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TGM1 (NM_000359) Human Untagged Clone
CAT＃: SC122560
TGM1 (untagged)-Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1)
CNY 5,992.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000359 edited
CTGTCCCATCCATCCTGACCTGTTCCATCTCAGCCCCAGGACTCAGTACTGCGGTTGCCA ACACTGCTGCCAGGCATGATGGATGGGCCACGTTCCGATGTGGGCCGTTGGGGTGGCAAC CCCTTGCAGCCCCCTACCACGCCATCTCCAGAGCCAGAGCCAGAGCCAGACGGACGCTCT CGCAGAGGAGGAGGCCGTTCCTTCTGGGCTCGCTGCTGTGGCTGCTGTTCATGCCGAAAT GCGGCAGATGACGACTGGGGACCTGAACCCTCTGACTCCAGGGGTCGAGGGTCCAGCTCT GGCACTCGAAGACCTGGCTCCCGGGGCTCAGACTCCCGCCGGCCTGTATCCCGGGGCAGC GGTGTCAATGCAGCTGGAGATGGCACCATCCGAGAGGGCATGCTAGTAGTGAACGGTGTG GACTTGCTGAGCTCGCGCTCGGACCAGAACCGCCGAGAGCACCACACAGACGAGTATGAG TACGACGAGCTGATAGTGCGCCGCGGGCAGCCTTTCCATATGCTCCTCCTCCTGTCCCGG ACCTATGAATCCTCTGATCGCATCACCCTTGAGTTACTCATCGGAAACAACCCCGAGGTG GGCAAGGGCACGCACGTGATCATCCCAGTGGGCAAGGGGGGCAGTGGAGGCTGGAAAGCC CAGGTGGTCAAGGCCAGTGGGCAGAATCTGAACCTGCGGGTCCACACTTCCCCCAACGCC ATCATCGGCAAGTTTCAGTTCACAGTCCGCACACAATCAGACGCTGGGGAGTTCCAGTTG CCCTTTGACCCCCGCAATGAGATCTACATCCTCTTCAACCCCTGGTGCCCAGAGGACATT GTGTACGTGGACCATGAGGATTGGCGGCAGGAGTATGTTCTTAATGAGTCTGGGAGAATT TACTACGGGACCGAAGCACAGATTGGTGAGCGGACCTGGAACTACGGCCAGTTTGACCAC GGGGTGCTGGATGCCTGCTTATACATCCTGGACCGGCGGGGGATGCCATATGGAGGCCGT GGAGACCCAGTCAATGTCTCCCGGGTCATCTCTGCCATGGTGAACTCCCTGGATGACAAT GGAGTCCTGATTGGGAACTGGTCTGGTGATTACTCCCGAGGCACCAACCCATCAGCGTGG GTGGGCAGCGTGGAGATCCTGCTTAGCTACCTACGCACGGGATATTCCGTCCCCTATGGC CAGTGCTGGGTCTTTGCTGGCGTGACCACCACAGTGCTGCGCTGCCTGGGTCTGGCCACC CGTACTGTCACCAACTTCAACTCCGCCCACGACACAGACACATCCCTTACCATGGACATC TACTTCGACGAGAACATGAAGCCCCTGGAGCACCTGAACCATGATTCTGTCTGGAACTTC CATGTGTGGAACGACTGCTGGATGAAGAGGCCGGATCTGCCCTCGGGCTTTGATGGGTGG CAGGTGGTGGATGCCACACCCCAAGAGACTAGCAGTGGCATCTTCTGCTGCGGCCCCTGC TCTGTGGAGTCCATCAAGAATGGCCTGGTCTACATGAAGTACGACACGCCTTTCATTTTT GCTGAGGTGAATAGTGACAAGGTGTACTGGCAGCGGCAGGATGATGGCAGCTTCAAGATT GTTTATGTGGAGGAGAAGGCCATCGGCACACTCATTGTCACAAAGGCCATCAGCTCCAAC ATGCGGGAGGACATCACCTACCTCTATAAGCACCCAGAAGGCTCAGACGCAGAGCGGAAG GCAGTAGAGACAGCAGCAGCCCACGGCAGCAAACCCAATGTGTATGCCAACCGGGGCTCA GCGGAGGATGTGGCCATGCAGGTGGAGGCACAGGACGCGGTGATGGGGCAGGATCTGATG GTCTCTGTGATGCTGATCAATCACAGCAGCAGCCGCCGCACAGTGAAACTGCACCTCTAC CTCTCAGTCACTTTCTATACTGGTGTCAGTGGTACCATCTTCAAGGAGACCAAGAAGGAA GTGGAGCTGGCACCAGGGGCCTCGGACCGTGTGACCATGCCAGTGGCCTACAAGGAATAC CGGCCCCATCTTGTGGACCAGGGGGCCATGCTGCTCAATGTCTCAGGCCACGTCAAGGAG AGCGGGCAGGTGCTGGCCAAGCAGCACACCTTCCGTCTGCGCACCCCAGACCTCTCCCTC ACGTTACTGGGAGCAGCAGTGGTTGGCCAGGAGTGTGAAGTACAGATTGTCTTCAAGAAC CCCCTTCCCGTCACCCTCACCAATGTCGTCTTCCGGCTCGAAGGCTCTGGGTTACAGAGG CCCAAGATCCTCAACGTTGGGGACATTGGAGGCAATGAAACAGTGACACTGCGCCAGTCG TTTGTGCCTGTGCGACCAGGCCCCCGCCAGCTCATTGCCAGCTTGGACAGCCCACAGCTC TCCCAGGTGCACGGTGTCATCCAGGTGGATGTGGCCCCAGCCCCTGGGGATGGGGGCTTC TTCTCAGACGCTGGAGGTGACAGTCACTTAGGAGAGACCATCCCTATGGCATCTCGAGGT GGAGCTTAGCCCTGTGCCAGGAGCAATGGGACTGGAGTCAGATGAGCAAGGACATTGCCC CAAGATAGGGGCACACTACAGAGCAGCTCCCCAGGAGCTCAGGTGGGGAGTCCAGGGCTC CCGGAGAGGGAGTCAGTCTTCACTTGCACTGGGGGAACAGATGCTAATAAACTGTTTTTT AATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_000359 unedited
NNNGGTTTGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCCCGGGATCTGTCCCA TCCATCCTGACCTGTTCCATCTCAGCCCCAGGACTCAGTACTGCGGTTGCCAACACTGCT GCCAGGCATGATGGATGGGCCACGTTCCGATGTGGGCCGTTGGGGTGGCAACCCCTTGCA GCCCCCTACCACGCCATCTCCAGAGCCAGAGCCAGAGCCAGACGGACGCTCTCGCAGAGG AGGAGGCCGTTCCTTCTGGGCTCGCTGCTGTGGCTGCTGTTCATGCCGAAATGCGGCAGA TGACGACTGGGGACCTGAACCCTCTGACTCCAGGGGTCGAGGGTCCAGCTCTGGCACTCG AAGACCTGGCTCCCGGGGCTCAGACTCCCGCCGGCCTGTATCCCGGGGCAGCGGTGTCAA TGCAGCTGGAGATGGCACCATCCGAGAGGGCATGCTAGTAGTGAACGGTGTGGACTTGCT GAGCTCGCGCTCGGACCAGAACCGCCGAGAGCACCACACAGACGAGTATGAGTACGACGA GCTGATAGTGCGCCGCGGGCAGCCTTTCCATATGCTCCTCCTCCTGTCCCGGACCTATGA ATCCTCTGATCGCATCACCCTTGAGTTACTCATCGGAAACAACCCCGAGGTGGGCAAGGG CACGCACGTGATCATCCCAGTGGGCAAGGGGGGCAGTGGAGGCTGGAAAGCCCAGGTGGT CAAGGCCAGTGGGCAGAATCTGAACCTGCGGGTCCACACTTCCCCCAACGCCATCATCGG GCAGTTTCAGTTCACAGTCCGCACACAATCAGACGCTGGGGAGTTCCAGTTGCCCCTTTG ACCCCGCAATGAGATCTACATCCTCTTCAACCCTGGTGCCCAGAGACATTGTGTACN |
| Restriction Sites | Please inquire |
| ACCN | NM_000359 |
| Insert Size | 2759 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000359.1, NP_000350.1 |
| RefSeq Size | 2709 bp |
| RefSeq ORF | 2454 bp |
| Locus ID | 7051 |
| UniProt ID | P22735 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 34911754
[TGM1]
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TRANSGLUTAMINASE-1 PROTECTS RENAL EPITHELIAL CELLS FROM HYDROGEN PEROXIDE-INDUCED APOPTOSIS THROUGH ACTIVATION OF STAT3 AND AKT SIGNALING PATHWAYS
,Murugavel Ponnusamy, Maoyin Pang, Pavan Kumar Annamaraju, Zhu Zhang, Rujun Gong, Y. Eugene Chin, and Shougang Zhuang,
Am J Physiol Renal Physiol, Aug 2009; 10.1152/ajprenal.00251.2009
[TGM1]
|
|
Transglutaminase-1 Regulates Renal Epithelial Cell Proliferation through Activation of Stat-3
,Zhu Zhang, Jingping Xing, Li Ma, Rujun Gong, Y. Eugene Chin, and Shougang Zhuang,
J. Biol. Chem., Jan 2009; 284: 3345 - 3353.
[TGM1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204492 | TGM1 (Myc-DDK-tagged)-Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1) |
CNY 5,984.00 |
|
| RC204492L3 | Lenti ORF clone of Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC204492L4 | Lenti ORF clone of Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1), mGFP tagged |
CNY 7,700.00 |
|
| RG204492 | TGM1 (tGFP-tagged) - Human transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) (TGM1) |
CNY 7,584.00 |
