CHMP4C (BC014321) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	chromatin modifying protein 4C; MGC108776; Shax3; Snf7 homologue associated with Alix 3
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC014321 edited GGGGGGAAATGCCCTGGAGTGTGTGTCACCTGTCCAGGACGACTTGTTGATTCCCAGGAG GGCCGCCTTTCCGGTCTGGGTCCCCGAGAGGACTGCCTTGCTCACCTGTCCCCTCGGCGC GGCCCCGGGGAGCTCCCGAGAGGCCCCCGGGATCGCTGGCCCTCCGAACTCCACAGCAAT GAGCAAGTTGGGCAAGTTCTTTAAAGGGGGCGGCTCTTCTAAGAGCCGAGCCGCTCCCAG TCCCCAGGAGGCCCTGGTCCGACTTCGGGAGACTGAGGAGATGCTGGGCAAGAAACAAGA GTACCTGGAAAATCGAATCCAGAGAGAAATCGCCCTGGCCAAGAAGCACGGCACGCAGAA TAAGCGAGCTGCATTACAGGCACTAAAGAGAAAGAAGAGGTTCGAGAAACAGCTCACTCA GATTGATGGCACACTTTCTACCATTGAGTTCCAGAGAGAAGCCCTGGAGAACTCACACAC CAACACTGAGGTGTTGAGGAACATGGGCTTTGCAGCAAAAGCGATGAAATCTGTTCATGA AAACATGGATCTGAACAAAATAGATGATTTGATGCAAGAGATCACAGAGCAACAGGATAT CGCCCAAGAAATCTCAGAAGCATTTTCTCAACGGGTTGGCTTTGGTGATGACTTTGATGA GGATGAGTTGATGGCAGAACTTGAAGAATTGGAACAGGAGGAATTAAATAAGAAGATGAC AAATATCCGCCTTCCAAATGTGCCTTCCTCTTCTCTCCCAGCACAGCCAAATAGAAAACC AGGCATGTCGTCCACTGCACGTCGATCCCGAGCAGCATCTTCCCAGAGGGCAGAAGAAGA GGATGATGATATCAAACAATTGGCAGCTTGGGCTACCTAAACTAAAACACATTTTTGATA CCTAAATTAATGAGCTATAGATAAAATATAAAAAATGTTTTTACCAAGTTCAGAAGTTAA CAAAGACTCTGCTTTATAATTATATTGAATGAATAATTGTGTTTTAAGCCTCCTAAGTAA AAGTAAAAAAGGAGTCATGTGCATACATAGAATCAGTGATGGAGGCCAGGCACGGTATCT CATGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCAGTTGAGACCAGGAGTTCGAGTCC AGCCTGACCAACATGAAGAAACCCTGTCTGTACTAAAAATCCAAAAAAAAAAAAAAAAAA AAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC014321 unedited GGGACTAGGATTTTGTNATNACGACTTTACTATAGGCGGCCGCGCAATTCGCCATTACGG CCGGGGGGAAATGCCCTGGAGTGTGTGTCACCTGTCCAGGACGACTTGTTGATTCCCAGG AGGGCCGCCTTTCCGGTCTGGGTCCCCGAGAGGACTGCCTTGCTCACCTGTCCCCTCGGC GCGGCCCCGGGGAGCTCCCGAGAGGCCCCCGGGATCGCTGGCCCTCCGAACTCCACAGCA ATGAGCAAGTTGGGCAAGTTCTTTAAAGGGGGCGGCTCTTCTAAGAGCCGAGCCGCTCCC AGTCCCCAGGAGGCCCTGGTCCGACTTCGGGAGACTGAGGAGATGCTGGGCAAGAAACAA GAGTACCTGGAAAATCGAATCCAGAGAGAAATCGCCCTGGCCAAGAAGCACGGCACGCAG AATAAGCGAGCTGCATTACAGGCACTAAAGAGAAAGAAGAGGTTCGAGAAACAGCTCACT CAGATTGATGGCACACTTTCTACCATTGAGTTCCAGAGAGAAGCCCTGGAGAACTCACAC ACCAACACTGAGGTGTTGAGGAACATGGGCTTTGCAGCAAAAGCGATGAAATCTGTTCAT GAAAACATGGATCTGAACAAAATAGATGATTTGATGCAAGAGATCACAGAGCAACAGGAT ATCGCCCAAGAGATCTCAGAAGCATTTTCTCAACGGGTTGGGCTTTGGTGATGACTTTGA TGAGGATGAGTTGATGGCAGAACTTGCAGAATTGGACAGGGGGGATTNAATAAGGAGATG ACAAATATCCGCCTGCCAAATGTGCCTTTCTCTTTTCTCCAACACAGGCAAATAGAAAAA CCAGGCATGTCGTCACTGCCCGTCAATCCCGATCAGCATTCTTCCAAAGGCCAGAGAGAA GGTTGATAAATCAAACAATTGC
Restriction Sites	Please inquire
ACCN	BC014321
Insert Size	1212 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC014321.1, AAH14321.1
RefSeq Size	1212 bp
Locus ID	92421
Protein Pathways	Endocytosis
Gene Summary	CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

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