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MARCKS (NM_002356) Human Untagged Clone
CAT＃: SC125313
MARCKS (untagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 80K-L; MACS; PKCSL; PRKCSL |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125313 sequence for NM_002356 edited (data generated by NextGen Sequencing)
ATGGGTGCCCAGTTCTCCAAGACCGCAGCGAAGGGAGAAGCCGCCGCGGAGAGGCCTGGG GAGGCGGCTGTGGCCTCGTCGCCTTCCAAAGCGAACGGACAGGAGAATGGCCACGTGAAG GTAAACGGCGACGCTTCGCCCGCGGCCGCCGAGTCGGGCGCCAAGGAGGAGCTGCAGGCC AACGGCAGCGCCCCGGCCGCCGACAAGGAGGAGCCCGCGGCCGCCGGGAGCGGGGCGGCG TCGCCCTCCGCGGCCGAGAAAGGTGAGCCGGCCGCCGCCGCTGCCCCCGAGGCCGGGGCC AGCCCGGTAGAGAAGGAGGCCCCCGCGGAAGGCGAGGCTGCCGAGCCCGGCTCGCCCACG GCCGCGGAGGGAGAGGCCGCGTCGGCCGCCTCCTCGACTTCTTCGCCCAAGGCCGAGGAC GGGGCCACGCCCTCGCCCAGCAACGAGACCCCGAAAAAAAAAAAGAAGCGCTTTTCCTTC AAGAAGTCTTTCAAGCTGAGCGGCTTCTCCTTCAAGAAGAACAAGAAGGAGGCTGGAGAA GGCGGTGAGGCTGAGGCGCCCGCTGCCGAAGGCGGCAAGGACGAGGCCGCCGGGGGCGCA GCTGCGGCCGCCGCCGAGGCGGGCGCGGCCTCCGGGGAGCAGGCAGCGGCGCCGGGCGAG GAGGCGGCAGCGGGCGAGGAGGGGGCGGCGGGTGGCGACCCGCAGGAGGCCAAGCCCCAG GAGGCCGCTGTCGCGCCAGAGAAGCCGCCCGCCAGCGACGAGACCAAGGCCGCCGAGGAG CCCAGCAAGGTGGAGGAGAAAAAGGCCGAGGAGGCCGGGGCCAGCGCCGCCGCCTGCGAG GCCCCCTCCGCCGCCGGGCCCGGCGCGCCCCCGGAGCAGGAGGCAGCCCCCGCGGAGGAG CCCGCGGCCGCCGCAGCCTCGTCAGCCTGCGCAGCCCCCTCACAGGAGGCCCAGCCCGAG TGCAGTCCAGAAGCCCCCCCAGCGGAGGCGGCAGAGTAA Clone variation with respect to NM_002356.5 >OriGene 5' read for NM_002356 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCATTTTCCTCTTGT CTACAGTGCGGCTACAAATCTGGGATTTTTTTATTACTTCTTTTTTTTTCGAACTACACT TGGGCTCCTTTTTTGTGCTCGACTTTTCCACCCTTTTTCCCTCCCTCCTGTGCTGCTGCT TTTTGATCTCTTCGACTAAAATTTTTTTATCCGGAGTGTATTTAATCGGTTCTGTTCTGT CCTCTCCACCACCCCCACCCCCCTCCCTCCGGTGTGTGTGCCGCTGCCGCTGTTGCCGCC GCCGCTGCTGCTGCTCGCCCCGTCGTTACACCAACCCGAGGCTCTTTGTTTCCCCTCTTG GATCTGTTGAGTTTCTTTGTTGAAGAAGCCAGCATGGGTGCCCAGTTCTCCAAGACCGCA GCGAAGGGAGAAGCCGCCGCGGAGAGGCCTGGGGAGGCGGCTGTGGCCTCGTCGCCTTCC AAAGCGAACGGACAGGAGAATGGCCACGTGAAGGTAAACGGCGACGCTTCGCCCGCGGCC GCCGAGTCGGGCGCCAAGGAGGAGCTGCAGGCCAACGGCAGCGCCCCGGCCGCCGACAAG GAGGAGCCCGCGGCCGCCGGGAGCGGGGCGGCGTCGCCCTCCGCGGCCGAGAAAGGTGAG CCGGCCGCCGCCGCTGCCCCCGAGGCCGTGGCCAGCCCGGTAGAGAAAGAGGCCCCCGCG GAGGCGAAGCTGCCGACCCCGCTCGCCCACGTCGCGGAGGGAGAGGCCGCGTCCGCCGCC TTCTCGACTTCTTCGCCCAGGGCCGAGGACGGGCCCCGCCCTCGCCCAGCACGAGACCCG GAAAAAAAAAAGAAGCGCTTTTCCTTCAGGAAGTCTTTCAAGCTGAGCGGGCTTTTCCTT CAGAAGACCANAAAGGAGCTTGGAAAGGCGGGGAGGTTTTAGCC >OriGene 3' read for NM_002356 unedited
CTCTGCACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACATTTTATT CACATTTATTTTTCGCTTTTAGTGTGCTCACAGAAAATTAGAACACCTTAAGCAGGAGTT TAATAGCAATTTTTGTAAGCAAAGTTACATTCCATCTCTAAGTCAAATTGGTCAAAGCTT CTCCAGTATTTACAAAACATGATAGACAAGATGCTACACAAAACCATTGCATCTGAAGAT TTTTTTTCCTTTATTCTCAAAGACGACTGGAAAAGAAAGCATTATCTGCTGTAATCAAAA ACATACCACAGTATAAACAGTAACCATTCCACTTATCACAGCTTGGTTGAGTTTAAAATT TGTGTTTTAAAAGGTCCAAGATGACTGCAGTTTTACAAAAATGGGCAGGGTGGAAAGTTG CAAACTTCATGTGCTTCTGGATATCAAGATTTGTTTTTATACAATAGCCACAGTTAAAAA CACCCTGCTGGTAATACATAATTACACTTTATTAAGGTCATAAACCAGCAATAAACAATA AAGCCTATACAACTTGTAGTTCTACTTAATCACTGACTGGTACAGCTAACATGAGATAAG TGAAAAGTTCCTATGGTTTAAATGAACTGCTAAGACTATGATCGTCTCTTTTTTTTTAAA TCTGGCCCTTGGAGTCTTTTCTTTTTTCCCCTTTCCTTCTTACCTAAGACTTGTAGGGCC GGAAACCTGCCTCACAAAAACACGGTCATAACTTTACTTTAAAAAAAAAAAAAAAGACAC GCTTTACACATTTTCAGGGGCCCCTATTTGGCAATGGTAGGCCCCCTCTATTTGCTCTTG GGACCCCTATCACCCATTTGAATTCCCTTCTTGACCCCACTCTCCTCATATATGCCAGGC CTATATGACAAAAAGTTTCCCTTTTGATCAAGAGCAAGTTGCCCAACCTTATCCGTGCCC AAAATAAAACAAACAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002356 |
| Insert Size | 2560 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002356.4, NP_002347.4 |
| RefSeq Size | 2589 bp |
| RefSeq ORF | 999 bp |
| Locus ID | 4082 |
| UniProt ID | P29966 |
| Domains | MARCKS |
| Protein Families | Druggable Genome |
| Protein Pathways | Fc gamma R-mediated phagocytosis |
| Gene Summary | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Intracellular cavity of sensor domain controls allosteric gating of TRPA1 channel
,Zimova, L;Sinica, V;Kadkova, A;Vyklicka, L;Zima, V;Barvik, I;Vlachova, V;,
Sci Signal
,PubMed ID 29363587
[MARCKS]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210277 | MARCKS (Myc-DDK-tagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 3,600.00 |
|
| RC210277L1 | Lenti-ORF clone of MARCKS (Myc-DDK-tagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 6,000.00 |
|
| RC210277L2 | Lenti-ORF clone of MARCKS (mGFP-tagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 5,890.00 |
|
| RC210277L3 | Lenti-ORF clone of MARCKS (Myc-DDK-tagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 5,890.00 |
|
| RC210277L4 | Lenti-ORF clone of MARCKS (mGFP-tagged)-Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 5,890.00 |
|
| RG210277 | MARCKS (tGFP-tagged) - Human myristoylated alanine-rich protein kinase C substrate (MARCKS) |
CNY 5,200.00 |
