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HNF1 beta (HNF1B) (NM_000458) Human Untagged Clone
CAT＃: SC122562
HNF1B (untagged)-Human HNF1 homeobox B (HNF1B), transcript variant 1
CNY 4,152.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADTKD3; FJHN; HNF-1-beta; HNF-1B; HNF1beta; HNF2; HPC11; LF-B3; LFB3; MODY5; RCAD; T2D; TCF-2; TCF2; VHNF1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000458 edited
ATCATGGCAAGTTAGAAGTTTTCTGACTCCTTTCGGAGGAGCCTCCGGGACCCCGGGGAG TAACAGGTGTCTGGAGGCTGAAGGGTGGAGGGGTTCCTGGATTTGGGGTTTGCTTGTGAA ACTCCCCTCCACCCTCCTCTCTCGCACCCACCCACCCCCTCACCCCCTTCTTTTTCCGTC CTTGGAAAATGGTGTCCAAGCTCACGTCGCTCCAGCAAGAACTCCTGAGCGCCCTGCTGA GCTCCGGGGTCACCAAGGAGGTGCTGGTTCAGGCCTTGGAGGAGTTGCTGCCATCCCCGA ACTTCGGGGTGAAGCTGGAGACGCTGCCCCTGTCCCCTGGCAGCGGGGCCGAGCCCGACA CCAAGCCGGTCTTCCATACTCTCACCAACGGCCACGCCAAGGGCCGCTTGTCCGGCGACG AGGGCTCCGAGGACGGCGACGACTATGACACACCTCCCATCCTCAAGGAGCTGCAGGCGC TCAACACCGAGGAGGCGGCGGAGCAGCGGGCGGAGGTGGACCGGATGCTCAGTGAGGACC CTTGGAGGGCTGCTAAAATGATCAAGGGTTACATGCAGCAACACAACATCCCCCAGAGGG AGGTGGTCGATGTCACCGGCCTGAACCAGTCGCACCTCTCCCAGCATCTCAACAAGGGCA CCCCTATGAAGACCCAGAAGCGTGCCGCTCTGTACACCTGGTACGTCAGAAAGCAACGAG AGATCCTCCGACAATTCAACCAGACAGTCCAGAGTTCTGGAAATATGACAGACAAAAGCA GTCAGGATCAGCTGCTGTTTCTCTTTCCAGAGTTCAGTCAACAGAGCCATGGGCCTGGGC AGTCCGATGATGCCTGCTCTGAGCCCACCAACAAGAAGATGCGCCGCAACCGGTTCAAAT GGGGGCCCGCGTCCCAGCAAATCTTGTACCAGGCCTACGATCGGCAAAAGAACCCCAGCA AGGAAGAGAGAGAGGCCTTAGTGGAGGAATGCAACAGGGCAGAATGTTTGCAGCGAGGGG TGTCCCCCTCCAAAGCCCACGGCCTGGGCTCCAACTTGGTCACTGAGGTCCGTGTCTACA ACTGGTTTGCAAACCGCAGGAAGGAGGAGGCATTCCGGCAAAAGCTGGCCATGGACGCCT ATAGCTCCAACCAGACTCACAGCCTGAACCCTCTGCTCTCCCACGGCTCCCCCCACCACC AGCCCAGCTCCTCTCCTCCAAACAAGCTGTCAGGAGTGCGCTACAGCCAGCAGGGAAACA ATGAGATCACTTCCTCCTCAACAATCAGTCACCATGGCAACAGCGCCATGGTGACCAGCC AGTCGGTTTTACAGCAAGTCTCCCCAGCCAGCCTGGACCCAGGCCACAATCTCCTCTCAC CTGATGGTAAAATGATCTCAGTCTCAGGAGGAGGTTTGCCCCCAGTCAGCACCTTGACGA ATATCCACAGCCTCTCCCACCATAATCCCCAGCAATCTCAAAACCTCATCATGACACCCC TCTCTGGAGTCATGGCAATTGCACAAAGCCTCAACACCTCCCAAGCACAGAGTGTCCCTG TCATCAACAGTGTGGCCGGCAGCCTGGCAGCCCTGCAGCCCGTCCAGTTCTCCCAGCAGC TGCACAGCCCTCACCAGCAGCCCCTCATGCAGCAGAGCCCAGGCAGCCACATGGCCCAGC AGCCCTTCATGGCAGCTGTGACTCAGCTGCAGAACTCACACATGTACGCACACAAGCAGG AACCCCCCCAGTATTCCCACACCTCCCGGTTTCCATCTGCAATGGTGGTCACAGATACCA GCAGCATCAGTACACTCACCAACATGTCTTCAAGTAAACAGTGTCCTCTACAAGCCTGGT GATGCCCACACACCACTTACTTCGTGCGCAACAACAAGGACCCTGTTTTCCACACCATCA CCCTCTGGGCAGCTGTCATGGAAAAGCCCAGTGACCTGACCAGCACCTGCGAGAGGTCCC TGCTTACCTGACGGACGTCCTGCTGGCACCTCAGACAATCCACTCTCAGGAGGCGCAGCC CGAAGCCCAGTTTCCCTTCTATGCAGTATTGCCACAATGCCTCTCCCACGATGTCAAGGA CTCCTGTCTGTCCTGGAGGTGGGAGACAAGGAACCTCCGAAGAGGAAGCAAGAAAGCCGT ACTGTCTATGTTGTGATCCTTCATCGAACAAACTGATGCGAAAACTTGAATCTGTTACTG AAATGAGGAGAGAAGGACATGTGCTATTGAACTGAGCCAAACACACTGTAAATATCCACA GACTCCCTCCCCTGCCCCCATCCCAAATGATCTTGAGATTTCTTTTAAAGAAGTAAATTT GTCCAATGGCTGTAAACTATAAACTACTGTAATTAAGTGCAATTTCCCCTCTGTGTCCTC TCCCCTCTGCCCTGTATATAATACTAAAGTGTCTATTAGTTTTCTTTGTAAAGGTCAGAG TCAAAATTTCAAAAGTGATCTGTCCCCTCTCCCCTCATGGAGAAACATCCTAAGTGGGAA GTGAAGCCCCTTGTCCTCTCCCGCGGGCCTGGACACTTATGGGGACAGCATACCTTGGAC TGACTACCAGCTAACTCCAGTCTCCTGACATTAAGACACACCTCTGGATCCCTGGAGGGG CTGAATGTAGTGTGTCAGAGTAACATGCCAGCTTCCTGTGGGCCAGGAGCTCAGCCGTGC ACTCCCTAAGAAACCCCAGGGCAGGGAAACTGGCTGTTTGATAGCAGAAGAAAAAGTTGC AGTCTCAGAAAGCCTTCCATTAAAACAATTTATTTTATCACTAAAAAAAAAAAAAAAA >OriGene 5' read for NM_000458 unedited
GCGGGCCGCGNAATTCCCGGGGTATCGTCGACCCACGCGTCCGATCATGGCAAGTTAGAA GTTTTCTGACTCCTTTCGGAGGAGCCTCCGGGACCCCGGGGAGTAACAGGTGTCTGGAGG CTGAAGGGTGGAGGGGTTCCTGGATTTGGGGTTTGCTTGTGAAACTCCCCTCCACCCTCC TCTCTCGCACCCACCCACCCCCTCACCCCCTTCTTTTTCCGTCCTTGGAAAATGGTGTCC AAGCTCACGTCGCTCCAGCAAGAACTCCTGAGCGCCCTGCTGAGCTCCGGGGTCACCAAG GAGGTGCTGGTTCAAGCCTTGGAGGAGTTGCTGCCATCCCCGAACTTCGGGGTGAAGCTG GAGACGCTGCCCCTGTCCCCTGGCAGCGGGGCCGAGCCCGACACCAAGCCGGTCTTCCAT ACTCTCACCAACGGCCACGCCAAGGGCCGCTTGTCCGGCGACGAGGGCTCCGAGGACGGC GACGACTATGACACACCTCCCATCCTCAAGGAGCTGCAGGCGCTCAACACCGAGGAGGCG GCGGATCATCGGGCGGAGGTGGACCGGATGCTCAGTGAGGACCCTTGGAGGGCTGCTAAA ATGATCAAGGGTTACATGCAGGCACACAACATCCCCCAGAGGGAGGTGGTCGATGTCACC GGCCTGAACCAGTCGCACCTCTCCCAGCATCTCAACCAGGGCACCCCTATGAAGACCCAT GATCGTGCCGCTCTGTACACCTGGTACGTCAGAAAGCAACGAGAGATCCTCCGACAATCA ACCAGACAGTCCAGAGTTCTGGAAATATGACAGACANAAGCAGTCAGGATCAGCTGCTGT TTCTCTTTCCGAGTTCAGTCACAGAGC |
| Restriction Sites | Please inquire |
| ACCN | NM_000458 |
| Insert Size | 2818 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000458.1, NP_000449.1 |
| RefSeq Size | 2816 bp |
| RefSeq ORF | 1674 bp |
| Locus ID | 6928 |
| UniProt ID | P35680 |
| Protein Families | Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
| Protein Pathways | Maturity onset diabetes of the young |
| Gene Summary | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs
,Simeonov, KP;Uppal, H;,
PLoS ONE
,PubMed ID 24963715
[HNF1B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204453 | HNF1B (Myc-DDK-tagged)-Human HNF1 homeobox B (HNF1B), transcript variant 1 |
CNY 4,152.00 |
|
| RC204453L1 | Lenti ORF clone of Human HNF1 homeobox B (HNF1B), transcript variant 1, Myc-DDK-tagged |
CNY 6,552.00 |
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| RC204453L2 | Lenti ORF clone of Human HNF1 homeobox B (HNF1B), transcript variant 1, mGFP tagged |
CNY 6,552.00 |
|
| RC204453L3 | Lenti ORF clone of Human HNF1 homeobox B (HNF1B), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC204453L4 | Lenti ORF clone of Human HNF1 homeobox B (HNF1B), transcript variant 1, mGFP tagged |
CNY 6,552.00 |
|
| RG204453 | HNF1B (tGFP-tagged) - Human HNF1 homeobox B (HNF1B), transcript variant 1 |
CNY 5,752.00 |
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