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LIN7 (LIN7B) (NM_022165) Human Untagged Clone
CAT＃: SC122930
LIN7B (untagged)-Human lin-7 homolog B (C. elegans) (LIN7B)
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LIN-7B; MALS-2; MALS2; VELI2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_022165 edited
GGCGGCTGTGGCGCCGACATGGCTGCGCTGGTGGAGCCGCTGGGGCTGGAGCGGGACGTG TCCCGGGCGGTTGAGCTCCTCGAGCGGCTCCAGCGCAGCGGGGAGCTGCCGCCGCAGAAG CTGCAGGCCCTCCAGCGAGTTCTGCAGAGCCGCTTCTGCTCCGCTATCCGAGAGGTGTAT GAGCAGCTTTATGACACGCTGGACATCACCGGCAGCGCCGAGATCCGAGCCCATGCCACA GCCAAGGCCACAGTGGCTGCCTTCACAGCCAGCGAGGGCCACGCACATCCCAGGGTAGTG GAGCTACCCAAGACGGATGAGGGCCTAGGCTTCAACATCATGGGTGGCAAAGAGCAAAAC TCGCCCATCTACATCTCCCGGGTCATCCCAGGGGGTGTGGCTGACCGCCATGGAGGCCTC AAGCGTGGGGATCAACTGTTGTCGGTGAACGGTGTGAGCGTTGAGGGTGAGCAGCATGAG AAGGCGGTGGAGCTGCTGAAGGCGGCCCAGGGCTCGGTGAAGCTGGTTGTCCGTTACACA CCGCGAGTGCTGGAGGAGATGGAGGCCCGGTTCGAGAAGATGCGCTCTGCCCGCCGGCGC CAACAGCATCAGAGCTACTCGTCCTTGGAGTCTCGAGGTTGAAACCACAGATCTGGACGT TCACGTGCACTCTCTTCCTGTACAGTATTTATTGTTCCTGGCACTTTATTTAAAGATATT TGACCCTCAAAAAAAAAAAAAAAA >OriGene 5' read for NM_022165 unedited
GCTCANCATTTGTNATACGACTTACTATAGGGCGGCCGCATAACTTCGTATAGCATACAT TATACGAAGTTATGGATCAAGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGGCGG CTGTGGCGCCGACATGGCTGCGCTGGTGGAGCCGCTGGGGCTGGAGCGGGACGTGTCCCG GGCGGTTGAGCTCCTCGAGCGGCTCCAGCGCAGCGGGGAGCTGCCGCCGCAGAAGCTGCA TGCCCTCCAGCGAGTTCTGCAGAGCCGCTTCTGCTCCGCTATCCGAGAGGTGTATGAGCA GCTTTATGACACGCTGGACATCACCGGCAGCGCCGAGATCCGAGCCCATGCCACAGCCAA GGCCACAGTGGCTGCCTTCACAGCCAGCGAGGGCCACGCACATCCCAGGGTAGTGGAGCT ACCCAAGACGGATGAGGGCCTAGGCTTCAACATCATGGGTGGCAAAGAGCAAAACTCGCC CATCTACATCTCCCGGGTCATCCCAAGGGGTGTGGCTGACCGCCATGGAGGCCTCAAGCG TGGGGATCAACTGTTGTCGGTGAACGGTGTGAGCGTTGAGGGTGAGCAGCATGAGAGGGC GGTGGAGCTGCTGAAGGCGGCCCCAAGGCTCGGTGAAACTGTTTGGCCGTTACCCACCCC GAGTGCTGGAGGAAAATGAAGCCCAGGTCCGAGAAGATCCCCTCTGCCCCGCCGGGGCCA AACGGCTTCAGAACCACTTCGTGCCTTGGAGTCTCGAGGGTGGAAACCCCAAGATCTGGG ACGGGCAACGTGCACTCTCCTTCCTGGGAAAGATTTTTATTGGTTCCCGGGCCCCTTTAT TATAAGAAATCTGGACCCCAAGAATAAAAAAAAAAACTCTCCAACCCTGGATCCCGCCCT AAGGGCCCTTGTCCTTCAGGGGGGGCCCGGGCCCATTTTGAGCTTGGGAACCTTAGAN |
| Restriction Sites | Please inquire |
| ACCN | NM_022165 |
| Insert Size | 749 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022165.2, NP_071448.1 |
| RefSeq Size | 755 bp |
| RefSeq ORF | 624 bp |
| Locus ID | 64130 |
| UniProt ID | Q9HAP6 |
| Protein Families | Druggable Genome |
| Gene Summary | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205598 | LIN7B (Myc-DDK-tagged)-Human lin-7 homolog B (C. elegans) (LIN7B) |
CNY 2,400.00 |
|
| RC205598L3 | Lenti ORF clone of Human lin-7 homolog B (C. elegans) (LIN7B), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205598L4 | Lenti ORF clone of Human lin-7 homolog B (C. elegans) (LIN7B), mGFP tagged |
CNY 5,890.00 |
|
| RG205598 | LIN7B (tGFP-tagged) - Human lin-7 homolog B (C. elegans) (LIN7B) |
CNY 4,000.00 |
