COX7C (BC001005) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	cytochrome-c oxidase chain VIIc; cytochrome c oxidase subunit VIIc
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC001005 edited CAAGGTCGTGAAAAAAAAGGTCTTGGTGAGGTGCCGCCATTTCATCTGTCCTCATTCTCT GCGCCTTTCGCAGAGCTTCCAGCAGCGGTATGTTGGGCCAGAGCATCCGGAGGTTCACAA CCTCTGTGGTCCGTAGGAGCCACTATGAGGAGGGCCCTGGGAAGAATTTGCCATTTTCAG TGGAAAACAAGTGGTCGTTACTAGCTAAGATGTGTTTGTACTTTGGATCTGCATTTGCTA CACCCTTCCTTGTAGTAAGACACCAACTGCTTAAAACATAAGGATGTTTCAGTTCCTCCA TTTAACAGATATGAAGAGCATTTTAAGAGGTGCAGCCTCTGGAAGTGGATCAAACTAGAA CTCATATGCCATACTAGATATGTTTGTCAATAAACTTATGACGTGAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC001005 unedited TACATTTTGTAATACGCACTCTACTATAGGGCGGGCCGCGCAATTCCGCACGAGGCAAGG TCGTGAAAAAAAAGTCTTGGTGAGGGGCCGCCATTTCATCTGTCCTCATTCTCTGCGCCT TTCGCAGAGCTTCCAGCAGCGGTATGTTGGGCCAGAGCATCCGGAGGTTCACAACCTCTG TGGTCCGTAGGAGCCACTATGAGGAGGGCCCTGGGAAGAATTTGCCATTTTCAGTGGAAA ACAAGTGGTGGTTACTAGCTAAGATGTGTTTGTACTTTGGATCTGCATTTGCTACACCCT TCCTTGTAGTAAGACACCAACTGCTTAAAACATAAGGATGTTTCAGTTCCTCCATTTAAC AGATATGAAGAGCATTTTAAGAGGTGCAGCCTCTGGAAGTGGATCAAACTAGAACTCATA TGCCATACTAGATATGTTTGTCAATAAACTTATGACGTGNGAAAAAAAAANAAAAANAAA AAAAAAAAAAAAAAAAAAAANCCTCGGCTCTAGATTGCGGCCGCGGTCATAGCTGTTTCC TGAACAGATCCGGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGGCCTGGGA GGTGCCACTCCAGTGCGCACCAGCCTTGTCCCTATAAAATTAGGTTGCATCATTTTGTCT GACTAGGTGTCCTTCTATAATATTATGGGGTGGAGGGGGGGGGGTTTTGGACACAAGGGG CAAATTTGGGAAAAACAACCTGAGGGGGCCTGGGGGGTCTAATGGGGAACCAAGGCTGNA GTGCACAGGGCCCAATCTGGGGTCATTGAAATCTCCCGCTCCTGGGGTTAAAGGATTCTT CCTGGCTAAACCTCCCAAGTGGTGGGGGTTCCCGGCTGGGGTGACCCGGGCTCAATTAAT TTTTGTGTTTTTGGGAAGAACGGGGTGCCCCCATTTGGGGCGGGCGGGTCTCCAACCCTA AATCAGGGGGATCCCCCCCCTTGGGCCCCCA
Restriction Sites	Please inquire
ACCN	BC001005
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC001005.2, AAH01005.1
RefSeq Size	448 bp
Locus ID	1350
Protein Pathways	Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Gene Summary	Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]

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