ADAM22 (NM_021723) Human Untagged Clone
CAT#: SC124720
ADAM22 (untagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1
CNY 6,640.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ADAM 22; DEE61; EIEE61; MDC2 |
Vector | PCMV6-Neo |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | NotI-NotI |
ACCN | NM_021723 |
Insert Size | 5270 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_021723.2, NP_068369.1 |
RefSeq Size | 9334 bp |
RefSeq ORF | 2721 bp |
Locus ID | 53616 |
UniProt ID | Q9P0K1 |
Domains | Reprolysin, DISIN, Pep_M12B_propep, ACR |
Protein Families | Druggable Genome, Protease, Transmembrane |
Gene Summary | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010] Transcript Variant: This variant (1), also known as epsilon, encodes isoform 1, which is proteolytically processed to generate the mature protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219272 | ADAM22 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 6,632.00 |
|
RC219272L1 | Lenti-ORF clone of ADAM22 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 11,400.00 |
|
RC219272L2 | Lenti-ORF clone of ADAM22 (mGFP-tagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 9,032.00 |
|
RC219272L3 | Lenti-ORF clone of ADAM22 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 11,400.00 |
|
RC219272L4 | Lenti-ORF clone of ADAM22 (mGFP-tagged)-Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 11,400.00 |
|
RG219272 | ADAM22 (tGFP-tagged) - Human ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1 |
CNY 10,450.00 |