TRF2 (TERF2) (BC024890) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	TRBF2; TRF2
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC024890 edited ATGGCCGCGGGAGCCGGGACGGCGGGCCCCGCTTCCGGCCCGGGCGTCGTGCGTGACCCA GCGGCGTCACAGCCGAGGAAGCGGCCCGGCCGGGAGGGCGGGGAGGGCGCGCGGCGATCG GACACGATGGCGGGAGGAGGCGGGAGTAGCGACGGCAGCGGGCGGGCAGCTGGCAGGCGG GCGTCCCGCAGTAGCGGGCGGGCCCGGCGGGGGCGCCACGAGCCGGGGCTGGGGGGCCCG GCGGAGCGCGGCGCGGGGGAGGCACGGCTGGAAGAGGCAGTCAATCGCTGGGTGCTCAAG TTCTACTTCCACGAGGCGCTGCGGGCCTTTCGGGGTAGCCGGTACGGGGACTTCAGACAG ATCCGGGACATCATGCAGGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCC CGATTGCTGCGGGTTATGCAGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGT TCCTTTGATATGGAGGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATG ATTAAAACGGAATTTACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAG GAAGCTGCTGTCATTATTTGTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTG AAAAAACATATGTCCAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATT ATTCGAGAAAAGAACTTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAG CAGAAGATGCTGCGCTTCCTGGAGAGCCACCTGGATGACGCCGAGCCCTACCTCCTCACG GTGCGCCTTGGCCCTTCTCCCATAACCATGGTGTGCCCTTGAGGATGTGCGGGGAATCAG AATATCTGAAGTGAAAAGAGTTGATGTGTGAAAAAGACATTGAATTGTATGCACTAGCTT TCTTAATTAAATGCCTTAAAAATGCAAAAGCAGGCCAGGCGCAATGGCTCACGCCTGTAA TCCCAGCACTTTGGGAGGCCCAGGGGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCTG CCTGAGCAACATGGTGAAACCCCATCTCTACTAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC024890 unedited GGGNCGGACCGCGCAATTCCCGGGATATCGTCGACCCACGCGTCCGATGGCCGCGGGAGC CGGGACGGCGGGCCCCGCTTCCGGCCCGGGCGTCGTGCGTGACCCAGCGGCGTCACAGCC GAGGAAGCGGCCCGGCCGGGAGGGCGGGGAGGGCGCGCGGCGATCGGACACGATGGCGGG AGGAGGCGGGAGTAGCGACGGCAGCGGGCGGGCAGCTGGCAGGCGGGCGTCCCGCAGTAG CGGGCGGGCCCGGCGGGGGCGCCACGAGCCGGGGCTGGGGGGCCCGGCGGAGCGCGGCGC GGGGGAGGCACGGCTGGAAGAGGCAGTCAATCGCTGGGTGCTCAAGTTCTACTTCCACGA GGCGCTGCGGGCCTTTCGGGGTAGCCGGTACGGGGACTTCAGACAGATCCGGGACATCAT GCAGGCTTTGCTTGTCAGGCCCTTGGGGAAGGAGCACACCGTGTCCCGATTGCTGCGGGT TATGCAGTGTCTGTCGCGGATTGAAGAAGGGGAAAATTTAGACTGTTCCTTTGATATGGA GGCTGAGCTCACACCACTGGAATCAGCTATCAATGTGCTGGAGATGATTAAAACGGAATT TACACTGACAGAAGCAGTGGTCGAATCCAGTAGAAAACTGGTCAAGGAAGCTGCTGTCAT TATTTGTATCAAAAACAAAGAATTTGAAAAGGCTTCAAAAATTTTGAAAAAACATATGTC CAAGGACCCCACAACTCAGAAGCTGAGAAATGATCTCCTGAATATTATTCGAGAAAAGAC TTGGCCCATCCTGTTATCCAGAACTTTTCATATGAGACCTTCCAGCAGAAGATGCTGCGC TTCCTGGAGAGCCACCTGGAA
Restriction Sites	Please inquire
ACCN	BC024890
Insert Size	1127 bp
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC024890.1, AAH24890.1
RefSeq Size	1127 bp
Locus ID	7014
Protein Families	Transcription Factors
Gene Summary	This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]

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