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Calcium independent Phospholipase A2 (PLA2G6) (NM_001004426) Human Untagged Clone
CAT＃: SC125777
PLA2G6 (untagged)-Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2
CNY 5,512.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PNPLA9 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001004426 edited
GGAAGTAGAAGTGCTGAGTAAGCCGAGACAGAGGGGGAAGACGGTGGGGCCTCCCCACCT GCCCCGCAGAAGATGCAGTTCTTTGGCCGCCTGGTCAATACCTTCAGTGGCGTCACCAAC TTGTTCTCTAACCCATTCCGGGTGAAGGAGGTGGCTGTAGCCGACTACACCTCGAGTGAC CGAGTTCGGGAGGAAGGGCAGCTGATTCTGTTCCAGAACACTCCCAACCGCACCTGGGAC TGCGTCCTGGTCAACCCCAGGAACTCACAGAGTGGATTCCGACTCTTCCAGCTGGAGTTG GAGGCTGACGCCCTAGTGAATTTCCATCAGTATTCTTCCCAGCTGCTACCCTTCTATGAG AGCTCCCCTCAGGTCCTGCACACTGAGGTCCTGCAGCACCTGACCGACCTCATCCGTAAC CACCCCAGCTGGTCAGTGGCCCACCTGGCTGTGGAGCTAGGGATCCGCGAGTGCTTCCAT CACAGCCGTATCATCAGCTGTGCCAATTGCGCGGAGAACGAGGAGGGCTGCACACCCCTG CACCTGGCCTGCCGCAAGGGTGATGGGGAGATCCTGGTGGAGCTGGTGCAGTACTGCCAC ACTCAGATGGATGTCACCGACTACAAGGGAGAGACCGTCTTCCATTATGCTGTCCAGGGT GACAATTCTCAGGTGCTGCAGCTCCTTGGAAGGAACGCAGTGGCTGGCCTGAACCAGGTG AATAACCAAGGGCTGACCCCGCTGCACCTGGCCTGCCAGCTGGGGAAGCAGGAGATGGTC CGCGTGCTGCTGCTGTGCAATGCTCGGTGCAACATCATGGGCCCCAACGGCTACCCCATC CACTCGGCCATGAAGTTCTCTCAGAAGGGGTGTGCGGAGATGATCATCAGCATGGACAGC AGCCAGATCCACAGCAAAGACCCCCGTTACGGAGCCAGCCCCCTCCACTGGGCCAAGAAC GCAGAGATGGCCCGCATGCTGCTGAAACGGGGCTGCAACGTGAACAGCACCAGCTCCGCG GGGAACACGGCCCTGCACGTGGCGGTGATGCGCAACCGCTTCGACTGTGCCATAGTGCTG CTGACCCACGGGGCCAACGCGGATGCCCGCGGAGAGCACGGCAACACCCCGCTGCACCTG GCCATGTCGAAAGACAACGTGGAGATGATCAAGGCCCTCATCGTGTTCGGAGCAGAAGTG GACACCCCGAATGACTTTGGGGAGACTCCTACATTCCTAGCCTCCAAAATCGGCAGACAA CTACAGGATCTCATGCACATCTCACGGGCCCGGAAGCCAGCGTTCATCCTGGGCTCCATG AGGGACGAGAAGCGGACCCACGACCACCTGCTGTGCCTGGATGGAGGAGGAGTGAAAGGC CTCATCATCATCCAGCTCCTCATCGCCATCGAGAAGGCCTCGGGTGTGGCCACCAAGGAC CTGTTTGACTGGGTGGCGGGCACCAGCACTGGAGGCATCCTGGCCCTGGCCATTCTGCAC AGTAAGTCCATGGCCTACATGCGCGGCATGTACTTTCGCATGAAGGATGAGGTGTTCCGG GGCTCCAGGCCCTACGAGTCGGGGCCCCTGGAGGAGTTCCTGAAGCGGGAGTTTGGGGAG CACACCAAGATGACGGACGTCAGGAAACCCAAGGTGATGCTGACAGGGACACTGTCTGAC CGGCAGCCGGCTGAACTCCACCTCTTCCGGAACTACGATGCTCCAGAAACTGTCCGGGAG CCTCGTTTCAACCAGAACGTTAACCTCAGGCCTCCAGCTCAGCCCTCAGACCAGCTGGTG TGGCGGGCGGCCCGAAGCAGCGGGGCAGCTCCTACTTACTTCCGACCCAATGGGCGCTTC CTGGACGGTGGGCTGCTGGCCAACAACCCCACGCTGGATGCCATGACCGAGATCCATGAG TACAATCAGGACCTGATCCGCAAGGGTCAGGCCAACAAGGTGAAGAAACTCTCCATCGTT GTCTCCCTGGGGACAGGGAGGTCCCCACAAGTGCCTGTGACCTGTGTGGATGTCTTCCGT CCCAGCAACCCCTGGGAGCTGGCCAAGACTGTTTTTGGGGCCAAGGAACTGGGCAAGATG GTGGTGGACTGTTGCACGGATCCAGACGGGCGGGCTGTGGACCGGGCACGGGCCTGGTGC GAGATGGTCGGCATCCAGTACTTCAGATTGAACCCCCAGCTGGGGACGGACATCATGCTG GATGAGGTCAGTGACACAGTGCTGGTCAACGCCCTCTGGGAGACCGAGGTCTACATCTAT GAGCACCGCGAGGAGTTCCAGAAGCTCATCCAGCTGCTGCTCTCACCCTGAGGGTCCCCA GCCTCTCACCGGCCCCAGCTGACCTCGTCCATTCAGCCCCTGCCAGGCCAAGCCCAGCCA CTGCCCTCCCGGGCAGATCTGGGCCCAGGCACCTCTGAGTCCATAGACCAGGCCTGGGAG AATGCCAAGCTGCCTGCCCGAGGCTGGTCCTGAAGGCCTGTCTCCCACTAACCCCGCCTT CCAGCACTTTCTGTCATTCCAGGCTGGGAAAGTCTAGAGCCCCCTTTGGCCCCTTTCCCT GACTGTCAAGGACAACTGACTCCCCCATCAGCTCAAACATTAAGGGTACCCGGGCACAAC CGTACCCCTGCCCCCAGCCCCAGCCTCCCTGAGGGCCTGCCGGGCTGCCTCTGCCCCAGC CCCCAGCAAGGGCACTCCCAGGCTTCCTGGTGGGTGCAGCCCACTCCCTCTGCCCTCTGC TCCGTTCCCTGGGGGCTGGGACTAAAGAAATGGGTGTCCCCCACCCCATCAGCTGGGAAA GCCCAGGCCGCAGGAGTGGGATGCCCGTTGGACTTTGCCCCTCACACTGGCCCAGCCCCT CACACTGCCCCACCCCGAGAACCCTCAGCTCTCAAAGGTCACTCCTGGGAGTTTCTTCTT CCCAATGGAAGTGGCTTAAGAGCCAAAACTGAAATAAATCATTTGGATTCAAAAAAAAAA AAAAAAAAAAAAAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001004426 unedited
NGGGGGTTTAGAATTTGTAATACGACTTACTATAGNNGGCGGCCGCGNAATTCCCGGGAT GGAAGTAGAAGTGCTGAGTAAGCCGAGACAGAGGGGAAGACGGTGGGGCCTCCCCACCTG CCCCGCAGAAGATGCAGTTCTTTGGCCGCCTGGTCAATACCTTCAGTGGCGTCACCAACT TGTTCTCTAACCCATTCCGGGTGAAGGAGGTGGCTGTAGCCGACTACACCTCGAGTGACC GAGTTCGGGAGGAAGGGCAGCTGATTCTGTTCCAGAACACTCCCAACCGCACCTGGGACT GCGTCCTGGTCAACCCCAGGAACTCACAGAGTGGATTCCGACTCTTCCAGCTGGAGTTGG AGGCTGACGCCCTAGTGAATTTCCATCAGTATTCTTCCCAGCTGCTACCCTTCTATGAGA GCTCCCCTCAGGTCCTGCACACTGAGGTCCTGCAGCACCTGACCGACCTCATCCGTAACC ACCCCAGCTGGTCAGTGGCCCACCTGGCTGTGGAGCTAGGGATCCGCGAGTGCTTCCATC ACAGCCGTATCATCAGCTGTGCCAATTGCGCGGAGAACGAGGAGGGCTGCACACCCCTGC ACCTGGCCTGCCGCAAGGGTGATGGGGAGATCCTGGTGGAGCTGGTGCAGTACTGCCACA CTCAGATGGATGTCACCGACTACAAGGGAGAGACCGTCTTCCATTATGCTGTCCAGGGTG ACAATTCTCANGTGCTGCAGCNTCTTGGAAGGAACGCAGTGGCTGGCCTGAACCANGTGA ATAACCAAGGGCTGACCCCGCTGCACCTGGCCTGCCAGCTGGGGAAGCAAGAGAATGTCC GCGTGCTGCTGCTGTGCCATGCTTCGTGCAACATCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001004426 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001004426.1, NP_001004426.1 |
| RefSeq Size | 3077 bp |
| RefSeq ORF | 2259 bp |
| Locus ID | 8398 |
| UniProt ID | O60733 |
| Protein Pathways | alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway |
| Gene Summary | The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010] Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2, 3, 5 and 6 encode the same isoform (b). Isoform b is found in the cytoplasm while isoform a is membrane-bound. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208735 | PLA2G6 (Myc-DDK-tagged)-Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2 |
CNY 5,512.00 |
|
| RC208735L1 | Lenti ORF clone of Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, Myc-DDK-tagged |
CNY 7,912.00 |
|
| RC208735L2 | Lenti ORF clone of Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC208735L3 | Lenti ORF clone of Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208735L4 | Lenti ORF clone of Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG208735 | PLA2G6 (tGFP-tagged) - Human phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2 |
CNY 7,112.00 |
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