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GATA2 (NM_032638) Human Untagged Clone
CAT＃: SC125368
GATA2 (untagged)-Human GATA binding protein 2 (GATA2), transcript variant 2
CNY 5,488.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DCML; IMD21; MONOMAC; NFE1B |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125368 sequence for NM_032638 edited (data generated by NextGen Sequencing)
ATGGAGGTGGCGCCGGAGCAGCCGCGCTGGATGGCGCACCCGGCCGTGCTGAATGCGCAG CACCCCGACTCACACCACCCGGGCCTGGCGCACAACTACATGGAACCCGCGCAGCTGCTG CCTCCAGACGAGGTGGACGTCTTCTTCAATCACCTCGACTCGCAGGGCAACCCCTACTAT GCCAACCCCGCTCACGCGCGGGCGCGCGTCTCCTACAGCCCCGCGCACGCCCGCCTGACC GGAGGCCAGATGTGCCGCCCACACTTGTTGCACAGCCCGGGTTTGCCCTGGCTGGACGGG GGCAAAGCAGCCCTCTCTGCCGCTGCGGCCCACCACCACAACCCCTGGACCGTGAGCCCC TTCTCCAAGACGCCACTGCACCCCTCAGCTGCTGGAGGCCCTGGAGGCCCACTCTCTGTG TACCCAGGGGCTGGGGGTGGGAGCGGGGGAGGCAGCGGGAGCTCAGTGGCCTCCCTCACC CCTACAGCAACCCACTCTGGCTCCCACCTTTTCGGCTTCCCACCCACGCCACCCAAAGAA GTGTCTCCTGACCCTAGCACCACGGGGGCTGCGTCTCCAGCCTCATCTTCCGCGGGGGGT AGTGCAGCCCGAGGAGAGGACAAGGACGGCGTCAAGTACCAGGTGTCACTGACGGAGAGC ATGAAGATGGAAAGTGGCAGTCCCCTGCGCCCAGGCCTAGCTACTATGGGCACCCAGCCT GCTACACACCACCCCATCCCCACCTACCCCTCCTATGTGCCGGCGGCTGCCCACGACTAC AGCAGCGGACTCTTCCACCCCGGAGGCTTCCTGGGGGGACCGGCCTCCAGCTTCACCCCT AAGCAGCGCAGCAAGGCTCGTTCCTGTTCAGAAGGCCGGGAGTGTGTCAACTGTGGGGCC ACAGCCACCCCTCTCTGGCGGCGGGACGGCACCGGCCACTACCTGTGCAATGCCTGTGGC CTCTACCACAAGATGAATGGGCAGAACCGACCACTCATCAAGCCCAAGCGAAGACTGTCG GCCGCCAGAAGAGCCGGCACCTGTTGTGCAAATTGTCAGACGACAACCACCACCTTATGG CGCCGAAACGCCAACGGGGACCCTGTCTGCAACGCCTGTGGCCTCTACTACAAGCTGCAC AATGTTAACAGGCCACTGACCATGAAGAAGGAAGGGATCCAGACTCGGAACCGGAAGATG TCCAACAAGTCCAAGAAGAGCAAGAAAGGGGCGGAGTGCTTCGAGGAGCTGTCAAAGTGC ATGCAGGAGAAGTCATCCCCCTTCAGTGCAGCTGCCCTGGCTGGACACATGGCACCTGTG GGCCACCTCCCGCCCTTCAGCCACTCCGGACACATCCTGCCCACTCCGACGCCCATCCAC CCCTCCTCCAGCCTCTCCTTCGGCCACCCCCACCCGTCCAGCATGGTGACCGCCATGGGC TAG Clone variation with respect to NM_032638.4 15 c=>g;490 g=>a >OriGene 5' read for NM_032638 unedited
CCCCCCTATATCCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCT ATATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAG CGGCCGCGAATTCGGCACGAGGGGCAGCTGGCGCCAGGGCGGCCGGAGGATGCCGAGGGG CCGGAGCCGGGCGGGCCCGAGGCCGAGGCGCACTCTACCCCCAGCTCCTACCCTGTAAGC CCCGCCAGCCTCCGGACGTGCTGTCCCTGGGCCCGTCGCCCTCGGGGCTCCCGCCGGAAC TCCTTCACTCTCAGAGGCCGAGTCCCTCCCCTCCCCACGGCTGCGTGTGGCCGTTGCCGT CTGCACCCAGACCCTGAGCCGCCGCCGCCGGCCATGGAGGTGGCGCCGGAGCAGCCGCGC TGGATGGCGCACCCGGCCGTGCTGAATGCGCAGCACCCCGACTCACACCACCCGGGCCTG GCGCACAACTACATGGAACCCGCGCAGCTGCTGCCTCCAGACGAGGTGGACGTCTTCTTC AATCACCTCGACTCGCAGGGCAACCCCTACTATGCCAACCCCGCTCACGCGCGGGCGCGC GTCTCCTACAGCCCCGCGCACGCCCGCCTGACCGGAGGCCAGATGTGCCGCCCACACTTG TTGCACAGCCCGGGTTTGCCCTGGCTGAACGGNGGCAAAGCAGCCCTCTCTGCCGCTGCG GCCCACCACCACAACCCCTGGACCGTGAGCCCCTTCTCCAAGACGCCACTGCACCCCTCA GCTGCTGGAGGCCCTGGAGGCCCACTCTCTGTGTACTCAGGGCTGGGGGGTGGGAGCGGN GGAGGCACCGGGAGCTCAGTGGCCTCCCTCACCTTAC >OriGene 3' read for NM_032638 unedited
CATGGAATGGCACTTCCAGGGCCAGNAAAGCACTGGGGNAGGGTCACAGGATGCCACCCG GGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTT TTTTTTTTTTTCACAAAAAGTATTTTATTATTCTTAACAGTACTCACTTTAAAGGAATAA GAGGATAGCATACATTTTTTACAGACAATATATAAATGTTGTACATAATTAACAATAACT TAGTTCACTAATCCAAAATAAAACAAGCCAAATAAAACATAAAAACAGAAAATACTGCCG ATTCTTTTTCTTATGCGGACACTAGTACAAAATAAGTTACTTCTGGCCGTGGTGCTCCCT GCAGCGACTGCCCGCCCATATTGCACTTGGTCACTACATCAGCACAATCCTCCTCCTGGG CCAGGGGCCCCTCACAGGCCACCACACCCCGCCGTCACCGCATACAGAATCTAAGCTCGG GACACGTTTATATACAGCTGTACCTTGGGAAGGATCCAGACAGCCACAGTAAAGCTGGAC CTGAGACCCCAGCAGGGACACAGCCTCTCCCTGGGTCCTGGTCCTGACCTGCCCCCAACT CCTGCCTTCACCCCCTGGCAGGCCAGCAAATGCCAACCAGCCCCCAGAAACCAGGGCAGC AAAGGCCCCTCCCCACCCCCAGCTTTCATACTAGGGCTGTGGGATCCCAGCTCTTTTCCA AAAAGATTTGCAAGCTCNCACCTGTGTGTAGGTTTTATTCCTTTCATAGCAGGGCTCCCT GTGCTACGTACATCAACTGGACCCAAAAGAGTTAAAAATAAACATTTACTCATCNCGAGT AAGCCCTAGCATTTTTTTAAAATTTTCTTTTGCCCAAAATAGAGCCAAGGGTTGAAGGTT AACAAAAAAGATGTTTTCAGGGTCCACCGAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032638 |
| Insert Size | 1443 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032638.3, NP_116027.2 |
| RefSeq Size | 3383 bp |
| RefSeq ORF | 1443 bp |
| Locus ID | 2624 |
| UniProt ID | P23769 |
| Domains | GATA |
| Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
| Gene Summary | This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
GATA2 Germline Mutations Impair GATA2 Transcription, Causing Haploinsufficiency: Functional Analysis of the p.Arg396Gln Mutation
,Cortés-Lavaud, X;Landecho, MF;Maicas, M;Urquiza, L;Merino, J;Moreno-Miralles, I;Odero, MD;,
J. Immunol.
,PubMed ID 25624456
[GATA2]
|
|
Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells
,Ikeda, R;Pak, K;Chavez, E;Ryan, AF;,
Mol. Neurobiol. July 2014
,PubMed ID 25015561
[GATA2]
|
|
Heritable GATA2 Mutations Associated with Familial Myelodysplastic Syndrome and Acute Myeloid Leukemia
,null,
Nature genetics
,PubMed ID 21892162
[GATA2]
|
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| RC208554L2 | Lenti ORF clone of Human GATA binding protein 2 (GATA2), transcript variant 2, mGFP tagged |
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| RC208554L4 | Lenti ORF clone of Human GATA binding protein 2 (GATA2), transcript variant 2, mGFP tagged |
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| RG208554 | GATA2 (tGFP-tagged) - Human GATA binding protein 2 (GATA2), transcript variant 2 |
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| SC321007 | GATA2 (untagged)-Human GATA binding protein 2 (GATA2), transcript variant 2 |
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