTCCGAGAGAACGCGCTCGCGTAGAGGAATTCC GGGTCCTCCTCCTCGCCCTACCTTGGTTTACCTGCAGCCGCCTAGTCCTCTTCTCCTTCT CTTTGATGATTCAGGGCCTCGGCTTCCCTCACGGGCATAATTGGAATATCATTTGGAGAA AGTGTCATGGAAGTTCTGCGTCCACAGCTTATAAGAATTGATGGCCGGAATTACAGGAAG AATCCAGTCCAAGAACAGACCTATCAACATGAAGAAGATGAAGAGGACTTCTATCAAGGC TCCATGGAGTGTGCTGATGAGCCCTGTGATGCCTACGAGGTGGAGCAGACCCCACAAGGA TTCCGGTCTACTTTGAGGGCCCCCAGCTTGCTCTATAAGCATATAGTTGGAAAGAGAGGG GACACTAGGAAGAAAATAGAAATGGAGACCAAAACTTCTATTAGCATTCCTAAACCTGGA CAAGACGGGGAAATTGTAATCACTGGCCAGCATCGAAATGGTGTAATTTCAGCCCGAACA CGGATTGATGTTCTTTTGGACACTTTTCGAAGAAAGCAGCCCTTCACTCACTTCCTTGCC TTTTTCCTCAATGAAGTTGNAGGTTCAGGAAGATTCCTGAGATTCCAGGAGGAAGTACTG GCGAAGTGCTCCATGGATCATGGGGTTGACAGCAGCATTTTCCAGAATCCTANAAGCTTC ATCTAACTATTGGGATGNTNNGTGCTTTGAGTGANGGAAGAGATCCAGCAGACATGTGAG ATGCTACAGCAGTGTAAAGAAGGAATTCATTAATGANNATTTCTGGGGGGGTAACCCCCT ANAAGTGGAGATGGCAGGNATAGAAA
Restriction Sites	Please inquire
ACCN	BC012291
Insert Size	1678 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC012291.1, AAH12291.1
RefSeq Size	1678 bp
Locus ID	51008
Gene Summary	This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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