C6orf57 (SDHAF4) (BC018085) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	chromosome 6 open reading frame 57
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for NM_145267 edited GCGGGGGCTCGGGGAGTCGGCGCCATGACCCCATCGAGGCTTCCCTGGTTGCTTAGCTGG GTCTCGGCCACGGCGTGGAGAGCGGCAAGATCACCCCTTCTGTGTCATTCTCTGAGGAAA ACAAGTTCTTCTCAAGGAGGAAAGTCTGAACTTGTCAAACAGTCCCTTAAGAAGCCGATG TTACCAGAAGGTCGTTTTGATGCACCAGAGGATTCCCATTTAGAGAAAGAACCACTGGAA AAATTTCCAGATGATGTTAATCCAGTGACCAAAGAAAAAGGTGGACCCAGGGGCCCAGAA CCTACCCGATATGGAGATTGGGAACGAAAAGGACGCTGTATTGATTTTTAAGTCGCATAT TCTTTAACTTCAATATTGTTTTCTGAATATGTACATCTGAATTAACTTATTTATGATTAT TTTCTTTCTTTATATCCTTTATGTCGTGTAGTTTGTATAATGTGTTTAAATATATATATA TATGATGGCTTTGGAAGAAAATATGCTGCTGTAAATTAGGAAAGGGAGACCAGCCTGACC AATATGGAGAAATCTCGCCTTTGCTGAAAATACAAAATTAGCCAGGCGTGGTGGCATGCA CCTGTAATCCCAACTACTCTGGAGGCTGAGGCAGGAGAATGGCTTGAACCCAGGAGGTGG AGGTTGCGGTGAGCTGAGGTCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACT CCGTCTCAAAAAAAAAGATAGGAAAGGGAAAATATTTTTTCATTAACATATATTAATTTA ATGAGTATAGAAATGATTCTTGTTTTTTTGAGACGGAGTCTCTCTCTCTCACCCAGGCTG GAGTGGAGTGGCGCTATCCCAGCTCACTGCAACTTCCGCCCCGCCAGGTTCGGGCAATTC TCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGACACCCACCATTGCGCCTGGCTAAT TTTTGTATTTTTAGTAAAGACAAGGTTTCACCATGTTAGCCAGGCTGGTCTCGAACTCCT GACCTCAGTTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTGCAGGTGTGAGCCA CCACGCCCAGCCTAGAAATGATTCTTAGAGCTGTAGGCCTTTACTTCATCATTTTTCAGT TTAAATTAATCAGTTGCTTATAAAATGCATACATAAATAAAATAATTTTTAAAAAAAAAA AAGAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC018085 unedited TCGAGAGCGGGCGGGGGCTCGGGGAGTCGGCGCCATGACCCCATCGAGGCTTCCCTGGTT GCTTAGCTGGGTCTCGGCCACGGCGTGGAGAGCGGCAAGATCACCCCTTCTGTGTCATTC TCTGAGGAAAACAAGTTCTTCTCAAGGAGGAAAGTCTGAACTTGTCAAACAGTCCCTTAA GAAGCCGATGTTACCAGAAGGTCGTTTTGATGCACCAGAGGATTCCCATTTAGAGAAAGA ACCACTGGAAAAATTTCCAGATGATGTTAATCCAGTGACCAAAGAAAAAGGTGGACCCAG GGGCCCAGAACCTACCCGATATGGAGATTGGGAACGAAAAGGACGCTGTATTGATTTTTA AGTCGCATATTCTTTAACTTCAATATTGTTTTCTGAATATGTACATCTGAATTAACTTAT TTATGATTATTTTCTTTCTTTATATCCTTTATGTCGTGTAGTTTGTATAATGTGTTTAAA TATATATATATATGATGGCTTTGGAAGAAAATATGCTGCTGTAAATTAGGAAAGGGAGAC CAGCCTGACCAATATGGAGAAATCTCGCCTTTGCTGAAAATACAAAATTAGCCAGGCGTG GTGGCATGCACCTGTAATCCCA
Restriction Sites	Please inquire
ACCN	BC018085
Insert Size	1300 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC018085.1, AAH18085.1
RefSeq Size	1218 bp
Locus ID	135154
Protein Families	Secreted Protein
Gene Summary	Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit SDHA in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDHB into the SDH catalytic dimer (By similarity).[UniProtKB/Swiss-Prot Function]

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