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TLR9 (NM_017442) Human Untagged Clone
CAT＃: SC122858
TLR9 (untagged)-Human toll-like receptor 9 (TLR9)
CNY 7,192.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD289 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_017442 edited
CCACGCGTCCGGGGACCTCGAGTGTGAAGCATCCTTCCCTGTAGCTGCTGTCCAGTCTGC CCGCCAGACCCTCTGGAGAAGCCCCTGCCCCCCAGCATGGGTTTCTGCCGCAGCGCCCTG CACCCGCTGTCTCTCCTGGTGCAGGCCATCATGCTGGCCATGACCCTGGCCCTGGGTACC TTGCCTGCCTTCCTACCCTGTGAGCTCCAGCCCCACGGCCTGGTGAACTGCAACTGGCTG TTCCTGAAGTCTGTGCCCCACTTCTCCATGGCAGCACCCCGTGGCAATGTCACCAGCCTT TCCTTGTCCTCCAACCGCATCCACCACCTCCATGATTCTGACTTTGCCCACCTGCCCAGC CTGCGGCATCTCAACCTCAAGTGGAACTGCCCGCCGGTTGGCCTCAGCCCCATGCACTTC CCCTGCCACATGACCATCGAGCCCAGCACCTTCTTGGCTGTGCCCACCCTGGAAGAGCTA AACCTGAGCTACAACAACATCATGACTGTGCCTGCGCTGCCCAAATCCCTCATATCCCTG TCCCTCAGCCATACCAACATCCTGATGCTAGACTCTGCCAGCCTCGCCGGCCTGCATGCC CTGCGCTTCCTATTCATGGACGGCAACTGTTATTACAAGAACCCCTGCAGGCAGGCACTG GAGGTGGCCCCGGGTGCCCTCCTTGGCCTGGGCAACCTCACCCACCTGTCACTCAAGTAC AACAACCTCACTGTGGTGCCCCGCAACCTGCCTTCCAGCCTGGAGTATCTGCTGTTGTCC TACAACCGCATCGTCAAACTGGCGCCTGAGGACCTGGCCAATCTGACCGCCCTGCGTGTG CTCGATGTGGGCGGAAATTGCCGCCGCTGCGACCACGCTCCCAACCCCTGCATGGAGTGC CCTCGTCACTTCCCCCAGCTACATCCCGATACCTTCAGCCACCTGAGCCGTCTTGAAGGC CTGGTGTTGAAGGACAGTTCTCTCTCCTGGCTGAATGCCAGTTGGTTCCGTGGGCTGGGA AACCTCCGAGTGCTGGACCTGAGTGAGAACTTCCTCTACAAATGCATCACTAAAACCAAG GCCTTCCAGGGCCTAACACAGCTGCGCAAGCTTAACCTGTCCTTCAATTACCAAAAGAGG GTGTCCTTTGCCCACCTGTCTCTGGCCCCTTCCTTCGGGAGCCTGGTCGCCCTGAAGGAG CTGGACATGCACGGCATCTTCTTCCGCTCACTCGATGAGACCACGCTCCGGCCACTGGCC CGCCTGCCCATGCTCCAGACTCTGCGTCTGCAGATGAACTTCATCAACCAGGCCCAGCTC GGCATCTTCAGGGCCTTCCCTGGCCTGCGCTACGTGGACCTGTCGGACAACCGCATCAGC GGAGCTTCGGAGCTGACAGCCACCATGGGGGAGGCAGATGGAGGGGAGAAGGTCTGGCTG CAGCCTGGGGACCTTGCTCCGGCCCCAGTGGACACTCCCAGCTCTGAAGACTTCAGGCCC AACTGCAGCACCCTCAACTTCACCTTGGATCTGTCACGGAACAACCTGGTGACCGTGCAG CCGGAGATGTTTGCCCAGCTCTCGCACCTGCAGTGCCTGCGCCTGAGCCACAACTGCATC TCGCAGGCAGTCAATGGCTCCCAGTTCCTGCCGCTGACCGGTCTGCAGGTGCTAGACCTG TCCCACAATAAGCTGGACCTCTACCACGAGCACTCATTCACGGAGCTACCACGACTGGAG GCCCTGGACCTCAGCTACAACAGCCAGCCCTTTGGCATGCAGGGCGTGGGCCACAACTTC AGCTTCGTGGCTCACCTGCGCACCCTGCGCCACCTCAGCCTGGCCCACAACAACATCCAC AGCCAAGTGTCCCAGCAGCTCTGCAGTACGTCGCTGCGGGCCCTGGACTTCAGCGGCAAT GCACTGGGCCATATGTGGGCCGAGGGAGACCTCTATCTGCACTTCTTCCAAGGCCTGAGC GGTTTGATCTGGCTGGACTTGTCCCAGAACCGCCTGCACACCCTCCTGCCCCAAACCCTG CGCAACCTCCCCAAGAGCCTACAGGTGCTGCGTCTCCGTGACAATTACCTGGCCTTCTTT AAGTGGTGGAGCCTCCACTTCCTGCCCAAACTGGAAGTCCTCGACCTGGCAGGAAACCAG CTGAAGGCCCTGACCAATGGCAGCCTGCCTGCTGGCACCCGGCTCCGGAGGCTGGATGTC AGCTGCAACAGCATCAGCTTCGTGGCCCCCGGCTTCTTTTCCAAGGCCAAGGAGCTGCGA GAGCTCAACCTTAGCGCCAACGCCCTCAAGACAGTGGACCACTCCTGGTTTGGGCCCCTG GCGAGTGCCCTGCAAATACTAGATGTAAGCGCCAACCCTCTGCACTGCGCCTGTGGGGCG GCCTTTATGGACTTCCTGCTGGAGGTGCAGGCTGCCGTGCCCGGTCTGCCCAGCCGGGTG AAGTGTGGCAGTCCGGGCCAGCTCCAGGGCCTCAGCATCTTTGCACAGGACCTGCGCCTC TGCCTGGATGAGGCCCTCTCCTGGGACTGTTTCGCCCTCTCGCTGCTGGCTGTGGCTCTG GGCCTGGGTGTGCCCATGCTGCATCACCTCTGTGGCTGGGACCTCTGGTACTGCTTCCAC CTGTGCCTGGCCTGGCTTCCCTGGCGGGGGCGGCAAAGTGGGCGAGATGAGGATGCCCTG CCCTACGATGCCTTCGTGGTCTTCGACAAAACGCAGAGCGCAGTGGCAGACTGGGTGTAC AACGAGCTTCGGGGGCAGCTGGAGGAGTGCCGTGGGCGCTGGGCACTCCGCCTGTGCCTG GAGGAACGCGACTGGCTGCCTGGCAAAACCCTCTTTGAGAACCTGTGGGCCTCGGTCTAT GGCAGCCGCAAGACGCTGTTTGTGCTGGCCCACACGGACCGGGTCAGTGGTCTCTTGCGC GCCAGCTTCCTGCTGGCCCAGCAGCGCCTGCTGGAGGACCGCAAGGACGTCGTGGTGCTG GTGATCCTGAGCCCTGACGGCCGCCGCTCCCGCTACGTGCGGCTGCGCCAGCGCCTCTGC CGCCAGAGTGTCCTCCTCTGGCCCCACCAGCCCAGTGGTCAGCGCAGCTTCTGGGCCCAG CTGGGCATGGCCCTGACCAGGGACAACCACCACTTCTATAACCGGAACTTCTGCCAGGGA CCCACGGCCGAATAGCCGTGAGCCGGAATCCTGCACGGTGCCACCTCCACACTCACCTCA CCTCTGCCTGCCTGGTCTGACCCTCCCCTGCTCGCCTCCCTCACCCCACACCTGACACAG AGCAGGCACTCAATAAATGCTACCGAAGGCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_017442 unedited
NNNNAAAGTTCAGATTTTGTAATACGACTTCACTATAGGGCGGGCCGCGCAATTCCCGGG GTATCGTCGACCCACGCGTCCGGGGACCTCGAGTGTGAAGCATCCTTCCCTGTAGCTGCT GTCCAGTCTGCCCGCCAGACCCTCTGGAGAAGCCCCTGCCCCCCAGCATGGGTTTCTGCC GCAGCGCCCTGCACCCGCTGTCTCTCCTGGTGCAGGCCATCATGCTGGCCATGACCCTGG CCCTGGGTACCTTGCCTGCCTTCCTACCCTGTGAGCTCCAGCCCCACGGCCTGGTGAACT GCAACTGGCTGTTCCTGAAGTCTGTGCCCCACTTCTCCATGGCAGCACCCCGTGGCAATG TCACCAGCCTTTCCTTGTCCTCCAACCGCATCCACCACCTCCATGATTCTGACTTTGCCC ACCTGCCCAGCCTGCGGCATCTCAACCTCAAGTGGAACTGCCCGCCGGTTGGCCTCAGCC CCATGCACTTCCCCTGCCACATGACCATCGAGCCCAGCACCTTCTTGGCTGTGCCCACCC TGGAAGAGCTAAACCTGAGCTACAACAACATCATGACTGTGCCTGCGCTGCCCAAATCCC TCATATCCCTGTCCCTCAGCCATACCAACATCCTGATGCTAGACTCTGCCAGCCTCGCCG GCCTGCATGCCCTGCGCTTCCTATTCATGGACGGCAACTGTTATTACAAGAACCCCTGCA GGCAGGCACTGGAGGTGGCCCCGGGTGCCCCTCTTGGCCTGGGGCACCTCACCCACCTGT CACTCAAGTACAACAACCTCACTGTGGTGCCCCGGCACCTGCCCTTCAGCCCTGGAGTAT CTGCTGGTTGTCCTACAACCGCATCGTTCAACTGGGCGCCTGAGGACCTTGGCCAATCTG ACCGC |
| Restriction Sites | Please inquire |
| ACCN | NM_017442 |
| Insert Size | 3384 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017442.2, NP_059138.1 |
| RefSeq Size | 3868 bp |
| RefSeq ORF | 3099 bp |
| Locus ID | 54106 |
| UniProt ID | Q9NR96 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Toll-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (A) is a biexonic transcript which encodes the longer isoform (A). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
,H D Park, Y Lee, Y K Oh, J G Jung, Y W Park, K Myung, K-H Kim, S S Koh, D-S Lim,
Oncogene (30 August 2010) doi:10.1038/onc.2010.401 Original Article
[TLR9]
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