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HAND1 (NM_004821) Human Untagged Clone
CAT＃: SC122690
HAND1 (untagged)-Human heart and neural crest derivatives expressed 1 (HAND1)
CNY 2,400.00
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bHLHa27; eHand; Hxt; Thing1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004821 edited
GTCCGCAGAAGGGTTAAACAGGTCTTTGGGCTTCGGCGACCTCGCCCGCGGCAGAAACCG GTAAGAAGACAGTGGGCTGCGCGTCTCATTTTCAGCCTTGCCCGGACTCTCCCAAAGCCG GCGCCCAGTAGTGGCTCCAGAGCCCACAGGTGGCCCCCGGCAGTCTCTGGGGCGCATGGA GCGGCGTTAATAGGGCTGGCGGCGCAGGCCAGTAGCCGCTCCAACATGAACCTCGTGGGC AGCTACGCACACCATCACCACCATCACCACCCGCACCCTGCGCACCCCATGCTCCACGAA CCCTTCCTCTTCGGTCCGGCCTCGCGCTGTCATCAGGAAAGGCCCTACTTCCAGAGCTGG CTGCTGAGCCCGGCTGACGCTGCCCCGGACTTCCCTGCGGGCGGGCCGCCGCCCGCGGCC GCTGCAGCCGCCACCGCCTATGGTCCTGACGCCAGGCCTGGGCAGAGCCCCGGGCGGCTG GAGGCGCTTGGCGGCCGTCTTGGCCGGCGGAAAGGCTCAGGACCCAAGAAGGAGCGGAGA CGCACTGAGAGCATTAACAGCGCATTCGCGGAGTTGCGCGAGTGCATCCCCAACGTGCCG GCCGACACCAAGCTCTCCAAGATCAAGACTCTGCGCCTAGCCACCAGCTACATCGCCTAC CTGATGGACGTGCTGGCCAAGGATGCACAGTCTGGCGATCCCGAGGCCTTCAAGGCTGAA CTCAAGAAGGCGGATGGCGGCCGTGAGAGCAAGCGGAAAAGGGAGCTGCAGCAGCACGAA GGTTTTCCTCCTGCCCTGGGCCCAGTCGAGAAGAGGATTAAAGGACGCACCGGCTGGCCG CAGCAAGTCTGGGCGCTGGAGTTAAACCAGTGAGCCGAGGCCCGCGCCGAGGACCTGGCC AGGCCAGCCACTCCTGAAGCCCCGGGAGGAGAGGAAGGCAGCGGCGAACGCCAGGCTCTG GGCTCCGGCGACTGGTGCTACGCATCCCGCGGAGCTTCTGCTGAGCGCCGGCAGGTCGTC GGCTGCAACCACACACTTGGATCGCACGTGCAATGTCCTTTGATTTTTTTTAATACATTA AGAGAAAGAGAAATATATATATATCCACCCCCAGCCCAACCGAGGGCGGCCCTTGGCGGC AACATGCAAGAAGGAGGGACTGTCGAACCCAAGGGCTCAAAGACGCACTCTTCCACCCTT TTGGAGCGAATTTAGAACCTCAGCCCTATCTCCATTTCCCTATCTGGCTCTTTCTCTCTT GTCCCTCCATATGATCCGCCCCGACGCCGTCTTCTCTAATTAAAATGCAATAAGGAATCA ATTCTTTTCTGCCTGAGAAAGAGAACCAGACGCAGGAAGATGAAAGGCTGCCCTTTGTTC TTCGAATCGTGGTGGTTTTATTTTATTTTTCTTTTTGTCGCTGCACTTCCTGTTTAGTTC CAAGGGAAACACTTTCTCTCTTTCTCTGTCTCTCTCTTTTCTTCCTTCTTTTCCTTCCTT TTTGTTTCTATCTAAATAAAAGCTTTCCCTGTGTTGGAAAGTTTTTATGTATTTAAACTA CCTACCATGCCTGTTGTGCTCAGGTGTTTGTTCATCCTGCCATCCCCAACCCTTTTCTAC CTCAAGTCTGTGTGACCACTCACAGCCCCCCTCCCTTCGCCAAAGCAGTGTCTATGCTCT TGATTAATAAAACATTTTCTGAAATCAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_004821 unedited
NNAAGTTGAATTTGTATACGACTCATATAGGCGGGCCGCGAATTCGCACGAGGGGTCCGC AGAAGGGTTAAACAGGTCTTTGGGCTTCGGCGACCTCGCCCGCGGCAGAAACCGGTAAGA AGACAGTGGGCTGCGCGTCTCATTTTCAGCCTTGCCCGGACTCTCCCAAAGCCGGCGCCC AGTAGTGGCTCCAGAGCCCACAGGTGGCCCCCGGCAGTCTCTGGGGCGCATGGAGCGGCG TTAATAGGGCTGGCGGCGCAGGCCAGTAGCCGCTCCAACATGAACCTCGTGGGCAGCTAC GCACACCATCACCACCATCACCACCCGCACCCTGCGCACCCCATGCTCCACGAACCCTTC CTCTTCGGTCCGGCCTCGCGCTGTCATCAGGAAAGGCCCTACTTCCAGAGCTGGCTGCTG AGCCCGGCTGACGCTGCCCCGGACTTCCCTGCGGGCGGGCCGCCGCCCGCGGCCGCTGCA GCCGCCACCGCCTATGGTCCTGACGCCAGGCCTGGGCAGAGCCCCGGGCGGCTGGAGGCG CTTGGCGGCCGTCTTGGCCGGCGGAAAGGCTCAGGACCCAAGAAGGAGCGGAGACGCACT GAGAGCATTAACAGCGCATTCGCGGAGTTGCGCGAGTGCATCCCCAACGTGCCGGCCGAC ACCAAGCTCTCCAAGATCAAGACTCTGCGCCTAGCCACCAGCTACATCGCCTACCTGATG GACGTGCTGGCCAAGGATGCACAGTCTGGCGATCCCNGAGCCTTCAAGGCTGAACTCAAN AAAGCNGATGGCGGCCGTGAGAGCAGCCGGAAAAGGAGCTGCAGCAGCACGAAGGGTTTC CTCCTGCCCTGNGGCCCCAGTCGAGAAGAGGATTAAAGGACCCACCGGCTGGCCGCA |
| Restriction Sites | Please inquire |
| ACCN | NM_004821 |
| Insert Size | 1733 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004821.1, NP_004812.1 |
| RefSeq Size | 1750 bp |
| RefSeq ORF | 648 bp |
| Locus ID | 9421 |
| UniProt ID | O96004 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
| Gene Summary | The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome
,Kobayashi, J;Yoshida, M;Tarui, S;Hirata, M;Nagai, Y;Kasahara, S;Naruse, K;Ito, H;Sano, S;Oh, H;,
PLoS ONE July 2014
,PubMed ID 25050861
[HAND1]
|
|
MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension
,Ryan S. Friese, Angelina E. Altshuler, Kuixing Zhang, Jose Pablo Miramontes-Gonzalez, C. Makena Hightower, Martin L. Jirout, Rany M. Salem, Jiaur R. Gayen, Nitish R. Mahapatra, Nilima Biswas, Mo Cale, Sucheta M. Vaingankar, Hyung-Suk Kim, Maïté Courel, Laurent Taupenot, Michael G. Ziegler, Nicholas J. Schork, Michal Pravenec, Sushil K. Mahata, Geert W. Schmid-Schönbein, and Daniel T. O'Connor,
Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt213.
,PubMed ID 23674521
[HAND1]
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The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina
,Sacha Reichman, Ravi Kiran Reddy Kalathur, Sophie Lambard, Najate Aït-Ali, Yanjiang Yang, Aurélie Lardenois, Raymond Ripp, Olivier Poch, Donald J. Zack, José-Alain Sahel, and Thierry Léveillard,
Hum. Mol. Genet., Jan 2010; 19: 250 - 261
[HAND1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200513 | HAND1 (Myc-DDK-tagged)-Human heart and neural crest derivatives expressed 1 (HAND1) |
CNY 2,400.00 |
|
| RC200513L1 | Lenti ORF clone of Human heart and neural crest derivatives expressed 1 (HAND1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC200513L2 | Lenti ORF clone of Human heart and neural crest derivatives expressed 1 (HAND1), mGFP tagged |
CNY 4,800.00 |
|
| RC200513L3 | Lenti ORF clone of Human heart and neural crest derivatives expressed 1 (HAND1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200513L4 | Lenti ORF clone of Human heart and neural crest derivatives expressed 1 (HAND1), mGFP tagged |
CNY 5,890.00 |
|
| RG200513 | HAND1 (tGFP-tagged) - Human heart and neural crest derivatives expressed 1 (HAND1) |
CNY 4,000.00 |
