Claudin 6 (CLDN6) (NM_021195) Human Untagged Clone

CAT#: SC122907

CLDN6 (untagged)-Human claudin 6 (CLDN6)



  "NM_021195" in other vectors (6)

CNY 3,600.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
CLDN6 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_021195 edited
ATCTCCTTCGCAGTGCAGCTCCTTCAACCTCGCCATGGCCTCTGCCGGAATGCAGATCCT
GGGAGTCGTCCTGACACTGCTGGGCTGGGTGAATGGCCTGGTCTCCTGTGCCCTGCCCAT
GTGGAAGGTGACCGCTTTCATCGGCAACAGCATCGTGGTGGCCCAGGTGGTGTGGGAGGG
CCTGTGGATGTCCTGCGTGGTGCAGAGCACCGGCCAGATGCAGTGCAAGGTGTACGACTC
ACTGCTGGCGCTGCCACAGGACCTGCAGGCTGCACGTGCCCTCTGTGTCATCGCCCTCCT
TGTGGCCCTGTTCGGCTTGCTGGTCTACCTTGCTGGGGCCAAGTGTACCACCTGTGTGGA
GGAGAAGGATTCCAAGGCCCGCCTGGTGCTCACCTCTGGGATTGTCTTTGTCATCTCAGG
GGTCCTGACGCTAATCCCCGTGTGCTGGACGGCGCATGCCGTCATCCGGGACTTCTATAA
CCCCCTGGTGGCTGAGGCCCAAAAGCGGGAGCTGGGGGCCTCCCTCTACTTGGGCTGGGC
GGCCTCAGGCCTTTTGTTGCTGGGTGGGGGGTTGCTGTGCTGCACTTGCCCCTCGGGGGG
GTCCCAGGGCCCCAGCCATTACATGGCCCGCTACTCAACATCTGCCCCTGCCATCTCTCG
GGGGCCCTCTGAGTACCCTACCAAGAATTACGTCTGACGTGGAGGGGAATGGGGGCTCCG
CTGGCGCTAGAGCCATCCAGAAGTGGCAGTGCCCAACAGCTTTGGGATGGGTTCGTACCT
TTTGTTTCTGCCTCCTGCTATTTTTCTTTTGACTGAGGATATTTAAAATTCATTTGAAAA
CTGAGCCAAGGTGTTGACTCAGACTCTCACTTAGGCTCTGCTGTTTCTCACCCTTGGATG
ATGGAGCCAAAGAGGGGATGCTTTGAGATTCTGGATCTTGACATGCCCATCTTAGAAGCC
AGTCAAGCTATGGAACTAATGCGGAGGCTGCTTGCTGTGCTGGCTTTGCAACAAGACAGA
CTGTCCCCAAGAGTTCCTGCTGCTGCTGGGGGCTGGGCTTCCCTAGATGTCACTGGACAG
CTGCCCCCCATCCTACTCAGGTCTCTGGAGCTCCTCTCTTCACCCCTGGAAAAACAAATG
ATCTGTTAACAAAGGACTGCCCACCTCCGGAACTTCTGACCTCTGTTTCCTCCGTCCTGA
TAAGACGTCCACCCCCCAGGGCCAGGTCCCAGCTATGTAGACCCCCGCCCCCACCTCCAA
CACTGCACCCTTCTGCCCTGCCCCCCTCGTCTCACCCCCTTTACACTCACATTTTTATCA
AATAAAGCATGTTTTGTTAGTGCAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_021195 unedited
TTTCCGTCAAGATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGNATCT
CCTTCGCAGTGCAGCTCCTTCAACCTCGCCATGGCCTCTGCCGGAATGCAGATCCTGGGA
GTCGTCCTGACACTGCTGGGCTGGGTGAATGGCCTGGTCTCCTGTGCCCTGCCCATGTGG
AAGGTGACCGCTTTCATCGGCAACAGCATCGTGGTGGCCCAGGTGGTGTGGGAGGGCCTG
TGGATGTCCTGCGTGGTGCAGAGCACCGGCCAGATGCAGTGCAAGGTGTACGACTCACTG
CTGGCGCTGCCACAGGACCTGCAGGCTGCACGTGCCCTCTGTGTCATCGCCCTCCTTGTG
GCCCTGTTCGGCTTGCTGGTCTACCTTGCTGGGGCCAAGTGTACCACCTGTGTGGAGGAG
AAGGATTCCAAGGCCCGCCTGGTGCTCACCTCTGGGATTGTCTTTGTCATCTCAGGGGTC
CTGACGCTAATCCCCGTGTGCTGGACGGCGCATGCCGTCATCCGGGACTTCTATAACCCC
CTGGTGGCTGAGGCCCAAAAGCGGGAGCTGGGGGCCTCCCTCTACTTGGGCTGGGCGGCC
TCAGGCCTTTTGTTGCTGGGTGGGGGGGGTTGCTGTGCTGCACTTGCCCCTCGGGGGGGT
CCCAGGGCCCCAGCCATTACATGGCCCGCTACTCAACATCTGCCCCTGCCATCTCTCGGG
GGCCCTCTGAGTACCCTACCAAGAATTACGTCTGACGTGGAGGGGAAATGGGGGGCTCCC
GCTGGCGCTAGAGCCATCCAGAAGTGGCAGTGCCCAACAGCTTTGGGATGGGTTTCGTAC
CTTTTGTTTCTGCCCCTGCTATTTTTCTTTTGACTGAAGATATTTAAAATCATA
Restriction Sites Please inquire     
ACCN NM_021195
Insert Size 1372 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_021195.3, NP_067018.1
RefSeq Size 1363 bp
RefSeq ORF 663 bp
Locus ID 9074
UniProt ID P56747
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Gene Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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