DENND1B (NM_144977) Human Untagged Clone
CAT#: SC123195
DENND1B (untagged)-Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2
CNY 7,220.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | C1ORF18; C1orf218; FAM31B |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_144977 edited
GGTGGGGGCCGGACGGACAGCCCCACACCGACATGTAACCATGGACTGCAGGACCAAGGC AAATCCAGACAGAACCTTTGACTTGGTGTTGAAAGTGAAATGTCATGCCTCTGAAAATGA AGAGGACAGTCCAGCTTATCTGCCGAGGATTCCCCCTGGAAAAGTACGCCGATTCGCATT TTGCATTAAGAAACTGGAAAACTTTCCTGTCGGTCCTGGCGTAGCGCCTCCCGTGTCCGG GGTAGACCTTGTACCGGCTGAAACCGCATAGCTCGACCTTCATGGCGGCAGCTCCACGGG AGGAGAAAAGATGGCCCCAACCTGTATTTTCGAATCCTGTGGTATTGTGGAAATTCCCAG AGGACTTTGGAGACCAGGAAATACTACAGAGTGTGCCAAAGTTCTGTTTTCCCTTTGACG TTGAAAGGGTGTCTCAGAATCAAGTTGGACAGCACTTTACCTTTGTACTGACAGACATTG AAAGTAAACAGAGATTTGGATTCTGCAGACTGACGTCAGGAGGCACAATTTGTTTATGCA TCCTTAGTTACCTTCCCTGGTTTGAAGTGTATTACAAGCTTCTAAATACTCTTGCAGATT ACTTGGCTAAGGAACTGGAAAATGATTTGAATGAAACTCTCAGATCACTGTATAACCACC CAGTACCAAAGGCAAATACTCCTGTAAATTTGAGTGTGCATTCCTACTTCATTGCCCCTG ATGTAACTGGACTCCCAACAATACCCGAGAGTAGAAATCTTACAGAATATTTTGTTGCCG TGGATGTGAACAACATGCTGCAGCTGTATGCCAGTATGCTGCATGAAAGGCGCATCGTGA TTATCTCGAGCAAATTAAGCACTTTAACTGCCTGTATCCATGGATCAGCTGCTCTTCTAT ACCCAATGTATTGGCAACACATATACATCCCAGTGCTTCCTCCACACCTGCTGGACTACT GCTGTGCCCCAATGCCATACCTGATTGGAATACACTCCAGCCTCATAGAGAGAGTGAAAA ACAAATCATTGGAAGATGTTGTTATGTTAAATGTTGATACAAACACATTAGAATCACCAT TTAGTGACTTGAACAACCTACCAAGTGATGTGGTCTCGGCCTTGAAAAATAAACTGAAGA AGCAGTCTACAGCTACGGGTGATGGAGTAGCTAGGGCCTTTCTTAGAGCACAGGCTGCTT TGTTTGGATACTACAGAGATGCACTGAGATACAAACCTGGTGAGCCCATCACTTTCTGTG AGGAGAGTTTTGTAAAGCACCGCTCAAGCGTGATGAAACAGTTCCTGGAAACTGCCATTA ACCTCCAGCTTTTTAAGCAGTTTATCGATGGTCGACTGGCAAAACTAAATGCAGGAAGGG GTTTCTCTGATGTATTTGAAGAAGAGATCACTTCAGGTGGCTTTTGTGGAGGTAAAGACA AGTTACAATATGATTATCCATTTTCTCAATAACAATTTTCTTGGTCTTTGCACTTGTGTC TGATAAAACCTATTTCATAAACAACTAATGATTTCCTCCTAAATATGTAATGTCTTAAAT ACATTTTTCATCTTATAAAAGCTATGGAATTAGCTTATTTTGCCTGATACCTGTTACTCA AGGCATTAAGTTGGCCTCCTGAATTGGCAGCTGTTGGCCTCGATAATCTCTTAATATTGC TGGAAATTAGTAATACAGAAATCCAGTCAACTCATATCTTCCTGTCTTTCCTTCTGAATA GTAGTATTCTCTGCTAGAAAACTACTAGTGATGGTTATTACTGAGTATGAATTTAAGAAC TGAGGTTATGATTGGTAATACAATCCAAAAAGAAGGGTCTGAACACCAAAATTCTTTATA CATATTTAAGTAACTGTATTATTATTATACAGATGTCTTTACCTTTTTGACTTTATAGAT CACTGCAGCATTAAGAAAGTTTCCAGTTTACCATTCCATAAGTACAATTAATCCTTCTAG TGTAAATGTTCAAATACTGTTATAATTATCTAGGCAATTAATAATTTACAAACTGATATT TTTGCACGATTGTAGTGGTGTATAGTCTTGACTTGCAGAGCATTTTGCTTGAGTCCTTGA AATGTCGTGTTCATTCATTATTTGCTGAGTGCTTACAATGTATTAGGCACTGTTCTAAAT ATTAAGTGTACTAAATAAACAAAAATCCTTGTATTCTGAAAAAAAAAAAAAAA >OriGene 5' read for NM_144977 unedited
GGTTGACACAAACTGGCATTTGTTAGCGCCACATACTTGATAGGGCGGCAAGCACAACTT CGTATAGCATACATTATACTAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGT CGAGAGCGGGGTGGGGGCCGGACGGACAGCCCCACACCGACATGTAACCATGGACTGCAG GACCAAGGCAAATCCAGACAGAACCTTTGACTTGGTGTTGAAAGTGAAATGTCATGCCTC TGAAAATGAAGAGGACAGTGCGGCTTATCTGCCGAGGATTCCCCCTGGAAAAGTACGCCG ATTCGCATTTTGCATTAAGAAACTGGAAAACTTTCCTGTCGGTCCTGGCGTAGCGCCTCC CGTGTCCGGGGTAGACCTTGTACCGGCTGAAACCGCATAGCTCGACCTTCATGGCGGCAG CTCCACGGGAGGAGAAAAGATGGCCCCAACCTGTATTTTCGAATCCTGTGGTATTGTGGA AATTCCCAGAGGACTTTGGAGACCAGGAAATACTACAGAGTGTGCCAAAGTTCTGTTTTC CCTTTGACGTTGAAAGGGTGTCTCAGAATCAAGTTGGACAGCACTTTACCTTTGTACTGA CAGACATTGAAAGTAAACAGAGATTTGGATTCTGCAGACTGACGTCAGGAGGCACAATTT GTTTATGCATCCTTAGTTACCTTCCCTGGTTTGAAGTGTATTACAAGCTTCTAAATACTC TTGCAGATTACTTGGCTAAGGAACTGGAAAATGATTTGAATGAAACTCTCAGATCACTGT ATAACCACCCAGTACCAAAGGCAAATACTCCTGTAAATTTGAGTGTGCATTCCTACTTCA TTGCCCCTGATGTAACTGGACTCCCAACATACCCGAGAGTAGAAATCTTACAGAATATTT TGTTGCCG |
Restriction Sites | Please inquire |
ACCN | NM_144977 |
Insert Size | 2213 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_144977.1, NP_659414.1 |
RefSeq Size | 2380 bp |
RefSeq ORF | 1191 bp |
Locus ID | 163486 |
UniProt ID | Q6P3S1 |
Protein Families | Transmembrane |
Gene Summary | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 3. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 3. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC205585 | DENND1B (Myc-DDK-tagged)-Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2 |
CNY 3,656.00 |
|
RC205585L1 | Lenti ORF clone of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC205585L2 | Lenti ORF clone of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RC205585L3 | Lenti ORF clone of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC205585L4 | Lenti ORF clone of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RC229214 | DENND1B (Myc-DDK-tagged)-Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2 |
CNY 3,990.00 |
|
RC229214L3 | Lenti ORF clone of Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RG205585 | DENND1B (tGFP-tagged) - Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2 |
CNY 5,256.00 |
|
RG229214 | DENND1B (tGFP-tagged) - Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2 |
CNY 5,624.00 |
|
SC327849 | DENND1B (untagged)-Human DENN/MADD domain containing 1B (DENND1B) transcript variant 2 |
CNY 7,220.00 |
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