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TIP120A (CAND1) (NM_018448) Human Untagged Clone
CAT＃: SC125317
CAND1 (untagged)-Human cullin-associated and neddylation-dissociated 1 (CAND1)
CNY 8,568.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TIP120; TIP120A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | Please inquire |
| ACCN | NM_018448 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018448.2, NP_060918.2 |
| RefSeq Size | 5387 bp |
| RefSeq ORF | 3693 bp |
| Locus ID | 55832 |
| UniProt ID | Q86VP6 |
| Domains | TIP120 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Impact of Cand1 in Prostate Cancer
,Eigentler, A;Tymoszuk, P;Zwick, J;Schmitz, AA;Pircher, A;Kocher, F;Schlicker, A;Lesche, R;Schäfer, G;Theurl, I;Klocker, H;Heidegger, I;,
Cancers (Basel) 2020
,PubMed ID 32059441
[CAND1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208212 | CAND1 (Myc-DDK-tagged)-Human cullin-associated and neddylation-dissociated 1 (CAND1) |
CNY 8,568.00 |
|
| RC208212L1 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), Myc-DDK-tagged |
CNY 14,160.00 |
|
| RC208212L2 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), mGFP tagged |
CNY 14,160.00 |
|
| RC208212L3 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), Myc-DDK-tagged |
CNY 14,160.00 |
|
| RC208212L4 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), mGFP tagged |
CNY 10,968.00 |
|
| RG208212 | CAND1 (tGFP-tagged) - Human cullin-associated and neddylation-dissociated 1 (CAND1) |
CNY 13,490.00 |
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