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CCR3 (NM_178329) Human Untagged Clone
CAT＃: SC123356
CCR3 (untagged)-Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2
CNY 3,656.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CC-CKR-3; C C CKR3; CD193; CKR 3; CKR3; CMKBR3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_178329 edited
TGCTGGGCGAATCCCTTTCTTGTCTGGTTCATTTGGACCCTCCAAAGCCCACAGGCTGGA ACGGCTGAGTCATCCAAACAAAAAAGGTGGCAGCCCATCCCTCCCCCAGGAGCTCTACCC TGTCTCAAGTAGGTGCTACCCTGTTGCTGGTGGCTGGCTGGAATTCCAAGCCAGTTGATC TTATCCTGTGAGGTCCCTTGGAAGTGGGGCCCACAGACTGACGCTGCTCTGCTTCCTGGA TTCAGCCCTCTTCCTAAGGAGCTCATGGACCCTGGCCGTCATCAGGTTCAACCTCATATT CAACTGCTGGGCCTTGTCTTCTGGCCACACACTCTCTCCAAATCAGCGATGGTGGGGAAC TGAGGAGCCAGAGGCCATTGTGGAAGAACTCCAAGAAAACAATCTCCAGGTTATCACATC TAAAGCCTGAGCAAGATTTGAGGCTGGGAAGAGGTGGATCCCAGAATTGGAAGAAGGAGT GGTGATGCCTAAGCTATCACTGGACATATCAAGGACTTCACTAAATTAGCAGGGAGAAGT GAAATGACAACCTCACTAGATACAGTTGAGACCTTTGGTACCACATCCTACTATGATGAC GTGGGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGCCCAGTTTGTGCCCCCG CTGTACTCCCTGGTGTTCACTGTGGGCCTCTTGGGCAATGTGGTGGTGGTGATGATCCTC ATAAAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTCAACCTGGCCATTTCG GACCTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTCAGGGGGCATAACTGG GTTTTTGGCCATGGCATGTGTAAGCTCCTCTCAGGGTTTTATCACACAGGCTTGTACAGC GAGATCTTTTTCATAATCCTGCTGACAATCGACAGGTACCTGGCCATTGTCCATGCTGTG TTTGCCCTTCGAGCCCGGACTGTCACTTTTGGTGTCATCACCAGCATCGTCACCTGGGGC CTGGCAGTGCTAGCAGCTCTTCCTGAATTTATCTTCTATGAGACTGAAGAGTTGTTTGAA GAGACTCTTTGCAGTGCTCTTTACCCAGAGGATACAGTATATAGCTGGAGGCATTTCCAC ACTCTGAGAATGACCATCTTCTGTCTCGTTCTCCCTCTGCTCGTTATGGCCATCTGCTAC ACAGGAATCATCAAAACGCTGCTGAGGTGCCCCAGTAAAAAAAAGTACAAGGCCATCCGG CTCATTTTTGTCATCATGGCGGTGTTTTTCATTTTCTGGACACCCTACAATGTGGCTATC CTTCTCTCTTCCTATCAATCCATCTTATTTGGAAATGACTGTGAGCGGAGCAAGCATCTG GACCTGGTCATGCTGGTGACAGAGGTGATCGCCTACTCCCACTGCTGCATGAACCCGGTG ATCTACGCCTTTGTTGGAGAGAGGTTCCGGAAGTACCTGCGCCACTTCTTCCACAGGCAC TTGCTCATGCACCTGGGCAGATACATCCCATTCCTTCCTAGTGAGAAGCTGGAAAGAACC AGCTCTGTCTCTCCATCCACAGCAGAGCCGGAACTCTCTATTGTGTTTTAGGTCAGATGC AGAAAATTGCCTAAAGAGGAAGGACCAAGGAGATGAAGCAAACACATTAAGCCTTCCACA CTCACCTCTAAAACAGTCCTTCAAACTTCCAGTGCAACACTGAAGCTCTTGAAGACACTG AAATATACACACAGCAGTAGCAGTAGATGCATGTACCCTAAGGTCATTACCACAGGCCAG GGGCTGGGCAGCGTACTCATCATCAACCCTAAAAAGCAGAGCTTTGCTTCTCTCTCTAAA ATGAGTTACCTACATTTTAATGCACCTGAATGTTAGATAGTTACTATATGCCGCTACAAA AAGGTAAAACTTTTTATATTTTATACATTAACTTCAGCCAGCTATTGATATAAATAAAAC ATTTTCACACAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_178329 unedited
GGGGACGTTTGGATTTTGTAATACGACTTACTATAGGGNNCGGCCGCGCAATTCCAAGCC AGTTGATCTTATCCTGTGAGGTCCCTTGGAAGTGGGGCCCACAGACTGACGCTGCTCTGC TTCCTGGATTCAGCCCTCTTCCTAAGGAGCTCATGGACCCTGGCCGTCATCAGGTTCAAC CTCATATTCAACTGCTGGGCCTTGTCTTCTGGCCACACACTCTCTCCAAATCAGCGATGG TGGGGAACTGAGGAGCCAGAGGCCATTGTGGAAGAACTCCAAGAAAACAATCTCCAGGTT ATCACATCTAAAGCCTGAGCAAGATTTGAGGCTGGGAAGAGGTGGATCCCAGAATTGGAA GAAGGAGTGGTGATGCCTAAGCTATCACTGGACATATCAAGGACTTCACTAAATTAGCAG GGAGAAGTGAAATGACAACCTCACTAGATACAGTTGAGACCTTTGGTACCACATCCTACT ATGATGACGTGGGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGCCCAGTTTG TGCCCCCGCTGTACTCCCTGGTGTTCACTGTGGGCCTCTTNGGCAATGTGGTGGTGGTGA TGATCCTCATAAAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTCAACCTGG CCATTTCGGACCTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTCAGGGGGC ATAACTGGGTTTTTGGCCATGGCATGTGTAAGCTCCTCTCAAGGTTTATCACACAGGCTT GTACAGCGAGATCCTTTTTCATATCCTGCTGACAATCGACAGGTACCTGGCCATTTGTCA TGCTGTGTTTGCCCTTCAAGCCCGACTGTCACTTTTGGTGTCATCACCAGCATCTTCACC TGG |
| Restriction Sites | Please inquire |
| ACCN | NM_178329 |
| Insert Size | 2030 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_178329.1, NP_847899.1 |
| RefSeq Size | 1866 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 1232 |
| UniProt ID | P51677 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] Transcript Variant: This variant (2) lacks an internal exon in the 5' UTR, as compared to variant 1. Both variants encode the same isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8
,PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, TW Schwartz, and MM Rosenkilde,
Mol Pharmacol. 2007 Aug;72(2):327-40.
[CCR3]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223725 | CCR3 (Myc-DDK-tagged)-Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2 |
CNY 3,656.00 |
|
| RC223725L1 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC223725L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC223725L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223725L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG223725 | CCR3 (tGFP-tagged) - Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 2 |
CNY 4,370.00 |
