PTP alpha (PTPRA) (NM_080841) Human Untagged Clone
CAT#: SC124914
PTPRA (untagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3
CNY 5,816.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_080841 edited
GGGCGGCCGCGAATTCGGCACGAGGGGATGATGCAGTTCAAATAACTAAGGACACATGTT CAAAGAGCATAATTAACTTTTTAAAAGAAGCTAATAAGCATGGATTCCTGGTTCATTCTT GTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAACAATGCTACCACAGTTGCACCT TCTGTAGGAATTACAAGATTAATTAACTCATCAACGGCAGAACCAGTTAAAGAAGAGGCC AAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCTGTGGCACCAACATTCAGCCCA AATATAACTCTGGGACCCACCTATTTAACCACTGTCAATTCTTCAGACTCTGACAATGGG ACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACAATTTCACCAAATGGAACGTGG CTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACC GCAGCAACCACTCCAGAAACTTTCCCTCCTTCAGATGAGACACCAATTATTGCGGTGATG GTGGCCCTGTCCTCTCTGCTAGTGATCGTGTTTATTATCATAGTTTTGTACATGTTAAGG TTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCTTATCCAACGGCCGC ACTGAGGATGTGGAGCCCCAGAGTGTGCCACTTCTGGCCAGATCCCCAAGCACCAACAGG AAATACCCACCCCTGCCCGTGGACAAGCTGGAAGAGGAAATTAACCGGAGAATGGCAGAC GACAATAAGCTCTTCAGGGAGGAATTCAACGCTCTCCCTGCATGTCCTATCCAGGCCACC TGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAATCGATATGTAAACATCTTGCCT TATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATC AATGCTTCATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCA AAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTGGGAACAAAACACAGCCACCATC GTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGAC CAAGGCTGCTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTG GACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGGCGACATGACCAACAGAAAGCCA CAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACC CCGATCGGCATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGG GCCATCGTGGTCCACTGCAGTGCAAGTGTAGGGCGTACAGGTACCTTTGTCGTCATTGAT GCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGG ATCCGGGCACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAA GCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACTGGAAGTGACCTCTCTAGAAACC CACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAG TTTAAGAAGTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCA GCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCCATATGAATTCAACAGAGTGATC ATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGC TACCGGCAGAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGAC TTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTATCGTGATGCTAACAGAACTGGAG GAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGA GATATTACAGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTC CTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGATCCGGCAGTTCCACTTCCATGGC TGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTG CAGAAGCAGCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCA GGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCTGGAGCGTGTGAAAGCAGAGGGG ATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAG ACACTGGAACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCA GATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCGTGGACCAGGAGGATTGCCTTTA ATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTG TTTTAGAAATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATG TGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGGGGAATTAAATAGTGTGATGTTT GGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATAC ATCTTTCCCTAAAGAAGATAAACACAAAATCCATTTCAGGTAGCTCGGCACCAACTAAGA AAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTGGTTGTCCCCGTACCACCATGCA CTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCAT GGGGAGTAATAGGACCAGAGCGGTATCTCTGGCACCACACTAGGGACTATCAGGTAATAA AAGCTTTGACTCCCTAAAAAAAAAAAAAAAAAAC >OriGene 5' read for NM_080841 unedited
GGTGCATATTTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGGATGATG CAGTTCAAATAACTAAGGACACATGTTCAAAGAGCATAATTAACTTTTTAAAAGAAGCTA ATAAGCATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGT GCCAACAATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCA ACGGCAGAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCT CTTTCTGTGGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACT GTCAATTCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGC ATTACAATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACA GAACCCTGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCA GATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTGATCGTGTTT ATTATCATAGTTTTGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCC AATTCTTTCCGCTTATCCAACGGCCGCACTGAGGATGTGGAGCCCCAGAGTGTGCCACTT CTGGCCAGATCCCCAAGCACCAACAGGAAATACCCACCCCTGCCCGTGGACAAGCTGGAA AGAGAAATTACCNGAGAATGGCAGACGACAATAAGCTCTTCAGGGAGGAATTCACGCTCT NCCTGCATGTNCTATCCAGGCCACCTGTGAAGCTGCTTNCAAGGAGGAAAACANGNNAAA AATCGATATGTAAACATCTGCCTAT >OriGene 3' read for NM_080841 unedited
TATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAGGGAGTCAAA GCTTTTATTACCTGATAGTCCCTAGTGTGGTGCCAGAGATACCGCTCTGGTCCTATTACT CCCCATGATATCAGTGGTGGGGATGGGGGAGGGGACCAGGGAGAGAGGGGAGGGATATTT ACAGTGCATGGTGGTACGGGGACAACCACTTTCCTCGAGAGCTCTGAGAACTTTGTGCTT TTTTTCTTAGTTGGTGCCGAGCTACCTGAAATGGATTTTGTGTTTATCTTCTTTAGGGAA AGATGTATTAACCAAAGCACAATCCAGCCCAATTTCTCGGCTGAGGATTTCACGATATCA ATCCAAACATCACACTATTTAATTCCCCAATAAAACATTGGAAAAAGGACTATCAGTGCT AACACATTTACATATAAAATTTCCACCTAATAGGTAATAGAAGCCTATGTACCAATTTCT AAAACAGTTATAAGATATATACACAATTTGGGGTATATTAACAAAACAGAATATTACAAA ATATTAAAGGCAATCCTCCTGGTCCACGGACCCTTGTTGCCGCTTACTTGAAGTTGGCAT AATCTGAGAATGCATCAATATACTCCTGCACCACCTTGTAGCAGAACTCATACTGTTCCA GTGTCTGGACCATGTGTGGCCTCTGTAGCCGCAGGCTCTTGACAGTCTGGAAGACATCCA AAATCCCCTCTGCTTTCACACGCTCCAGGACGGTGCTCANGGCACAGAANGGTCCCGTCC TTTCTGCCCCCGCGCTGCANTGCACGGTGATGGGGGTGGGTCCCTGACTGCTGCTGCTGC TTCTGCACGGCGGCGATGATGCTGATCATGCCCTTTCCGTCACTGGGGATGCCCACTTCA GCCCANCCTGGGAATGGGACTGGCCGGTCTGCCGGCTCTTATCTTCCTGGGGTGGTGCAC ACGAAGTCTTGACCGGGAGCTTTTAT |
Restriction Sites | NotI-NotI |
ACCN | NM_080841 |
Insert Size | 3200 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_080841.1, NP_543031.1 |
RefSeq Size | 3148 bp |
RefSeq ORF | 2382 bp |
Locus ID | 5786 |
UniProt ID | P18433 |
Domains | Y_phosphatase |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) contains an additional exon within the 5' UTR, and lacks an internal coding exon, when compared to variant 1. The resulting isoform (2) lacks a 9 aa internal segment, as compared to isoform 1. |
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Product Manuals |
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SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204392 | PTPRA (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3 |
CNY 5,808.00 |
|
RC204392L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3, Myc-DDK-tagged |
CNY 7,700.00 |
|
RC204392L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3, mGFP tagged |
CNY 7,700.00 |
|
RG204392 | PTPRA (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3 |
CNY 7,408.00 |
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